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espD from Escherichia coli O26:H11 str. 11368

Victor ID 3748
Gene Name espD from Escherichia coli O26:H11 str. 11368
Sequence Strain (Species/Organism) Escherichia coli O26:H11 str. 11368
NCBI Gene ID 8480969
NCBI Protein GI 260858275
Locus Tag ECO26_5284
Protein Accession YP_003232166.1
Other Database IDs UniProtKB-ID: C8TNU3_ECO26
UniRef100: UniRef100_O88127
UniRef90: UniRef90_O88127
UniRef50: UniRef50_P71215
UniParc: UPI0000031521
EMBL: AP010953
EMBL-CDS: BAI28426.1
RefSeq_NT: NC_013361.1
EnsemblGenome: EBESCG00000174834.
EnsemblGenome_TRS: EBESCT00000171953
EnsemblGenome_PRO: EBESCP00000163548
GenomeReviews: AP010953_GR
KEGG: eoj:ECO26_5284
ProtClustDB: CLSK334861
Taxonomy ID 573235
Gene Starting Position 5360765
Gene Ending Position 5361907
Gene Strand (Orientation) +
Protein Name translocator EspD
DNA Sequence 
>gi|260853213:5360765-5361907 Escherichia coli O26:H11 str. 11368, complete genome
TATGCTTAATGTAAATAGCGATATCCAGTCTATGAGGTCTGGGGCCAGCGCTGCTACGGCTACTTCAGGT
ATTAATCAGCCTGAAGTGACTTCCGCGCTGGATTTACAACTGGTTAAATCCACGGCCCCATCAGCAAGTT
GGACAGAAAGTACCGCTTTACCAACGCCACCGGCAGGACACTCATTAGTGACGCCCTCTGTTGCTGAGGA
TGTCCTGAGTAAACTGTTTGGTGGTATTAGTGGTGAAGTTAGGAGTCGAACAGAGGGAACCGAACCACAG
CGCAGCACTCAGAATGCAAGCTCTGGCTATCCTTATCTTTCTCAGGTGAATAACGTTGACCCTCAGGCCA
TGATGATGATGGTCACCCTGTTATCCCTGGATGCTTCAGCGCAGAAAGTTGCGAGTATGAAAAACTCCAA
CGAGATCTACACGGATGGGCAAAATAAGGCGCTGGATAATAAAACGCTGGAGTTTAAAAAGCAGCTCGAA
GAACAACAGAAAGCCGAAGAGAAAGCACAAAAAAGTAAAATTCTTGGTCAGGTCTTTGGTTGGTTGGGCG
TCGCGGTAACTGCTATTGCAGCTATTTTTAACCCGGCACTCTGGGCTGTTGTTGCCGTTAGCGCAACAGC
AATGGCACTGCAAACTGCAGTTGATGTAATGGGCGATAAGGCCCCGCAGGCGTTAAAGACAGCAGCGCAA
GTCTTTGGCGGAGTATCTATTGCTGCAAGTATTCTGACAGCCGGCATTGGCGGGGTGTCTTCACTTATGT
CTAAAGTTGGCGATGTCGCTAACAAAGTTGGTTCAAACATCGTGAAAACAGTTACTAAACTGGCCGATGT
ATTTGTTGAGAACGTTGTTTCAAAAGTTGCGGCAACGGCAAATGGATTTACGACCTCTGCACGTTCTATT
GGGACAACTGTGCTGAATAATGATTCTGCGCAATACAGCATATTGGCTCAGTTATCTGCTTACGCGGTAC
AAAACTTAACTCGACAGAGTGAAAACCTGGGTGAGAGTGCGAAGGTTGAGCTGGATAAAGCTGCAGCCGA
GTTGCGAAACCAGGCAAGCTATTTACAAAATGCTTCTCAGTTAATATCCGACTCAGCACGAGTAAATAGC
CGTATTGTTAGTGGTCGAGTTTA
Protein Sequence 
>gi|260858275|ref|YP_003232166.1| translocator EspD [Escherichia coli O26:H11 str. 11368] MLNVNSDIQSMRSGASAATATSGINQPEVTSALDLQLVKSTAPSASWTESTALPTPPAGHSLVTPSVAEDVLSKLFGGISGEVRSRTEGTEPQRSTQNASSGYPYLSQVNNVDPQAMMMMVTLLSLDASAQKVASMKNSNEIYTDGQNKALDNKTLEFKKQLEEQQKAEEKAQKSKILGQVFGWLGVAVTAIAAIFNPALWAVVAVSATAMALQTAVDVMGDKAPQALKTAAQVFGGVSIAASILTAGIGGVSSLMSKVGDVANKVGSNIVKTVTKLADVFVENVVSKVAATANGFTTSARSIGTTVLNNDSAQYSILAQLSAYAVQNLTRQSENLGESAKVELDKAAAELRNQASYLQNASQLISDSARVNSRIVSGRV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].