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espD from Escherichia coli O111:H- str. 11128

Victor ID 3726
Gene Name espD from Escherichia coli O111:H- str. 11128
Sequence Strain (Species/Organism) Escherichia coli O111:H- str. 11128
NCBI Gene ID 8486431
NCBI Protein GI 260869673
Locus Tag ECO111_3739
Protein Accession YP_003236075.1
Other Database IDs UniProtKB-ID: C8UFK2_ECO1A
UniRef100: UniRef100_B8ZY87
UniRef90: UniRef90_B8ZY87
UniRef50: UniRef50_P71215
UniParc: UPI00019234D0
EMBL: AP010960
EMBL-CDS: BAI37524.1
RefSeq_NT: NC_013364.1
EnsemblGenome: EBESCG00000183866.
EnsemblGenome_TRS: EBESCT00000185674
EnsemblGenome_PRO: EBESCP00000171357
GenomeReviews: AP010960_GR
KEGG: eoi:ECO111_3739
ProtClustDB: CLSK334861
Taxonomy ID 585396
Gene Starting Position 3723531
Gene Ending Position 3724673
Gene Strand (Orientation) -
Protein Name translocon EspD
DNA Sequence 
>gi|260866153:3723531-3724673 Escherichia coli O111:H- str. 11128, complete genome
ATTAAACTCGACCGCTGACAATACGGCTATTCACTCGCGCAGAATCAGAAATTAGCTTAGAAGCACTCTG
TATATAATTCGCCTGGTTTTGCACCTCGAGTGCGGCTTTATCCAGCTCTGCCTTCGCACTCTGACTTAAG
CTTTCACTTTGTCGAGTTAAATTTTCCACAACAAAAGAAGAAATCTGTGATAACAGATTATGATTCGCTG
CGTCATTATTCAGCACAGTTGTACCAATAGAGCGCGAAGAAGTGGTTAAACCATTTGCCACAGCCGAAAT
TTTCGATGCAACGTTTTCGACAAGAGTGTCGGCCAACGTAGTGACCGCTTTTACGATGTTTGAACCCACT
TTGCCAGCCACATCGCCAACTTTAGACATAAGTGAAGACACCCCGCCAATGCCGGCTGTCAGAATACCTG
CGGCAAGAGATAGACCGCCAAAAGCTTGCGCTGCTGTTTTTAACGCCTGCGGAGCCTTATCGCCCATAAC
ATCAACCGCAGTTTGCAGCGCCATTGCTGTTGCACTAACAGCAACAACAGCCCAGAGAGCTGGGTTAAAA
ATAGCTGCAACAGCAGTTACCGCAACCCCTAACCAACCAAAGACCTGACCAACAATTTTACTTTTTTGTG
CTTTCTCTTCGGCTTTCTGTTGTTCTTCAAGCTGTTTTTTAAATTCCAGAGTTTTATTTTCCAGCGCTTG
ATTTTGTCCATCCTTGTAGATCTCGTTGGAGTTCTTCATACTCGCAACTTTCTGCGCTGAGGCATCCAGG
GATAACAGAGTGGCCATCATCATCATTGTCTGAGGGTCAACCTTATTCACCTGAGAAAGATAAGGATAGC
CAGAGGTTGTACTTTGTGTACTACTCTGTGGTTCTGTCCCACTAGTGCGGCTCATAACATCACCACTAAT
GCCGCCAAAAAGTTTGCTCAAAACATCTTCAGCAACAGAGGGCGTCACTAATGAGTGGCCTGCCGGCGGC
GTTGGTAAAGCGGTACTTTCTGTCCAACTTGCTGATGGGGCAGCGGATTTAACCAGCTGTAAATCCAGCG
CGGAAGACCCTCCAGGTTGATTAATACCTGAAGTAGTCGTAGCGGCACTGACCCCAGACATCACAGACTG
GATATCGCTATTTACATTAAGCA
Protein Sequence 
>gi|260869673|ref|YP_003236075.1| translocon EspD [Escherichia coli O111:H- str. 11128] MLNVNSDIQSVMSGVSAATTTSGINQPGGSSALDLQLVKSAAPSASWTESTALPTPPAGHSLVTPSVAEDVLSKLFGGISGDVMSRTSGTEPQSSTQSTTSGYPYLSQVNKVDPQTMMMMATLLSLDASAQKVASMKNSNEIYKDGQNQALENKTLEFKKQLEEQQKAEEKAQKSKIVGQVFGWLGVAVTAVAAIFNPALWAVVAVSATAMALQTAVDVMGDKAPQALKTAAQAFGGLSLAAGILTAGIGGVSSLMSKVGDVAGKVGSNIVKAVTTLADTLVENVASKISAVANGLTTSSRSIGTTVLNNDAANHNLLSQISSFVVENLTRQSESLSQSAKAELDKAALEVQNQANYIQSASKLISDSARVNSRIVSGRV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].