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espA from Escherichia coli O26:H11 str. 11368

Victor ID 3758
Gene Name espA from Escherichia coli O26:H11 str. 11368
Sequence Strain (Species/Organism) Escherichia coli O26:H11 str. 11368
NCBI Gene ID 8482581
NCBI Protein GI 260858274
Locus Tag ECO26_5283
Protein Accession YP_003232165.1
Other Database IDs UniProtKB-ID: C8TNU2_ECO26
UniRef100: UniRef100_O33976
UniRef90: UniRef90_O33976
UniRef50: UniRef50_O87743
UniParc: UPI0000031520
EMBL: AP010953
EMBL-CDS: BAI28425.1
RefSeq_NT: NC_013361.1
EnsemblGenome: EBESCG00000170182.
EnsemblGenome_TRS: EBESCT00000170778
EnsemblGenome_PRO: EBESCP00000164844
GenomeReviews: AP010953_GR
KEGG: eoj:ECO26_5283
ProtClustDB: CLSK701598
Taxonomy ID 573235
Gene Starting Position 5360174
Gene Ending Position 5360752
Gene Strand (Orientation) +
Protein Name translocator EspA
DNA Sequence 
>gi|260853213:5360174-5360752 Escherichia coli O26:H11 str. 11368, complete genome
CATGGATACATCAACTGCAACATCAGTTGCTAGTGCGAACGCGAGTACTTCGACATCGACAGTCTATGAC
TTAGGCAGTATGTCGAAAGACGAAGTAGTTCAGCTATTTAATAAAGTCGGTGTTTTTCAGGCTGCGCTTC
TCATGTTTGCCTATATGTATCAGGCACAAAGCGATCTGTCGATTGCAAAGTTTGCTGATATGAATGAGGC
ATCTAAGGAGTCAACCACAGCCCAAAAAATGGCTAATCTTGTGGATGCTAAAATTGCTGATGTTCAGAGT
AGTTCTGACAAGAATAAGAAAGCCAAACTTCCTCAAGAAGTGATTGACTATATAAATGATCCTCGCAATG
ACATTACAGTAAGTGGTATTAGCGATCTAAATGCTGAATTAGGCGCTGGTGATTTGCAAACGGTGAAGGC
CGCTATTTCGGCCAAATCGAATAACTTGACCACGGTAGTGAATAATAGCCAGCTTGAAATACAGCAAATG
TCAAATACGTTAAACCTATTAACGAGTGCACGTTCTGATATTCAGTCACTGCAATACAGAACTATTTCAG
CAATATCCCTTGGTAAATA
Protein Sequence 
>gi|260858274|ref|YP_003232165.1| translocator EspA [Escherichia coli O26:H11 str. 11368] MDTSTATSVASANASTSTSTVYDLGSMSKDEVVQLFNKVGVFQAALLMFAYMYQAQSDLSIAKFADMNEASKESTTAQKMANLVDAKIADVQSSSDKNKKAKLPQEVIDYINDPRNDITVSGISDLNAELGAGDLQTVKAAISAKSNNLTTVVNNSQLEIQQMSNTLNLLTSARSDIQSLQYRTISAISLGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of espA in STEC abolished ability to attach to HeLa cells and induce actin rearrangements (Ebel et al., 1998).
References
Ebel et al., 1998: Ebel F, Podzadel T, Rohde M, Kresse AU, Krämer S, Deibel C, Guzmán CA, Chakraborty T. Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages. Molecular microbiology. 1998; 30(1); 147-161. [PubMed: 9786192].