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ler from Escherichia coli O111:H- str. 11128

Victor ID 3719
Gene Name ler from Escherichia coli O111:H- str. 11128
Sequence Strain (Species/Organism) Escherichia coli O111:H- str. 11128
NCBI Gene ID 8485572
NCBI Protein GI 260869706
Locus Tag ECO111_3772
Protein Accession YP_003236108.1
Other Database IDs UniProtKB-ID: C8UFN5_ECO1A
UniRef100: UniRef100_O52122
UniRef90: UniRef90_C7BUR5
UniRef50: UniRef50_Q8VTF2
UniParc: UPI00000B3377
EMBL: AP010960
EMBL-CDS: BAI37557.1
RefSeq_NT: NC_013364.1
EnsemblGenome: EBESCG00000182854.
EnsemblGenome_TRS: EBESCT00000184230
EnsemblGenome_PRO: EBESCP00000173886
GenomeReviews: AP010960_GR
KEGG: eoi:ECO111_3772
ProtClustDB: CLSK334877
Taxonomy ID 585396
Gene Starting Position 3751192
Gene Ending Position 3751581
Gene Strand (Orientation) -
Protein Name transcription regulator Ler
DNA Sequence 
>gi|260866153:3751192-3751581 Escherichia coli O111:H- str. 11128, complete genome
GTTAAATATTTTTCAGCGGTATTATTTCTTCCTCAGTGTCCTTCACAAGAAAATCTTCTTTCTTCATTCC
ATTCAACAGTGCTTCTTTAAGCCAGCGTGGCTGTCGGCCTACGCCCGACCAGGTCTGCCCTTCTTCATTG
CGATAGTAAACACCTTTCGATGAGTTCCGGCGAGCGAGTCCATCATCAGGCACATTAGTATATCCCAGCT
CTTGTAAGGTTATATTGTAATAAGTAATCTGCTTCTGAATCGACTCAATTACACTTTGAACTTCCTGCTC
TCGCAGTCGCTTTGCTTCCTGCTGTAGAACTGCAATTTGCTCTATAAGCTGAATGTATGGACTTGTTGTA
TGTGAATTAGTTTCCATATTCATAATAAATAATCTCCGCA
Protein Sequence 
>gi|260869706|ref|YP_003236108.1| transcriptional regulator Ler [Escherichia coli O111:H- str. 11128] MRRLFIMNMETNSHTTSPYIQLIEQIAVLQQEAKRLREQEVQSVIESIQKQITYYNITLQELGYTNVPDDGLARRNSSKGVYYRNEEGQTWSGVGRQPRWLKEALLNGMKKEDFLVKDTEEEIIPLKNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ler mutants had less adhesion to HeLa cells, ler is a regulator of many virulence genes in the LEE PAI which are needed for adherence (Torres et al., 2008).
COG COG2916R, under R: General function prediction only
References
Torres et al., 2008: Torres AG, Slater TM, Patel SD, Popov VL, Arenas-Hernández MM. Contribution of the Ler- and H-NS-regulated long polar fimbriae of Escherichia coli O157:H7 during binding to tissue-cultured cells. Infection and immunity. 2008; 76(11); 5062-5071. [PubMed: 18794291].