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traT from Escherichia coli (strain: EC 14, pathovar: UPEC, nat-host: Homo sapiens)

Victor ID 3687
Gene Name traT from Escherichia coli (strain: EC 14, pathovar: UPEC, nat-host: Homo sapiens)
Sequence Strain (Species/Organism) Escherichia coli (strain: EC 14, pathovar: UPEC, nat-host: Homo sapiens)
NCBI Gene ID 8381950
NCBI Protein GI 256855359
Locus Tag pEC 14_110
Protein Accession YP_003162603.1
Other Database IDs UniProtKB-ID: TRAT2_ECOLX
UniRef100: UniRef100_P32885
UniRef90: UniRef90_P15177
UniRef50: UniRef50_P15177
UniParc: UPI0000000F4C
EMBL: J01769
EMBL: X52553
EMBL-CDS: AAA26075.1
EMBL-CDS: CAA36788.1
RefSeq_NT: NC_005327.1
RefSeq_NT: NC_009133.1
RefSeq_NT: NC_011812.1
RefSeq_NT: NC_013175.1
Taxonomy ID 562
Plasmid No pEC 14_114
Gene Starting Position 101398
Gene Ending Position 102129
Gene Strand (Orientation) +
Protein Name IncF plasmid conjugative transfer surface exclusion protein TraT
DNA Sequence 
>gi|256855249:101398-102129 Escherichia coli plasmid pEC14_114, complete sequence
GATGAAAATGAAAAAATTGATGATGGTTGCACTGGTCAGTTCCACTCTGGCCCTTTCAGGGTGTGGTGCG
ATGAGCACAGCAATCAAGAAGCGTAACCTTGAGGTGAAGACTCAGATGAGTGAGACCATCTGGCTTGAAC
CCGCCAGCGAACGCACGGTATTTCTGCAGATCAAAAACACGTCTGATAAAGACATGAGTGGGCTGCAGGG
CAAAATTGCTGATGCTGTGAAAGCAAAAGGATATCAGGTGGTGACTTCTCCGGATAAAGCCTACTACTGG
ATTCAGGCGAATGTGCTGAAGGCCGATAAGATGGATCTGCGGGAGTCTCAGGGATGGCTGAACCGTGGTT
ATGAAGGCGCAGCAGTTGGTGCAGCGTTAGGTGCCGGTATTACCGGCTATAACTCAAATTCTGCCGGTGC
CACACTCGGTGTAGGCCTTGCTGCTGGTCTGGTGGGTATGGCTGCAGATGCGATGGTGGAAGATGTGAAC
TATACCATGATCACGGATGTACAGATTGCAGAGCGTACTAAGGCAACGGTGACAACGGATAATGTTGCCG
CCCTGCGTCAGGGCACATCAGGTGCGAAAATTCAGACCAGTACTGAAACAGGTAACCAGCATAAATACCA
GACCCGTGTGGTTTCAAATGCGAACAAGGTTAACCTGAAATTTGAAGAGGCGAAGCCTGTTCTCGAAGAC
CAACTGGCCAAATCAATCGCAAATATTCTCTG
Protein Sequence 
>gi|256855359|ref|YP_003162603.1| conjugal transfer surface exclusion protein TraT [Escherichia coli] MKMKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIWLEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNANKVNLKFEEAKPVLEDQLAKSIANIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: traT mutants have altered membrane permeability and are sensitive to hydrophobic antibiotics (Sukupolvi and O'Connor, 1987).
References
Sukupolvi and O'Connor, 1987: Sukupolvi S, O'Connor D. Amino acid alterations in a hydrophobic region of the TraT protein of R6-5 increase the outer membrane permeability of enteric bacteria. Molecular & general genetics : MGG. 1987; 210(1); 178-180. [PubMed: 3323837].