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HP1091

Victor ID 370
Gene Name HP1091
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899627
NCBI Protein GI 15645705
Locus Tag HP1091
Protein Accession NP_207882.1
Other Database IDs UniProtKB-ID: O25723_HELPY
UniRef100: UniRef100_O25723
UniRef90: UniRef90_Q9ZM88
UniRef50: UniRef50_Q9ZM88
UniParc: UPI00000D3199
EMBL: AE000511
EMBL-CDS: AAD08137.1
RefSeq_NT: NC_000915.1
GenomeReviews: AE000511_GR
KEGG: hpy:HP1091
NMPDR: fig|85962.1.peg.1078
TIGR: HP_1091
HOGENOM: HBG757988
OMA: FAKEFTH
ProtClustDB: CLSK496005
Taxonomy ID 85962
Gene Starting Position 1153675
Gene Ending Position 1154955
Gene Strand (Orientation) +
Protein Name alpha-ketoglutarate permease (kgtP)
DNA Sequence 
>gi|15644634:1153675-1154955 Helicobacter pylori 26695, complete genome
CATGAACCCCCAAACCGCCACCAAAAAACCCTTAAAATCCCTTTTAGCCGCTAGTTCAGGTAATTTAGTG
GAATGGTATGACTTTTACGCTTATGCGTTCTTAGCGCCTTATTTCGCTAAGGAATTTACCCACACGAACG
ACCCCACTTTAGCGCTAATCTCAGCTTTTTTAGTTTTCATGCTAGGGTTTTTCATGCGCCCTTTGGGGAG
TTTGTTTTTTGGTAAATTGGGGGATAAAAAGGGGCGTAAAACTTCTATGGTGTATTCCATTATCCTTATG
GCGCTAGGCTCTTTTTTGCTCGCATTGCTCCCCACTAAAGAAATCGTAGGGGAATGGGCGTTCTTGTTTT
TATTATTAGCCAGGCTTTTACAAGGCTTTAGCGTGGGAGGAGAATACGGCGTGGTCGCTACTTACCTCTC
TGAATTGGGCAAGAATGGCAAAAAAGGTTTTTATGGCTCTTTTCAATATGTAACTTTAGTTGGAGGGCAA
CTCTTAGCTATTTTTTCGCTCTTTATCGTTGAAAACATTTACACGCATGATCAAATCAGCGCGTTTGCTT
GGCGTTATTTATTCGCTTTAGGGGGTATATTAGCCCTACTCTCTCTTTTTTTAAGAAATATCATGGAAGA
AACTATGGATAGCAAAACAACTTCCAAAACCACTATTAAAGAAGAAACCCAAAGAGGCAGTTTAAAGGAA
TTGCTCCACCATAAAAAAGCCTTAATGATAGTCTTTGGGCTAACTATGGGAGGGAGTTTGTGTTTTTATA
CTTTTACGGTGTATTTAAAAATCTTTTTAACCAACAGCTCATCATTCAGCCCTAAAGAAAGTAGTTTCAT
CATGCTTTTAGCGCTCTCTTATTTCATCTTCTTACAACCCTTGTGTGGGATGCTTGCGGATAAAATCAAA
CGCACCCAAATGCTGATGGTTTTTGCTATCACAGGGCTTATTGTAACGCCCGTTGTCTTTTATGGTATCA
AGCATGCCACTAGCGTGTATGAAGCCCTATTTTATGAAATACTCGCATTAAGCAGCATGAGTTTTTACAC
TTGCATTGCTGGGGTCATTAAGGCGGAATTATTCCCTGAACATGTGCGAGCGCTTGGCGTGGGTCTGGCC
TATGCGATCGCGAATGCGCTTTTTGGAGGGAGCGCGAGTTATGTAGCGTTAGAGTTCAAACAACATGGTT
TTGAATGGGGGTTTGTGGGCTATGTCATGTTTAGTATTGTTATCTTTATGGTTATGGTTATCATATTCCC
TAAAAAAACCTATTTGGAATG
Protein Sequence 
>gi|15645705|ref|NP_207882.1| alpha-ketoglutarate permease [Helicobacter pylori 26695] MNPQTATKKPLKSLLAASSGNLVEWYDFYAYAFLAPYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMALGSFLLALLPTKEIVGEWAFLFLLLARLLQGFSVGGEYGVVATYLSELGKNGKKGFYGSFQYVTLVGGQLLAIFSLFIVENIYTHDQISAFAWRYLFALGGILALLSLFLRNIMEETMDSKTTSKTTIKEETQRGSLKELLHHKKALMIVFGLTMGGSLCFYTFTVYLKIFLTNSSSFSPKESSFIMLLALSYFIFLQPLCGMLADKIKRTQMLMVFAITGLIVTPVVFYGIKHATSVYEALFYEILALSSMSFYTCIAGVIKAELFPEHVRALGVGLAYAIANALFGGSASYVALEFKQHGFEWGFVGYVMFSIVIFMVMVIIFPKKTYLE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP1091 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].