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espD from Escherichia coli O157:H7 str. TW14359

Victor ID 3704
Gene Name espD from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8219236
NCBI Protein GI 254795630
Locus Tag ECSP_4670
Protein Accession YP_003080467.1
Other Database IDs UniProtKB-ID: C6UYL2_ECO5T
UniRef100: UniRef100_O85626
UniRef90: UniRef90_O85626
UniRef50: UniRef50_P71215
UniParc: UPI00000D00E7
EMBL: CP001368
EMBL-CDS: ACT74391.1
RefSeq_NT: NC_013008.1
EnsemblGenome: EBESCG00000167849.
EnsemblGenome_TRS: EBESCT00000164936
EnsemblGenome_PRO: EBESCP00000154362
GenomeReviews: CP001368_GR
KEGG: etw:ECSP_4670
ProtClustDB: CLSK334861
Taxonomy ID 544404
Gene Starting Position 4651146
Gene Ending Position 4652270
Gene Strand (Orientation) -
Protein Name secreted protein EspD
DNA Sequence 
>gi|254791136:4651146-4652270 Escherichia coli O157:H7 str. TW14359, complete genome
ATTAAATTCGGCCACTAACAATACGACTATTTACCCGTGCTGAATCGGACATCAGTTGAGAAACACTTTG
TAAATAGCTCGCCTGATTTTGTAACTCGCTTGCCGCTTTATCCAGCTCGAGCTTCGCACTCTCACCTAAG
CTTTCACTCTGTCGAGTTAAGTTTTGCACCGCGAAAGCAGCTAACTGAGACAACATTTGGAGTTGCGCAG
CCTCATTATTCAACGCAGTTGTCCCGGCAGAACGAATACCGTTCGTAACGCCCTCAGCCACTGTCGAAAT
TTTTGCAAAAACGTTTTTAACCAGCGCTTCTGCCGCCTTCTCAACGACTTTTACAACGCTTGAGCCAATT
TTGTTAGCAACATTACCAAATTTAGATAACAGTGAAGACACCCCGCCAACGCCGGCTGTCAGAATGCTTG
CGGCCATAGATATTCCGCCAAAGACCTGTGCTGCAGTCTTTAATCCCTGAGGGGCATTTTCCCCCATTAC
ATCGACTGCCGTTTGCAGTGCCATTGCTGTTGCACCAATGGCAACAACAGCCCAGAGTGCTGGGTTAAAA
ACAGCGGCAACGGCTGTTAATGCGACGCCCAACCAACCAAAGACCTGGCCAACAATTTTACTTTTTTGTG
ATTTCTCTTCGGCTTTCTGTTGTTCTTCGAGCTGTTTTTTATACTCCTGCGTTTTATTCTCCAGCGCTTT
AGTTTGCCCATCCATATAAATCTCGTTAGAGTTTTTCAGACTCGAGACTTTCTGCGCGGAAGTATCCAGG
GATAACAGAGTGACCATCATCATCATTTGCTGAGGGTCAACGGTATTCACCTGAGAGAGATAGGGATAGC
TTGTGCGCTGTGGCTCTGCCTCCTCAGTGCGACTTGTAACCTCACCACTAATACCACCAAACAATTTACT
AAGGACATCCTCAGCAGCAGAGGGCGTCACTAATGAGTGACCTGCCGGCGGCGTCGGTAAAGGGCTACTT
TCTGTCCAGCCTGCTGACGAGTTCATGGATTTAACCAGTTGTAAATCCAGCGATAAACCCGTTTCAGATT
GAGTAATACCAGAAGTACCCGAGGCGGTATTAACCCCAGACGTTACAGACAGGGTATCGTTATTTACGTT
AAGCA
Protein Sequence 
>gi|254795630|ref|YP_003080467.1| hypothetical protein EspD [Escherichia coli O157:H7 str. TW14359] MLNVNNDTLSVTSGVNTASGTSGITQSETGLSLDLQLVKSMNSSAGWTESSPLPTPPAGHSLVTPSAAEDVLSKLFGGISGEVTSRTEEAEPQRTSYPYLSQVNTVDPQQMMMMVTLLSLDTSAQKVSSLKNSNEIYMDGQTKALENKTQEYKKQLEEQQKAEEKSQKSKIVGQVFGWLGVALTAVAAVFNPALWAVVAIGATAMALQTAVDVMGENAPQGLKTAAQVFGGISMAASILTAGVGGVSSLLSKFGNVANKIGSSVVKVVEKAAEALVKNVFAKISTVAEGVTNGIRSAGTTALNNEAAQLQMLSQLAAFAVQNLTRQSESLGESAKLELDKAASELQNQASYLQSVSQLMSDSARVNSRIVSGRI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].