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hlyA from Escherichia coli O26:H-

Victor ID 3680
Gene Name hlyA from Escherichia coli O26:H-
Sequence Strain (Species/Organism) Escherichia coli O26:H-
NCBI Gene ID 8715863
NCBI Protein GI 284000230
Locus Tag pO26CRL_0109
Protein Accession YP_003377917.1
Other Database IDs UniProtKB-ID: D2WFJ7_ECOLX
UniRef100: UniRef100_A8QWG4
UniRef90: UniRef90_A1EAA3
UniRef50: UniRef50_P55129
UniParc: UPI00015E1A16
EMBL: GQ259888
EMBL-CDS: ADB20514.1
RefSeq_NT: NC_013728.1
Taxonomy ID 376724
Plasmid No pO26-CRL
Gene Starting Position 95520
Gene Ending Position 98516
Gene Strand (Orientation) +
Protein Name hemolysin A
DNA Sequence 
>gi|284000133:95520-98516 Escherichia coli O26:H- plasmid pO26-CRL, complete sequence
TATGACAGTAAATAAAATAAAGAACATTTTCAATAATGCGACATTGACTACAAAATCAGCATTTAATACA
GCATCATCAAGCGTACGTTCCGCTGGCAAAAAACTCATATTATTAATACCTGATAATTATGAAGCTCAGG
GCGTGGGTATTAATGAGTTGGTCAAAGCTGCTGATGAGCTTGGAATAGAAATACACCGTACTGAACGAGA
TGATACAGCGATTGCAAACCAGTTTTTTGGTGCAGCAGAAAAAGTTGTAGGATTAACTGAACGTGGTGTT
GCAATATTCGCACCACAACTTGACAAACTTCTGCAGAAGTATCAGAAAGTTGGGAGTAAAATAGGAAGAA
CCGCTGAAAATGTAGGTAATAATCTGGGAAAAGCCGGAACAGTTCTCTCAGCACTACAGAATTTTACGGG
GATTGCTTTATCAGGCATGGCTCTTGATGAATTGCTGAGAAAACAACGGGAAGGAGAGGATATAAGTCAG
AATGATATTGCCAAAAGTAGTATTGAACTTATTAATCAGCTTGTAGATACAGTATCAAGTATAAACAGTA
CCGTTGATTCATTTTCTGAGCAGCTTAACCAGCTTGGCTCATTTTTATCCAGTAAACCTCGCTTAAGTTC
TGTTGGTGGGAAATTACAAAATTTACCAGACCTGGGCTCCCTGGGGGATGGGCTGGATGTTGTCTCCGGA
ATTCTTTCTGCTGTATCAGCAAGCTTTATTCTGGGAAACAGTGACGCACATACAGGAACAAAAGCTGCAG
CGGGTATCGAACTGACAACTCAGGTTCTTGGAAATGTTGGTAAAGCTGTTTCGCAATATATTCTGGCTCA
GAGAATGGCACAGGGGTTATCGACAACAGCTGCAAGTGCGGGTCTGATCACATCGGCTGTTATGCTGGCT
ATCAGTCCTCTTTCTTTCCTGGCTGCTGCAGATAAATTTGAGCGAGCTAAGCAGCTTGAATCATATTCTG
AACGATTTAAAAAATTGAATTATGAAGGGGATGCTTTACTCGCAGCCTTTCATAAAGAAACCGGAGCTAT
AGATGCAGCCCTGACAACAATAAATACTGTCCTGAGTTCTGTATCTGCGGGAGTTAGTGCAGCCTCCAGT
GCATCCCTCATAGGGGCCCCGATAAGCATGCTGGTGAGTGCATTAACCGGTACGATATCTGGCATTCTGG
AAGCATCAAAACAGGCTATGTTTGAGCACGTTGCAGAGAAATTCGCTGCTCGGATCAATGAATGGGAAAA
GGAGCATGGCAAAAATTATTTTGAGAATGGCTATGACGCAAGACATGCTGCGTTTTTAGAAGACTCTCTG
TCTTTGCTTGCTGATTTTTCTCGTCAGCATGCAGTAGAAAGAGCAGTCGCAATAACCCAGCAACATTGGG
ATGAGAAGATCGGTGAACTTGCAGGCATAACCCGTAATGCTGATCGCAGTCAGAGTGGTAAGGCATATAT
TAATTATCTGGAAAATGGAGGGCTTTTAGAGGCTCAACCGAAAGAGTTTACACAACAAGTGTTTGATCCT
CAAAAAGGGACCATAGACCTTTCAACAGGTAATGTATCAAGTGTTTTGACATTTATAACACCAACATTTA
CCCCAGGAGAAGAAGTTAGAGAAAGAAAACAGAGTGGTAAATATGAATATATGACATCTCTTATTGTAAA
TGGTAAGGATACATGGTCTGTAAAAGGCATAAAAAATCATAAAGGTGTATATGATTATTCAAAATTGATT
CAGTTTGTTGAAAAGAATAACAAACACTATCAGGCGAGAATGATTTCTGAACTCGGAGATAAAGACGATG
TGGTTTATTCTGGAGCAGGCTCATCAGAAGTATTTGCTGGTGAAGGTCATGATACCGTATCTTATAATAA
GACGGATGTTGGTAAACTAACAATTGATGCAACAGGAGCATCAAAACCTGGTGAGTATATAGTTTCAAAA
AATATGTATGGTGACGTGAAGGTATTGCAGGAAGTCGTTAAGGAACAGGAGGTGTCAGTAGGGAAGCGAA
CAGAGAAAATACAATATCGTGATTTTGAATTCAGAACCGGTGGAATTCCTTATGATGTAATAGATAATCT
TCATTCTGTTGAAGAGCTCATTGGCGGAAAACATGATGATGAATTCAAAGGCGGTAAGTTTAATGATATA
TTCCATGGCGCAGATGGGAACGATTATATCGAAGGTAATTATGGTAATGATCGACTATACGGCGATGATG
GGGATGATTATATATCCGGAGGACAGGGAGACGACCAGTTATTTGGTGGTAGTGGAAACGATAAATTGAG
TGGAGGGGATGGTAATAATTATCTGACAGGAGGAAGCGGTAATGATGAGCTTCAGGCACACGGAGCTTAT
AATATTCTGTCAGGTGGTACTGGTGATGATAAACTTTATGGTGGTGGTGGTATTGATCTTCTGGATGGAG
GGGAAGGTAATGACTATCTGAATGGTGGTTTTGGTAATGATATTTATGTTTATAGGCAAAACTATGGTCA
TCATACAATTGCAGATGAAGGAGGTAAAGGAGATCGTTTGCACTTATCTGATATTAGCTTTGATGATATC
GCATTTAAGAGAGTTGGAAATGATCTTATCATGAATAAAGCCATTAATGGTGTACTTTCATTTAATGAGT
CAAATGATGTCAATGGGATAACATTTAAAAACTGGTTTGCGAAAGATGCCTCAGGAGCAGATAATCATCT
TGTTGAGGTTATAACAGATAAAGATGGTCGAGAGATAAAAGTTGATAAAATACCTCATAATAATAATGAA
CGGTCAGGTTATATAAAAGCCAGTAATATAGCATCTGAAAAAAACATGGTTAATATCACCAGTGTTGCCA
ATGATATTAATAAGATTATTTCTTCAGTTTCAGGGTTCGATTCAGGTGATGAACGATTAGCATCTTTATA
TAATTTATCCTTACATCAAAACAACACACACTCAACAACTTTAACGACAACTGTCTG
Protein Sequence 
>gi|284000230|ref|YP_003377917.1| hemolysin A [Escherichia coli O26:H-] MTVNKIKNIFNNATLTTKSAFNTASSSVRSAGKKLILLIPDNYEAQGVGINELVKAADELGIEIHRTERDDTAIANQFFGAAEKVVGLTERGVAIFAPQLDKLLQKYQKVGSKIGRTAENVGNNLGKAGTVLSALQNFTGIALSGMALDELLRKQREGEDISQNDIAKSSIELINQLVDTVSSINSTVDSFSEQLNQLGSFLSSKPRLSSVGGKLQNLPDLGSLGDGLDVVSGILSAVSASFILGNSDAHTGTKAAAGIELTTQVLGNVGKAVSQYILAQRMAQGLSTTAASAGLITSAVMLAISPLSFLAAADKFERAKQLESYSERFKKLNYEGDALLAAFHKETGAIDAALTTINTVLSSVSAGVSAASSASLIGAPISMLVSALTGTISGILEASKQAMFEHVAEKFAARINEWEKEHGKNYFENGYDARHAAFLEDSLSLLADFSRQHAVERAVAITQQHWDEKIGELAGITRNADRSQSGKAYINYLENGGLLEAQPKEFTQQVFDPQKGTIDLSTGNVSSVLTFITPTFTPGEEVRERKQSGKYEYMTSLIVNGKDTWSVKGIKNHKGVYDYSKLIQFVEKNNKHYQARMISELGDKDDVVYSGAGSSEVFAGEGHDTVSYNKTDVGKLTIDATGASKPGEYIVSKNMYGDVKVLQEVVKEQEVSVGKRTEKIQYRDFEFRTGGIPYDVIDNLHSVEELIGGKHDDEFKGGKFNDIFHGADGNDYIEGNYGNDRLYGDDGDDYISGGQGDDQLFGGSGNDKLSGGDGNNYLTGGSGNDELQAHGAYNILSGGTGDDKLYGGGGIDLLDGGEGNDYLNGGFGNDIYVYRQNYGHHTIADEGGKGDRLHLSDISFDDIAFKRVGNDLIMNKAINGVLSFNESNDVNGITFKNWFAKDASGADNHLVEVITDKDGREIKVDKIPHNNNERSGYIKASNIASEKNMVNITSVANDINKIISSVSGFDSGDERLASLYNLSLHQNNTHSTTLTTTV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in zebra fish (Wiles et al., 2009).
References
Wiles et al., 2009: Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS pathogens. 2009; 5(12); e1000697. [PubMed: 20019794].