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dsbA from Escherichia coli O157:H7 str. TW14359

Victor ID 3713
Gene Name dsbA from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8219479
NCBI Protein GI 254795851
Locus Tag ECSP_4913
Protein Accession YP_003080688.1
Other Database IDs UniProtKB-ID: C6UZZ3_ECO5T
UniRef100: UniRef100_P0AEG5
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI000002D10B
EMBL: CP001368
EMBL-CDS: ACT74612.1
RefSeq_NT: NC_013008.1
EnsemblGenome: EBESCG00000165598.
EnsemblGenome_TRS: EBESCT00000165777
EnsemblGenome_PRO: EBESCP00000157379
GenomeReviews: CP001368_GR
KEGG: etw:ECSP_4913
ProtClustDB: PRK10954
Taxonomy ID 544404
Gene Starting Position 4898544
Gene Ending Position 4899170
Gene Strand (Orientation) +
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|254791136:4898544-4899170 Escherichia coli O157:H7 str. TW14359, complete genome
CATGAAAAAGATTTGGCTGGCGCTGGCTGGTTTAGTTTTAGCGTTTAGCGCATCGGCGGCGCAGTATGAA
GATGGTAAACAGTACACTACCCTGGAAAAACCGGTAGCTGGCGCGCCGCAAGTGCTGGAGTTTTTCTCTT
TCTTCTGCCCGCACTGCTATCAGTTTGAAGAAGTTCTGCATATTTCTGATAATGTGAAGAAAAAACTGCC
GGAAGGCGTGAAGATGACTAAATACCACGTCAACTTCATGGGTGGTGACCTGGGCAAAGATCTGACTCAG
GCATGGGCTGTGGCGATGGCGCTGGGCGTGGAAGACAAAGTGACTGTTCCGCTGTTTGAAGGCGTACAGA
AAACCCAGACCATTCGTTCAGCATCTGATATCCGCGATGTATTTATCAACGCAGGTATTAAAGGTGAAGA
GTACGACGCGGCGTGGAACAGCTTCGTGGTGAAATCTCTGGTCGCTCAGCAGGAAAAAGCTGCAGCTGAC
GTGCAATTGCGTGGTGTTCCGGCGATGTTTGTTAACGGTAAATATCAGCTGAATCCGCAGGGTATGGATA
CCAGCAATATGGATGTTTTTGTTCAGCAGTATGCTGATACAGTGAAATATCTGTCCGAGAAAAAATA
Protein Sequence 
>gi|254795851|ref|YP_003080688.1| periplasmic protein disulfide isomerase I [Escherichia coli O157:H7 str. TW14359] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutation of dsbA led to degradation of bundilin and an absence of localized adherence to host cells in EPEC (Donnenberg et al., 1997).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Donnenberg et al., 1997: Donnenberg MS, Zhang HZ, Stone KD. Biogenesis of the bundle-forming pilus of enteropathogenic Escherichia coli: reconstitution of fimbriae in recombinant E. coli and role of DsbA in pilin stability--a review. Gene. 1997; 192(1); 33-38. [PubMed: 9224871].