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eltA from Escherichia coli ETEC H10407

Victor ID 3690
Gene Name eltA from Escherichia coli ETEC H10407
Sequence Strain (Species/Organism) Escherichia coli ETEC H10407
NCBI Gene ID 8571459
NCBI Protein GI 268507198
Locus Tag pEntH10407_p39
Protein Accession YP_003293997.1
Other Database IDs UniProtKB-ID: D0Z6T2_ECOLX
UniRef100: UniRef100_P43530
UniRef90: UniRef90_P43530
UniRef50: UniRef50_P43528
UniParc: UPI0000129E44
EMBL: AP010910
EMBL-CDS: BAI49223.1
RefSeq_NT: NC_013507.1
Taxonomy ID 316401
Plasmid No pEntH10407
Gene Starting Position 21718
Gene Ending Position 22494
Gene Strand (Orientation) -
Protein Name heat-labile enterotoxin A subunit
DNA Sequence 
>gi|268507159:21718-22494 Escherichia coli ETEC H10407 plasmid pEntH10407, complete sequence
TTCATAATTCATTCCGAATTCTGTTATATATGTCAACCTCTGACTGATAGTCTGAAAATATCTGCCTCTT
AACTTTTGATTGATATTTCCTGAGATATATTGTGCTCAGATTCTGGGTCTCCTCATTACAAGTATCACCT
GTAATTGTTCTTGATGAATTTCCACAACCTTGTGGTGCATGATGAATCCAGGGTTCTTCTCTCCAAGCTT
GGTGATCCGGTGGGAAACCTGCTAATCTGTAACCATCCTCTGCCGGAGCTATATTCAGATTTCTGTAATA
CCGGTCTCTATATTCCCTGTTACGATGTAATCGTTCATCAATCACACCAAAATTAACACGATACCATCCA
TATATCTGAGAATATGGTATTCCACCTAACGCAGAAACCTCCTGTTCATATGGGTGAGGGCTGTATACGC
CTAATACATCATTAACATTAAACATATTTGGTGCTGTCGCTATAACATATATATAGTAAGTGGAATATCC
TGATAATATAGACTGTCCTGCTAAGTGAGCACTTCTCAAACTAAGAGAAGTGGAAACATATCCGTCATCA
TATCTGACAAAGCCGGTTTGTGTTCCTCTCGCGTGATCATAAAGATTAATATTCATTTGAGTTCCTCTAT
CGAAGTACTCATTATGCCCTCTGGGCATAAGACCTCCGGAACGTTTTATTTCATCTGGGGGTCTAGAGTC
AGCACGGTATAATTTGTCGCCATTTGCATATAATGGCGATGCTAATAAAATAAAAAAAATGAAAGTTATA
TTTTTCA
Protein Sequence 
>gi|268507198|ref|YP_003293997.1| heat-labile enterotoxin A subunit [Escherichia coli ETEC H10407] MKNITFIFFILLASPLYANGDKLYRADSRPPDEIKRSGGLMPRGHNEYFDRGTQMNINLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLAGQSILSGYSTYYIYVIATAPNMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYRNLNIAPAEDGYRLAGFPPDHQAWREEPWIHHAPQGCGNSSRTITGDTCNEETQNLSTIYLRKYQSKVKRQIFSDYQSEVDIYNRIRNEL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Deletion mutants of eltA and eltB had decreased levels of inducing cAMP secretion in an in vitro culture system, and had less adherence to IPEC-J2 and Caco-2 cells than the wild-type ETEC (Johnson et al., 2009).
References
Johnson et al., 2009: Johnson AM, Kaushik RS, Francis DH, Fleckenstein JM, Hardwidge PR. Heat-labile enterotoxin promotes Escherichia coli adherence to intestinal epithelial cells. Journal of bacteriology. 2009; 191(1); 178-186. [PubMed: 18978047].