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escN from Escherichia coli O157:H7 str. TW14359

Victor ID 3709
Gene Name escN from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8219249
NCBI Protein GI 254795643
Locus Tag ECSP_4683
Protein Accession YP_003080480.1
Other Database IDs UniProtKB-ID: C6UYM5_ECO5T
UniRef100: UniRef100_O85632
UniRef90: UniRef90_O85632
UniRef50: UniRef50_O85632
UniParc: UPI00000D00BB
EMBL: CP001368
EMBL-CDS: ACT74404.1
RefSeq_NT: NC_013008.1
EnsemblGenome: EBESCG00000169241.
EnsemblGenome_TRS: EBESCT00000169927
EnsemblGenome_PRO: EBESCP00000156829
GenomeReviews: CP001368_GR
KEGG: etw:ECSP_4683
ProtClustDB: CLSK334788
Taxonomy ID 544404
Gene Starting Position 4664838
Gene Ending Position 4666178
Gene Strand (Orientation) -
Protein Name LEE-encoded type III secretion system factor
DNA Sequence 
>gi|254791136:4664838-4666178 Escherichia coli O157:H7 str. TW14359, complete genome
CTCAGGCAACCACTTTGAATAGGCTTTCAATCGTTTTTTCGTAACTACTGATATCTTTGGTGCTTTGTTG
TATAAAGTTCTGAATTAATTTCCTATTTTTTATTGCCTTATCTGCTTCAGGATCTTGCCCCATCGTGTAC
TCACCAATACGAATAAGCAGCTCAACATTTTTATAAGTTGCAATAAGCTTTTTGCATTCTGCCGCCGCAC
GCAAATGCTCCGATGTAACAACGTTATGCATAACACGACTGGCACTTAAACCAATATCAATTGCAGGGAA
ATGGTTTTCCTCTGCAAGTTCTCGGGTAAGTACGATGTGCCCATCAAGAATAGAGCGGACTTCATCGCCA
ATAGGATCATTAACATTATCGCTTTCTAACAACACCGTATAAATCGCGGTTATTGAACCTTTTGGCGCAG
GCCCCGCTCGCTCTAATAATTTGGGTAACGAAGAAAAAACACTCGGAGGGAATCCCCCCCTTACATCAGG
TTCTCCCGATGCAAGCCCAACATCACGTGCGGCTCGGGCATAACGAGTTACAGAATCCATCATTAATAAT
ACATTTTTACCTTGATCGCGGAAGTACTCTGCAATAGTCGTCGCCGTAAATGCGGCTTTCATCCTTTCCA
GCGCGGGGCGGTCTGACGTTGTGACGACCAGTACACATTTAGAAAGCGTGGATTGAGGTAAGAGCGCGAG
GAATTCATTTACTTCGCGACCACGTTCGCCGATAAGAGCAAGGACAATAATATCTGCGGATGCGCCATTA
CAAATCATCCCCAAAAGCGTACTTTTACCAACGCCTGAACCAGCAAAAATACCGATACGCTGCCCAATAC
CGCAAGTTAGTAGCCCATCAATTGCCCTGACGCCAAGTATAAATGGCTGATCAATAACCTGCCTTAATAA
AGGATCTGGTGGTTCAGCATACAAGCTGCGTTCAAACGGAAGATAGGGGGCAGCAATATTACTCTCCATT
GGTCTGCCTATGCCATCAACAAGCCGCCCAAGTAGTGCGTCTCCAACACGAATCTTGAACTCATCTCCCT
GATAACTTAACCACTGACCACAGTACATGCCGGAAACATGCTCAAAAGGCAACAAGAAAACCTCATCTTC
ATCAATAGCGATCACCTCGGCTAAACGTTGACTGGGTTCTATCTTATAAAAGGCGCCAATACGCGCTTTT
GGTAAACGCGCCTTAATAATCGTCCCGCCGATATTGATAATCTTGCCTTCATATCTGGTAGACGAATTTA
ATGATAATGCCGGCACAGTGCTATTGAGCACTTTCTGAATACGTGGGTATTTTTCCAATACAGAATCATG
CTCTGAAATCA
Protein Sequence 
>gi|254795643|ref|YP_003080480.1| LEE-encoded type III secretion system factor [Escherichia coli O157:H7 str. TW14359] MISEHDSVLEKYPRIQKVLNSTVPALSLNSSTRYEGKIINIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFLLPFEHVSGMYCGQWLSYQGDEFKIRVGDALLGRLVDGIGRPMESNIAAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKNVELLIRIGEYTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKTIESLFKVVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of escN abolished pathogenicity in infant rabbits compared to wild-type EHEC (Ritchie and Waldor, 2005).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Ritchie and Waldor, 2005: Ritchie JM, Waldor MK. The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infection and immunity. 2005; 73(3); 1466-1474. [PubMed: 15731044].