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HP1421

Victor ID 376
Gene Name HP1421
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899874
NCBI Protein GI 15646030
Locus Tag HP1421
Protein Accession NP_208212.1
Other Database IDs UniProtKB-ID: O25965_HELPY
UniRef100: UniRef100_O25965
UniRef90: UniRef90_B2UVG1
UniRef50: UniRef50_B6JNK8
UniParc: UPI00000D30CE
EMBL: AE000511
EMBL-CDS: AAD08463.1
RefSeq_NT: NC_000915.1
DIP: DIP-3731N
MINT: MINT-169065
GenomeReviews: AE000511_GR
KEGG: hpy:HP1421
NMPDR: fig|85962.1.peg.1408
TIGR: HP_1421
HOGENOM: HBG500405
OMA: GHNILIS
ProtClustDB: CLSK694835
Taxonomy ID 85962
Gene Starting Position 1490989
Gene Ending Position 1491903
Gene Strand (Orientation) -
Protein Name conjugative transfer regulon protein (trbB)
DNA Sequence 
>gi|15644634:1490989-1491903 Helicobacter pylori 26695, complete genome
TTTAAAGCTCTTTAGTCCATAAGACTTCAGCGATTTGGCGCTCATTGTTGATTCTATTCACATGCACGAT
CACATCAATCGCGCTCTTAAAATACGCTCGCATCAAATCCTTATCCAAAGAATACATGTAACGCATGCTT
AAATTCAGTGAAAGGGCTTCTAAAGTGTTTTGAGCGCTATTAGCGTGAATAGTTGAGAGCATGCCCTTAT
GCCCGGTGTTTCCTAAACGCAAAAAGAGCGCTGCATTCCTAGTATCAATCTCGCCCACAATGAGCCTGTC
TGGGTTTAAGCGCATGGCCATATTGAGAGCGTCTTCATAATTAAAGCGCGTGTTTTCTTGCTTGCCCACT
AAAAGCCCCACGCAATTACTAAACGCTTTTAAATCCAATTCTTGGCTGTCTTCAACGCTCACCACCCTTT
CGTCTTTATTGACGCAATCTAAAAGAGCGTTTAATAGGCTTGTTTTACCGCTTGAAGTCTCCCCGCTAAT
GAGAATGTTATGCCCTTTAAGCGCTAAATCTTTCAAACTTTTTGGATCGCTTGCTTTGAAAGTGAAATCC
TCTAAACTTAAGGGCTTAAGCCTAGGCACACGGATATTGAGCGTGATTTGATTGTTCGTGGTGATGCTAA
AATGATTCGCGCTCACCCTATAGCGCGTGAAAGGGATAGAACAATTTAAGGTGGGGTGCTCTTCATCAAA
AAACAATCCCCTAAAACTAGCCAATTGCTCGCAAAACCTCAGCAAAAACGCCTTATCAAAAAGTGCATGC
CCTCTTTTTTCTCGGGTGTTATTGACTTTATAAAGCCAAAGCTCCTGCTCGGTATTGATCATCAGCTCTG
TGATCCCGCTTTCTAAAAAAGGGGTAAAATGGCCAATTAGGGCTTGTAAAACTCTATGGGTTTGTAAAGT
TTTCA
Protein Sequence 
>gi|15646030|ref|NP_208212.1| conjugative transfer regulon protein TrbB [Helicobacter pylori 26695] MKTLQTHRVLQALIGHFTPFLESGITELMINTEQELWLYKVNNTREKRGHALFDKAFLLRFCEQLASFRGLFFDEEHPTLNCSIPFTRYRVSANHFSITTNNQITLNIRVPRLKPLSLEDFTFKASDPKSLKDLALKGHNILISGETSSGKTSLLNALLDCVNKDERVVSVEDSQELDLKAFSNCVGLLVGKQENTRFNYEDALNMAMRLNPDRLIVGEIDTRNAALFLRLGNTGHKGMLSTIHANSAQNTLEALSLNLSMRYMYSLDKDLMRAYFKSAIDVIVHVNRINNERQIAEVLWTKEL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP1421 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG0630NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].