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HP1082

Victor ID 369
Gene Name HP1082
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899618
NCBI Protein GI 15645696
Locus Tag HP1082
Protein Accession NP_207873.1
Other Database IDs UniProtKB-ID: O25714_HELPY
UniRef100: UniRef100_O25714
UniRef90: UniRef90_D7FF01
UniRef50: UniRef50_Q9ZM79
UniParc: UPI00000D3197
EMBL: AE000511
EMBL-CDS: AAD08127.1
RefSeq_NT: NC_000915.1
HSSP: Q9CHL8
GenomeReviews: AE000511_GR
KEGG: hpy:HP1082
NMPDR: fig|85962.1.peg.1069
TIGR: HP_1082
HOGENOM: HBG758042
OMA: VKENEAF
ProtClustDB: CLSK872343
Taxonomy ID 85962
Gene Starting Position 1140085
Gene Ending Position 1141740
Gene Strand (Orientation) -
Protein Name multidrug resistance protein (msbA)
DNA Sequence 
>gi|15644634:1140085-1141740 Helicobacter pylori 26695, complete genome
CTTAGCATTCTGTCAAACGCCCATGCTCTAATTTCACATGCTTAGTGGCTAATTTTAGCGTGCTTGGGTT
GTGCGAAATAAGAATGATCAAGCGGTTTTGTTTCAATTCTAAAATGCTTTGTTTAACGCTCTCTTCTGTG
TTATTGTCTAAAGCGGAAGTGGCTTCATCAAAGATTAAAACTTGAACGTCTTTATACAAAGCTCTTGCAA
TGGCGATTCTTTGGCGTTGGCCGCCGCTAAGATTAGCGCCAAATTCATCTAAAACGCTCTCTATCCCATG
AGGCATTTTTTCAACAAAATCTAAGGCTTGAGCTTTTTTTAGGCATTCTTTGATTTTTACCTCATCAATT
TCTAAACCATACGCCACATTTTCAGCCACGCTCCCGTTAAAAATAAACACCCTTTGAGTGACAACGCTAA
TCTTTTCTCTTAAGGATTTTTGAGTGATGCTCTCTATTTTTTGATCGTTGATGAAAATTTCGCCTTTGCT
TGGCTCATAAAGGCGTAAGATCAGATTCACTAATGAGCTTTTACCGCTCCCGCTTTCGCCCTTTAAAGCG
ATGATTTCATTTTGTTGGAACTTCAAACTAATATCGTTTAAAACATAACGCTCTTGATTGTCTAGCGTAT
AAGCCAGCCATACCTTTTTAAATTCTATGGTGTGTATGGCGTTATTTAGCGTCAATTCCCCATCAACAAT
AGCCGGCTCTCTTTCTAAAATCTCATGGATCCTGTCGCTAGCGACTAAGGCTTCTTGAAAATTAGAAACA
ATCCTAGTTAAGCGTTTAATCGGCGTATAGAGCATAAAAAGGGCCGTAATGAAAGAAAAAAACGCCCCCA
CGCTAATATGGCCTCTAATCACTTCATTCCCCCCTAAATAAATCACTAGCGCTATAGCGATTGAACCTAA
AAACTCCATTAAAGGCGAAGAAATTTCAGCCACGGCGATGTTTTTGATACCGATTTTAAAAAACGCTTCA
TTTTCTTTCACAAAAGCCTTATGCTCTAATTTTTCGCCATTAGAGATTTTAATCGCTTCCACGTTGTTAA
AAACTTCACTCAAACGAGCGGTGATTTTGGCGTTACTCTCTTGATGGGATTTAGCGAGTTTTTTAACCTT
ACGAATGATTTTACTGATAGGAATAGCAGCTAACGGCATGATGACTAACCCCACTAACGCTAATTTAGGG
CTTTGATAGATCACCACCCCCACTAACCCAACAATCGTTAGCCCCTCTCTTATGCTCTCTGAAAGGTAAT
TGGACAAACTCGCTCTAATCAAACCTATATCATTGGTGATCCTTGCGATCAATTCGCCCTTTTTCGTCCT
GTTAAAAAAATCCATTTCCATTTTAAGAAGGCTTTCTAGCATAGTGTTGCGTATTTTTTTGACAATATCA
AGCCCAATGAAGTTGGTGAAATAAGTGCCTAAATACATGCCCCCACTCTTACCCAAATACGCCAAAATCA
CTAAAAAAGGCAGGATTTTGAGCATGTGAGTGTCTTTATTGATAAAAATTTCATCTAAAGTGGGCTTGAC
TAAATAAGTCCCCCAAGCCGTGCTTAAAGCCACCACTAAAGAAGAAAATAAAACCACTATAAAACTTTTA
TAATGCTCTTTAAGGTATTTAGAATAACGCTTGAAAAAGAGTTTCA
Protein Sequence 
>gi|15645696|ref|NP_207873.1| multidrug resistance protein MsbA [Helicobacter pylori 26695] MKLFFKRYSKYLKEHYKSFIVVLFSSLVVALSTAWGTYLVKPTLDEIFINKDTHMLKILPFLVILAYLGKSGGMYLGTYFTNFIGLDIVKKIRNTMLESLLKMEMDFFNRTKKGELIARITNDIGLIRASLSNYLSESIREGLTIVGLVGVVIYQSPKLALVGLVIMPLAAIPISKIIRKVKKLAKSHQESNAKITARLSEVFNNVEAIKISNGEKLEHKAFVKENEAFFKIGIKNIAVAEISSPLMEFLGSIAIALVIYLGGNEVIRGHISVGAFFSFITALFMLYTPIKRLTRIVSNFQEALVASDRIHEILEREPAIVDGELTLNNAIHTIEFKKVWLAYTLDNQERYVLNDISLKFQQNEIIALKGESGSGKSSLVNLILRLYEPSKGEIFINDQKIESITQKSLREKISVVTQRVFIFNGSVAENVAYGLEIDEVKIKECLKKAQALDFVEKMPHGIESVLDEFGANLSGGQRQRIAIARALYKDVQVLIFDEATSALDNNTEESVKQSILELKQNRLIILISHNPSTLKLATKHVKLEHGRLTEC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP1082 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG1132V, under V: Defense mechanisms
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].