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escN from Escherichia coli O111:H- str. 11128

Victor ID 3718
Gene Name escN from Escherichia coli O111:H- str. 11128
Sequence Strain (Species/Organism) Escherichia coli O111:H- str. 11128
NCBI Gene ID 8485567
NCBI Protein GI 260869686
Locus Tag ECO111_3752
Protein Accession YP_003236088.1
Other Database IDs UniProtKB-ID: C8UFL5_ECO1A
UniRef100: UniRef100_B8ZYA0
UniRef90: UniRef90_O85632
UniRef50: UniRef50_O85632
UniParc: UPI0001923503
EMBL: AP010960
EMBL-CDS: BAI37537.1
RefSeq_NT: NC_013364.1
EnsemblGenome: EBESCG00000181191.
EnsemblGenome_TRS: EBESCT00000183784
EnsemblGenome_PRO: EBESCP00000172180
GenomeReviews: AP010960_GR
KEGG: eoi:ECO111_3752
ProtClustDB: CLSK334788
Taxonomy ID 585396
Gene Starting Position 3737103
Gene Ending Position 3738443
Gene Strand (Orientation) -
Protein Name translocator EscN
DNA Sequence 
>gi|260866153:3737103-3738443 Escherichia coli O111:H- str. 11128, complete genome
CTCAGGCAACCACTTTGAATAGGTTTTCAATCGTTTTTTCGTAACTACTGATATCTTTGGTGCTTTGCTG
TATAAAGCTCTGAATTAATTTCCTATTTTTTATTGCCTTATCCGCTTCAGGATCTTGCCCCATCGTGTAC
TCACCAATACGAATAAGCAGCTCAACATTGTTATAAGTCGCAATAAGCTTTTTGCATTCTGCCGCCGCAC
GCAAATGCTCCGATGTAACAACGTTATGCATAACACGACTGGCACTTAAACCAATATCAATTGCAGGGAA
ATGGTTTTCCTCTGCAAGTTCTCGGGTAAGTACGATATGCCCATCAAGAATAGAGCGGACTTCATCGCCA
ATAGGATCATTAACATTATCGCTTTCTAACAACACCGTATAAATCGCGGTTATTGAACCTTTTGGCGCAG
GCCCCGCTCGCTCTAATAATTTAGGTAACGAGGAAAAAACACTCGGAGGGAATCCCCCCCTTACATCAGG
TTCTCCCGATGCAAGCCCAACATCACGCGCGGCTCGGGCATAACGAGTTACAGAATCCATCATTAATAAT
ACATTTTTACCCTGATCGCGGAAGTACTCTGCAATAGTCGTCGCCGTAAATGCGGCTTTCATCCTTTCCA
GTGCGGGGCGGTCTGACGTTGTGACGACCAGCACACATTTAGAAAGCGTGGATTGAGGTAAAAGCGCGAG
GAATTCATTTACTTCGCGACCACGTTCGCCGATAAGAGCAAGGACAATAATATCTGCGGATGCGCCATTA
CAAATCATCCCCAAAAGCGTACTTTTACCAACGCCTGAACCGGCAAAAATACCGATACGCTGCCCAATAC
CGCAAGTTAGTAACCCATCAATTGCCCTGACGCCAAGTATAAATGGCTGATCAATAACCTGCCTTAATAA
AGGATCTGGTGGTTCAGCATACAAGCTGCGTTCAAACGGAAGATAGGGAGCAGCAATATTACTCTCCATT
GGTCTGCCAATGCCATCAACAAGCCGCCCAAGTAGTGCGTCTCCAACACGAATCTTGAACTCATCCCCCT
GATAACTTAACCACTGACCACAGTACATGCCGGAAACATGCTCAAAAGGCAACAGGAAAACCTCATCTTC
ATCAATAGCGATCACCTCGGCTAAACGTTGACTGGGTTCTATCTTGTAAAAGGCGCCAATACGCGCTTTT
GGTAAACGCGCCTTAATAATCGTCCCGCCGATATTGGTAATTTTACCTTCATATCTGGTAGACGAATTTA
ATGATAATGCCGGCACAGTGCTATTGAGCACTTTCTGAATACGTGGGTATCTTTCCAATACAGAATCATG
CTCTGAAATCA
Protein Sequence 
>gi|260869686|ref|YP_003236088.1| translocator EscN [Escherichia coli O111:H- str. 11128] MISEHDSVLERYPRIQKVLNSTVPALSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFLLPFEHVSGMYCGQWLSYQGDEFKIRVGDALLGRLVDGIGRPMESNIAAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYNNVELLIRIGEYTMGQDPEADKAIKNRKLIQSFIQQSTKDISSYEKTIENLFKVVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of escN abolished pathogenicity in infant rabbits compared to wild-type EHEC (Ritchie and Waldor, 2005).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Ritchie and Waldor, 2005: Ritchie JM, Waldor MK. The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infection and immunity. 2005; 73(3); 1466-1474. [PubMed: 15731044].