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pC2C203U28_p057

Victor ID 3677
Gene Name pC2C203U28_p057
Sequence Strain (Species/Organism) Clostridium botulinum
NCBI Gene ID 7636534
Uniprot ID C4B699
NCBI Protein GI 225166790
Locus Tag pC2C203U28_p057
Genbank Accession AB465552
Protein Accession YP_002650775
Other Database IDs UniProtKB-ID: C4B699_CLOBO
UniRef100: UniRef100_C4B699
UniRef90: UniRef90_D4N872
UniRef50: UniRef50_C6DXY3
UniParc: UPI00019827C8
EMBL: AB465552
EMBL: AP010934
EMBL-CDS: BAH29458.1
EMBL-CDS: BAH29550.1
RefSeq_NT: NC_012219.1
ProtClustDB: CLSK687634
Taxonomy ID 1491
Plasmid No pC2C203U28
Gene Starting Position 45459
Gene Ending Position 47624
Gene Strand (Orientation) +
Protein Name C2 toxin,component II
Protein pI 5.92
Protein Weight 76844.87
Protein Length 721
Protein Note C2P057~identical to C2 toxin(component-II) [Clostridium botulinum] (gi|3478672|ref|BAA32537.1|)
DNA Sequence 
>gi|225166733:45459-47624 Clostridium botulinum plasmid pC2C203U28, complete sequence
TATGTTAGTTTCAAAAATTGAGAACTCCGTAAAAGATTCAAATAAAAATTATTTCACAATAAACGGTTTA
ATGGGGTATTATTTTGAAAATGACTTTTTTAATTTAAGTATAATATCACCAACTTTAGATGGAAATTTAA
CTTTTAGTAAAGAGGATATTAATTCAATCTTAGGTAATAAGAGCATTAAGTCTGCAAGATGGATTGGTTT
AATAAAGCCTAGTATAACTGGAGAATATGTTTTATCAACAAATAGTTCTAATTGTAGAATTGAACTAAAT
GGTGAAATATTTAACCTATCTTTAAACACATCTAATACTGTTAATTTAATTAAAGGAAACGTTTATGACA
TCAGAATAGAACAATTAATGTCAGAGAATCAGTTATTAAAAAATTATGAAGGAATTAAGCTTTACTGGGA
AACTTCGGATATTATAAAAGAAATAATTCCTTCAGAAGTATTGTTAAAACCCAATTATAGTAATACAAAT
GAGAAATCTAAATTTATTCCTAATAATACACTGTTCTCTAATGCTAAATTAAAGGCTAATGCAAATAGAG
ATACTGATAGAGATGGTATACCTGATGAATGGGAAATTAATGGATATACGGTTATGAATCAAAAAGCTGT
AGCATGGGATGATAAATTTGCAGCTAATGGTTATAAAAAATATGTATCTAATCCTTTTAAACCTTGTACT
GCAAATGACCCATATACAGACTTTGAAAAAGTTTCAGGACAAATAGATCCATCTGTAAGTATGGTAGCAA
GAGATCCAATGATATCTGCTTATCCTATAGTTGGAGTCCAAATGGAAAGATTAGTTGTTTCTAAATCAGA
AACAATTACTGGAGATTCAACTAAGAGTATGTCTAAATCAACTAGTCATAGTAGTACTAATATTAATACT
GTTGGCGCAGAAGTTTCAGGTAGTTTACAACTTGCTGGAGGTATATTCCCTGTATTTAGCATGTCTGCTT
CAGCAAATTATTCTCACACATGGCAAAATACAAGTACAGTTGATGATACAACTGGAGAAAGTTTCTCTCA
AGGATTAAGTATAAATACTGGTGAATCCGCTTATATAAATCCTAATATTAGATATTATAATACTGGTACT
GCTCCAGTGTATAATGTTACTCCCACTACTACCATAGTAATTGATAAACAATCTGTAGCCACTATTAAGG
GACAAGAAAGCTTAATTGGGGACTATCTAAATCCTGGTGGAACCTATCCTATTATAGGAGAACCTCCTAT
GGCTTTAAATACTATGGATCAATTTAGTAGTCGTTTAATTCCGATAAATTACAATCAATTAAAAAGCATT
GATAATGGTGGAACTGTAATGTTATCGACATCCCAGTTTACTGGAAACTTTGCCAAATATAATTCCAACG
GTAATTTAGTAACTGATGGAAACAATTGGGGACCTTATTTAGGTACTATAAAAAGTACAACAGCTTCATT
AACTTTATCTTTCTCTGGTCAAACTACTCAAGTTGCTGTTGTTGCTCCTAATTTTAGTGATCCTGAAGAT
AAAACTCCTAAATTAACTTTGGAACAAGCTCTAGTTAAAGCTTTCGCACTTGAAAAGAAAAATGGTAAAT
TTTATTTTCATGGTTTAGAAATTAGTAAAAATGAAAAAATACAAGTATTTTTAGATAGTAATACAAATAA
TGATTTTGAAAATCAATTAAAAAATACAGCTGATAAAGATATTATGCATTGTATAATAAAACGTAATATG
AATATTTTAGTAAAAGTAATTACTTTTAAAGAAAATATATCCTCAATCAATATCATAAATGATACTAATT
TTGGTGTTCAATCTATGACAGGTCTTTCTAATAGATCTAAAGGACAAGATGGTATCTATAGAGCTGCTAC
AACAGCTTTTTCTTTTAAATCTAAAGAACTAAAATATCCAGAAGGTCGTTATAGAATGCGTTTTGTAATT
CAATCTTATGAACCGTTTACCTGTAACTTTAAACTCTTTAATAACCTAATATATTCTAGTTCATTTGATA
AAGGATATTATGATGAATTTTTTTACTTTTATTATAATGGCAGTAAATCTTTTTTTAATATTTCTTGTGA
TATTATAAATTCTATTAATAGGCTTTCGGGGGTTTTCTTAATAGAATTAGATAAATTAATAATATA
Protein Sequence 
>gi|225166790|ref|YP_002650775.1| C2 toxin,component II [Clostridium botulinum]
MLVSKIENSVKDSNKNYFTINGLMGYYFENDFFNLSIISPTLDGNLTFSKEDINSILGNKSIKSARWIGL
IKPSITGEYVLSTNSSNCRIELNGEIFNLSLNTSNTVNLIKGNVYDIRIEQLMSENQLLKNYEGIKLYWE
TSDIIKEIIPSEVLLKPNYSNTNEKSKFIPNNTLFSNAKLKANANRDTDRDGIPDEWEINGYTVMNQKAV
AWDDKFAANGYKKYVSNPFKPCTANDPYTDFEKVSGQIDPSVSMVARDPMISAYPIVGVQMERLVVSKSE
TITGDSTKSMSKSTSHSSTNINTVGAEVSGSLQLAGGIFPVFSMSASANYSHTWQNTSTVDDTTGESFSQ
GLSINTGESAYINPNIRYYNTGTAPVYNVTPTTTIVIDKQSVATIKGQESLIGDYLNPGGTYPIIGEPPM
ALNTMDQFSSRLIPINYNQLKSIDNGGTVMLSTSQFTGNFAKYNSNGNLVTDGNNWGPYLGTIKSTTASL
TLSFSGQTTQVAVVAPNFSDPEDKTPKLTLEQALVKAFALEKKNGKFYFHGLEISKNEKIQVFLDSNTNN
DFENQLKNTADKDIMHCIIKRNMNILVKVITFKENISSINIINDTNFGVQSMTGLSNRSKGQDGIYRAAT
TAFSFKSKELKYPEGRYRMRFVIQSYEPFTCNFKLFNNLIYSSSFDKGYYDEFFYFYYNGSKSFFNISCD
IINSINRLSGVFLIELDKLII
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: C2 toxin is the prototype of actin-ADP-ribosylating toxins, and produces enterotoxic effects in humans (Aktories and Barth, 2004)
Predicted Interacting Host Protein A6NF34; A6NMZ7; A6NNA4; A6PVD9; A8TX70; B0UXW4; B2CPU0; B2RTV5; B4DQI1; B4E1Z4; B5MD45; B7ZKJ8; C9J2H1; C9J6F5; C9JE82; C9JGM2; C9JH44; C9JHE6; C9JNG9; C9JVC9;
D6RGG3; E7EMF1; E7EN67; E7ENL6; E7ESP4; E7ET33; E7ETN3; E9PAL5; E9PB77; E9PBN8; E9PCV6; E9PDZ0; E9PHD9; F5GXQ1; F5GY13; F5GZK2; F5H7E1; F8W6Y7; F8W8G8; G3V4C4;
G3V5V4; G3V5X3; G5E9D8; H0Y393; H0Y3H6; H0Y4P7; H0Y5N9; H0Y868; H0Y935; H0Y991; H0Y9T2; H0YBB2; H0YBJ4; H0YBN2; H0YBU5; H0YJW4; H3BN02; H3BPS2; H3BSV1; H3BUA0;
H7C0L5; H7C0M5; H7C587; H7C5H1; I3L392; J3KN08; J3KQ60; J3KQM2; J3QLP3; J3QRR0; J3QT83; O00339; O15232; O43405; O75578; O95460; P00751; P04275; P06681; P11215;
P12109; P12110; P12111; P17301; P19823; P19827; P20701; P20702; P21941; P38570; P54289; P56199; P58335; Q02388; Q05707; Q06033; Q13349; Q14624; Q2UY09; Q4G0W3;
Q4LDE5; Q5GFL6; Q5T985; Q6L9W6; Q6PCB0; Q6UXI7; Q76KP1; Q86UX2; Q86WI1; Q8NFW1; Q96IU6; Q96P44; Q99715; Q9H6X2; Q9NY47; Q9P218; Q9UKX5
References
Aktories and Barth, 2004: Aktories K, Barth H. The actin-ADP-ribosylating Clostridium botulinum C2 toxin. Anaerobe. 2004; 10(2); 101-105. [PubMed: 16701506].