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escN from Escherichia coli O26:H11 str. 11368

Victor ID 3747
Gene Name escN from Escherichia coli O26:H11 str. 11368
Sequence Strain (Species/Organism) Escherichia coli O26:H11 str. 11368
NCBI Gene ID 8480968
NCBI Protein GI 260858262
Locus Tag ECO26_5271
Protein Accession YP_003232153.1
Other Database IDs UniProtKB-ID: C8TNT0_ECO26
UniRef100: UniRef100_C8TNT0
UniRef90: UniRef90_O85632
UniRef50: UniRef50_O85632
UniParc: UPI0001B5AFD1
EMBL: AP010953
EMBL-CDS: BAI28413.1
RefSeq_NT: NC_013361.1
EnsemblGenome: EBESCG00000175013.
EnsemblGenome_TRS: EBESCT00000174995
EnsemblGenome_PRO: EBESCP00000164724
GenomeReviews: AP010953_GR
KEGG: eoj:ECO26_5271
ProtClustDB: CLSK334788
Taxonomy ID 573235
Gene Starting Position 5346942
Gene Ending Position 5348282
Gene Strand (Orientation) +
Protein Name T3SS structure protein EscN
DNA Sequence 
>gi|260853213:5346942-5348282 Escherichia coli O26:H11 str. 11368, complete genome
AATGATTTTAGAGCATGATTCTGTATTGGAAAGATACCCACGTATCCAGAAAGTGCTCAATAGCACTGTG
CCGACATTATCATTAAATTCGTCTACCAGATATGAAGGCAAGATTACCAATATCGGCGGGACGATTATCA
AGGCGCGTTTACCAAAAGCGCGTATTGGTGCCTTTTACAAGATAGAACCCAGTCAACGTTTAGCTGAGGT
GATCGCTATTGATGAAGATGAGGTTTTCCTGCTGCCTTTTGAGCATATTTCCGGCATGTATTGTGGCCAG
TGGCTAAGTTATCAGGGGGAAGAGTTCAAGATTCGTGTTGGGGACGAACTCCTTGGGCGACTGGTTGATG
GTATAGGCAGACCAATGGGGAGCAATATTACTGCACCTTATCTTCCGTTTGAACGCAGTTTGTATGCTGA
ACCCCCCGATCCTTTATTAAGGCAGGTTATTGATCAGCCATTTACGCTTGGCGTCAGGGCAATAGATGGT
TTACTTACTTGCGGTATTGGGCAACGCATCGGTATTTTCGCGGGGTCCGGCGTTGGTAAAAGTACGCTTT
TGGGAATGATTTGTAATGGCGCATCCGCGGATATTATTGTCCTTGCCCTTATCGGCGAGCGTGGTCGCGA
AGTAAATGAATTCCTCGCGCTTTTACCTCAATCCACGCTTTCTAAATGTGTACTGGTCGTCACAACGTCA
GACCGTCCCGCGCTGGAAAGAATGAAGGCCGCATTTACGGCGACAACCATTGCAGAGTTCTTCCGGGATC
AGGGCAAAAATGTATTATTAATGATGGATTCCGTAACTCGTTATGCCCGAGCCGCGCGTGATGTTGGGCT
TGCATCGGGAGAGCCTGATGTAAGAGGGGGATTCCCTCCGAGTGTTTTTGCCTCGTTACCCAAATTATTA
GAGCGTGCGGGACCTGCGCCAAAAGGTTCAATAACTGCGATTTATACGGTGCTGTTAGAAAGCGATAATG
TGAATGATCCCATCGGTGATGAAGTTCGCTCTATTCTTGATGGACATATTGTGCTTACCCGAGAACTTGC
AGAGGAAAACCATTTCCCTGCAATTGATATTGGTTTAAGCGCCAGTCGTGTTATGCATAACGTTGTTAAA
TCGGAACATTTACGTGCAGCGGCTGAATGCAAAAAGCTTATTGCAACCTATAAGAATATTGAACTGCTTA
TTCGTATTGGTGAGTACACGATGGGGCAAGATCCTGAAGCGGATAAGGCAATAAAAAACAGGAAAGCAAT
TCAGAGCTTTATACAACAAAGCACCAAAGATATCAGTAGTTACGAAAAAACGATTGAAAGCCTATTCAAA
GTGGTTGCCTG
Protein Sequence 
>gi|260858262|ref|YP_003232153.1| T3SS structure protein EscN [Escherichia coli O26:H11 str. 11368] MILEHDSVLERYPRIQKVLNSTVPTLSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFLLPFEHISGMYCGQWLSYQGEEFKIRVGDELLGRLVDGIGRPMGSNITAPYLPFERSLYAEPPDPLLRQVIDQPFTLGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEFFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFASLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVKSEHLRAAAECKKLIATYKNIELLIRIGEYTMGQDPEADKAIKNRKAIQSFIQQSTKDISSYEKTIESLFKVVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of escN abolished pathogenicity in infant rabbits compared to wild-type EHEC (Ritchie and Waldor, 2005).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Ritchie and Waldor, 2005: Ritchie JM, Waldor MK. The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infection and immunity. 2005; 73(3); 1466-1474. [PubMed: 15731044].