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eltB

Victor ID 3691
Gene Name eltB
Sequence Strain (Species/Organism) Escherichia coli ETEC H10407
NCBI Gene ID 8571464
NCBI Protein GI 268507197
Locus Tag pEntH10407_p38
Genbank Accession AP010910
Protein Accession YP_003293996
Other Database IDs UniProtKB-ID: D0Z6T1_ECOLX
UniRef100: UniRef100_Q93V32
UniRef90: UniRef90_P13811
UniRef50: UniRef50_P32890
UniParc: UPI0000039D30
EMBL: AP010910
EMBL-CDS: BAI49222.1
RefSeq_NT: NC_013507.1
Taxonomy ID 316401
Plasmid No pEntH10407
Gene Starting Position 21347
Gene Ending Position 21721
Gene Strand (Orientation) -
Protein Name heat-labile enterotoxin B subunit
Protein pI 8.61
Protein Weight 13432.45
Protein Length 124
Protein Note ETEC_038~similar to (nr):(gi|408996|gb|AAC60441.1|), BLASTP E():2.99e-65, 100.0% identity in 124 aa overlap
DNA Sequence 
>gi|268507159:21347-21721 Escherichia coli ETEC H10407 plasmid pEntH10407, complete sequence
ACTAGTTTTCCATACTGATTGCCGCAATTGAATTGGGGGTTTTATTATTCCATACACATAATTTATCAAT
TTTGGTCTCGGTCAGATATGTGATTCTTAATGTGTCCTTCATCCTTTCAATGGCTTTTTTTTGGGAGTCT
ATATGTTGACTGCCCGGGACTTCGACCTGAAATGTTGCGCCGCTCTTAAATGTAATGATAACCATTTCTC
TTTTGCCTGCCATCGATTCCGTATATGATAGTATCTTGTCATTTATCGTATATATTTGTGTGTTGCGATA
TTCCGAACATAGTTCTGTAATAGACTGGGGAGCTCCGTATGCACATAGAGAGGATAGTAACGCCGTAAAT
AAAACATAACATTTTACTTTATTCA
Protein Sequence 
>gi|268507197|ref|YP_003293996.1| heat-labile enterotoxin B subunit [Escherichia coli ETEC H10407]
MNKVKCYVLFTALLSSLCAYGAPQSITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGATFQ
VEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Deletion mutants of eltA and eltB had decreased levels of inducing cAMP secretion in an in vitro culture system, and had less adherence to IPEC-J2 and Caco-2 cells than the wild-type ETEC (Johnson et al., 2009).
References
Johnson et al., 2009: Johnson AM, Kaushik RS, Francis DH, Fleckenstein JM, Hardwidge PR. Heat-labile enterotoxin promotes Escherichia coli adherence to intestinal epithelial cells. Journal of bacteriology. 2009; 191(1); 178-186. [PubMed: 18978047].