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pC2C203U28_p056

Victor ID 3676
Gene Name pC2C203U28_p056
Sequence Strain (Species/Organism) Clostridium botulinum
NCBI Gene ID 7636529
Uniprot ID C4B698
NCBI Protein GI 225166789
Locus Tag pC2C203U28_p056
Genbank Accession AP010934
Protein Accession YP_002650774
Other Database IDs UniProtKB-ID: C4B698_CLOBO
UniRef100: UniRef100_C4B698
UniRef90: UniRef90_C4B698
UniRef50: UniRef50_Q45847
UniParc: UPI00019827C7
EMBL: AB465552
EMBL: AB465553
EMBL: AB465554
EMBL: AP010934
EMBL-CDS: BAH29457.1
EMBL-CDS: BAH29471.1
EMBL-CDS: BAH29485.1
EMBL-CDS: BAH29549.1
RefSeq_NT: NC_012219.1
ProtClustDB: CLSK2546845
Taxonomy ID 1491
Plasmid No pC2C203U28
Gene Starting Position 43918
Gene Ending Position 45213
Gene Strand (Orientation) +
Protein Name C2 toxin,component I
Protein pI 4.83
Protein Weight 47344.07
Protein Length 431
Protein Note C2P056~identical to C2 toxin(component-I) [Clostridium botulinum] (gi|3478671|ref|BAA32536.1|)
DNA Sequence 
>gi|225166733:43918-45213 Clostridium botulinum plasmid pC2C203U28, complete sequence
TATGCCAATAATAAAAGAACCCATTGACTTTATCAATAAACCTGAATCTGAAGCCCAAAAATGGGGCAAA
GAAGAAGAAAAACGTTGGTTTACGAAATTAAATAATCTTGAAGAAGTAGCCGTAAATCAACTTAAAACTA
AGGAAGATAAAACAAAAATAGATAATTTTTCTACAGACATTTTATTTTCTTCATTAACTGCAATAGAAAT
TATGAAAGAAGACGAAAATCAAAATCTTTTTGATGTTGAAAGAATTAGAGAAGCACTTTTAAAAAATACT
TTAGATAGAGAAGTTATAGGCTATGTAAATTTTACACCTAAAGAGCTTGGAATTAATTTTTCTATAAGAG
ATGTAGAATTAAATAGAGATATATCAGATGAAATTTTAGATAAAGTTAGACAGCAAATAATAAATCAAGA
ATATACTAAATTTTCATTTGTATCATTAGGGTTAAATGACAACAGCATCGATGAGAGTATACCAGTTATT
GTGAAAACTAGAGTTCCAACAACGTTTAATTATGGTGTTCTTAATAATAAAGAAACAGTATCATTATTAT
TAAATCAAGGTTTTTCTATAATTCCTGAGTCAGCTATTATAACTACTATAAAAGGAAAAGACTATATATT
AATAGAAGGAAGTCTTAGTCAAGAGCTTGATTTCTATAATAAAGGATCAGAAGCTTGGGGAGAAAAAAAT
TATGGTGATTATGTTTCAAAACTTTCCCAGGAACAATTAGGTGCTTTAGAAGGATATCTGCATTCAGATT
ATAAAGCTATTAATAGTTATTTAAGAAATAATAGAGTTCCAAATAATGACGAGCTTAATAAAAAAATTGA
ATTAATAAGTTCTGCTCTATCTGTAAAGCCAATACCCGAAACATTAATAGCATATAGAAGAGTAGATGGT
ATTCCATTCGATTTACCTTCTGATTTTTCCTTTGATAAAAAAGAAAATGGTGAAATAATAGCTGATAAAC
AAAAATTAAACGAGTTTATAGATAAATGGACTGGAAAAGAAATTAAAAATTTATCATTTTCTAGTACTTC
TCTTAAATCCACCCCATTATCATTTAGTAAATCTCGTTTTATATTTAGATTGCGTTTAAGTGAAGGGACC
ATTGGAGCATTTATTTATGGGTTTTCTGGATTTCAAGATGAACAAGAAATTCTTTTGAATAAGAATTCTA
CTTTCAAGATATTTAGAATAACTCCAATAACTTCAATAATTAATAGAGTTACTAAAATGACTCAGGTAGT
AATTGATGCTGAAGTTATACAAAATAAAGAGATTTA
Protein Sequence 
>gi|225166789|ref|YP_002650774.1| C2 toxin,component I [Clostridium botulinum]
MPIIKEPIDFINKPESEAQKWGKEEEKRWFTKLNNLEEVAVNQLKTKEDKTKIDNFSTDILFSSLTAIEI
MKEDENQNLFDVERIREALLKNTLDREVIGYVNFTPKELGINFSIRDVELNRDISDEILDKVRQQIINQE
YTKFSFVSLGLNDNSIDESIPVIVKTRVPTTFNYGVLNNKETVSLLLNQGFSIIPESAIITTIKGKDYIL
IEGSLSQELDFYNKGSEAWGEKNYGDYVSKLSQEQLGALEGYLHSDYKAINSYLRNNRVPNNDELNKKIE
LISSALSVKPIPETLIAYRRVDGIPFDLPSDFSFDKKENGEIIADKQKLNEFIDKWTGKEIKNLSFSSTS
LKSTPLSFSKSRFIFRLRLSEGTIGAFIYGFSGFQDEQEILLNKNSTFKIFRITPITSIINRVTKMTQVV
IDAEVIQNKEI
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: C2 toxin is the prototype of actin-ADP-ribosylating toxins and produces enterotoxic effects in humans (Aktories and Barth, 2004)
Predicted Interacting Host Protein A4D1S5; A6NDJ8; A6NIZ1; A8MSP2; A8MTC6; A8MXF6; A8MYQ9; A8MZI4; B1AH58; B1AH77; B1AH78; B1AH79; B1AH80; B2RAA6; B4DEK7; B4DJA5; B4DJW2; B4DMK0; B4DQU5; B4DU82;
B4DV51; B4E040; B5MDF5; B7Z337; B7Z3L0; B7Z5Z2; B7Z8M7; B7ZB78; B7ZBD4; B7ZBD5; C9IZZ0; C9J0T6; C9J1T2; C9J4S4; C9J4V0; C9J592; C9J6B1; C9J7D1; C9J8Q6; C9J8S3;
C9J931; C9JB90; C9JBG0; C9JFM7; C9JJQ5; C9JNR4; C9JPE8; C9JPP2; C9JQB3; C9JQQ1; C9JRM1; C9JU14; C9JX21; C9JXM3; C9JY26; C9JYR1; D6R935; D6RA52; D6RFW3; D6RG23;
E5RFZ3; E5RI44; E7END7; E7ES60; E7ESV4; E7ETK2; E7ETU3; E7EWW3; E9PBQ0; E9PBU2; E9PE37; E9PE51; E9PEI7; E9PFH1; E9PI18; E9PIG5; E9PJQ5; E9PK85; E9PKL7; E9PL56;
E9PLA2; E9PLD0; E9PLM3; E9PMC8; E9PMJ1; E9PN11; E9PNB9; E9PQ07; E9PQ87; E9PQH6; E9PQK5; E9PRF7; E9PRX0; E9PS06; F2Z2T3; F2Z3J7; F5GWE9; F5GWU8; F5GX61; F5GX62;
F5GXB1; F5GY21; F5GY94; F5GYB5; F5GYH7; F5GYR1; F5GZ09; F5GZG1; F5H004; F5H018; F5H077; F5H0B7; F5H157; F5H252; F5H2U5; F5H3K7; F5H491; F5H4H0; F5H500; F5H686;
F5H6R7; F5H7Y6; F5H823; F6U784; F8VPW9; F8VSF8; F8VUA5; F8VVK3; F8VVZ0; F8VWU4; F8W1T5; F8W8H5; F8WAG1; F8WBC0; F8WCY6; F8WD79; F8WDC7; F8WET9; F8WF50; G3V196;
G3V476; G3V4H1; G3V4K2; G3V562; G3V5T7; G5E9P3; G5EA41; H0Y6C7; H0Y6T8; H0Y8R9; H0Y9G4; H0Y9S6; H0YD31; H0YDB7; H0YDK7; H0YEA4; H0YFC6; H0YFJ5; H0YGL6; H0YHG7;
H0YL94; H0YLJ8; H0YMN7; H0YNE9; H3BME4; H3BMG6; H3BMH2; H3BN38; H3BN55; H3BNV8; H3BPA5; H3BS49; H3BSC1; H3BTC6; H3BU81; H3BUD9; H3BUX0; H3BVH7; H7BXP1; H7BXZ6;
H7BYW1; H7C0Y7; H7C0Z1; H7C125; H7C1P7; H7C3P7; I3L178; I3L2C6; J3KQE5; J3KQP6; J3KQW8; J3KR73; J3KSC4; J3QLC6; J3QLK0; J3QR51; J3QSF4; K7EIF2; K7EJ38; K7EMR8;
K7EN06; K7ENY4; K7ERG2; K7ERI8; K7ERQ8; K7ES41; M0R0X1; M0R1E0; M0R257; M0R2D0; M0R377; O00194; O00212; O14807; O14966; O75628; O94844; O95057; O95661; O95716;
O95755; P01111; P01112; P01116; P08134; P0C0E4; P10114; P10301; P11233; P11234; P15153; P17081; P20336; P20337; P20338; P20339; P20340; P51148; P51149; P51151;
P51153; P51157; P51159; P52198; P55040; P55042; P57729; P57735; P59190; P60763; P60953; P61006; P61018; P61019; P61020; P61026; P61106; P61224; P61225; P61586;
P61587; P62070; P62491; P62745; P62820; P62826; P62834; P63000; P84095; Q12829; Q13636; Q13637; Q14088; Q14964; Q15286; Q15382; Q15669; Q15771; Q15907; Q53RZ3;
Q5HYI8; Q5JR05; Q5JR06; Q5JR07; Q5JR08; Q5JT25; Q5JYX0; Q5W0J0; Q6IQ22; Q6MZH2; Q6MZX6; Q6PIK3; Q6PJZ0; Q6T310; Q6ZS74; Q7L0Q8; Q7Z444; Q7Z6P3; Q86YS6; Q8IXI1;
Q8IXI2; Q8IYK8; Q8IZ41; Q8N4Z0; Q8TAI7; Q8WUD1; Q8WVF3; Q8WXH6; Q92730; Q92737; Q92928; Q92930; Q92963; Q969Q5; Q96A58; Q96AH8; Q96AX2; Q96D21; Q96DA2; Q96E17;
Q96HU8; Q96L33; Q96S21; Q96S79; Q99578; Q9BPW5; Q9BW83; Q9BYZ6; Q9BZG1; Q9H082; Q9H0N0; Q9H0T7; Q9H0U4; Q9H4E5; Q9H628; Q9H7X7; Q9HBH0; Q9NP72; Q9NP90; Q9NRW1;
Q9NX57; Q9NYN1; Q9NYR9; Q9NYS0; Q9NZQ0; Q9UBK7; Q9UL25; Q9UL26; Q9ULC3; Q9ULW5; Q9UNT1; Q9Y272; Q9Y3L5
References
Aktories and Barth, 2004: Aktories K, Barth H. The actin-ADP-ribosylating Clostridium botulinum C2 toxin. Anaerobe. 2004; 10(2); 101-105. [PubMed: 16701506].