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ompA from Escherichia coli B str. REL606

Victor ID 3681
Gene Name ompA from Escherichia coli B str. REL606
Sequence Strain (Species/Organism) Escherichia coli B str. REL606
NCBI Gene ID 8175755
NCBI Protein GI 254161071
Locus Tag ECB_00961
Protein Accession YP_003044179.1
Other Database IDs UniProtKB-ID: C6UEU2_ECOBR
UniRef100: UniRef100_P0A911
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0000130CF0
EMBL: CP000819
EMBL-CDS: ACT38643.1
RefSeq_NT: NC_012967.1
EnsemblGenome: EBESCG00000161530.
EnsemblGenome_TRS: EBESCT00000161352
EnsemblGenome_PRO: EBESCP00000151410
GenomeReviews: CP000819_GR
KEGG: ebr:ECB_00961
ProtClustDB: PRK10808
BioCyc: ECOL413997:ECB_00961-MONOMER
Taxonomy ID 413997
Gene Starting Position 1036103
Gene Ending Position 1037143
Gene Strand (Orientation) -
Protein Name outer membrane protein A (3a;II*;G;d)
DNA Sequence 
>gi|254160123:1036103-1037143 Escherichia coli B str. REL606 chromosome, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATACCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCGGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
GATGTCCAGGTCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGTTGAACGCCCTGAGCTTTGTATGCA
CCGTTTTCAACGCTGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGGCCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|254161071|ref|YP_003044179.1| outer membrane protein A [Escherichia coli B str. REL606] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].