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hlyC from Escherichia coli O26:H-

Victor ID 3679
Gene Name hlyC from Escherichia coli O26:H-
Sequence Strain (Species/Organism) Escherichia coli O26:H-
NCBI Gene ID 8715862
NCBI Protein GI 284000229
Locus Tag pO26CRL_0108
Protein Accession YP_003377916.1
Other Database IDs UniProtKB-ID: D2WFJ6_ECOLX
UniRef100: UniRef100_Q5K5Z5
UniRef90: UniRef90_Q5K5Z5
UniRef50: UniRef50_P09985
UniParc: UPI00000B3039
EMBL: GQ259888
EMBL-CDS: ADB20513.1
RefSeq_NT: NC_013728.1
Taxonomy ID 376724
Plasmid No pO26-CRL
Gene Starting Position 95003
Gene Ending Position 95518
Gene Strand (Orientation) +
Protein Name hemolysin C
DNA Sequence 
>gi|284000133:95003-95518 Escherichia coli O26:H- plasmid pO26-CRL, complete sequence
TATGAAATCTAATGCTTTTGACGTCATGGGGAAGGTTGCATGGCTATGGGCCTGTTCTCCTCTGCATAAA
AAATGGCCATTATCTGTTTTTGCTATTAATGTCATACCTGCTATTCAGACAAATCAATTTGCTCTCTTAA
TAAAGGATGAGCTTCCTGTAGCTTTTTGTAGCTGGGCCAGTTTAGATCTGGAATGTGAGGTAAAATATAT
AAATGATGTAACATCTTTGTATGCAAAAGACTGGATGTCGGGAGAAAGAAAGTGGTTTATTGACTGGATA
GCTCCATTTGGACACAACATGGAGTTATATAAATACATGAGGAAAAAGTATCCTTATGAGTTATTCAGAG
CAATAAGGTTAGATGAGAGCAGTAAAACAGGAAAAATAGCTGAATTTCATGGAGGGGGGATAGATAAAAA
ACTGGCATCAAAAATATTCAGGCAATACCATCATGAACTTATGTCTGAAGTAAAAAACAGACAAGATTTT
AATTTTAATATTGAGAAAGAAAACTA
Protein Sequence 
>gi|284000229|ref|YP_003377916.1| hemolysin C [Escherichia coli O26:H-] MKSNAFDVMGKVAWLWACSPLHKKWPLSVFAINVIPAIQTNQFALLIKDELPVAFCSWASLDLECEVKYINDVTSLYAKDWMSGERKWFIDWIAPFGHNMELYKYMRKKYPYELFRAIRLDESSKTGKIAEFHGGGIDKKLASKIFRQYHHELMSEVKNRQDFNFNIEKEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hlyC is required for the acylation and therefore activation of the toxin hemolysin which has the ability to lyse several different types of cells (Stanley et al., 1996).
References
Stanley et al., 1996: Stanley P, Koronakis V, Hardie K, Hughes C. Independent interaction of the acyltransferase HlyC with two maturation domains of the Escherichia coli toxin HlyA. Molecular microbiology. 1996; 20(4); 813-822. [PubMed: 8793877].