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acpB from Bacillus anthracis str. CDC 684

Victor ID 3663
Gene Name acpB from Bacillus anthracis str. CDC 684
Sequence Strain (Species/Organism) Bacillus anthracis str. CDC 684
NCBI Gene ID 7780535
NCBI Protein GI 227811374
Locus Tag BAMEG_B0065
Protein Accession YP_002808736.1
Other Database IDs UniProtKB-ID: C3L4U5_BACAC
UniRef100: UniRef100_C3L4U5
UniRef90: UniRef90_Q9RMX9
UniRef50: UniRef50_Q9RMX9
UniParc: UPI0001633EA5
EMBL: CP001214
EMBL-CDS: ACP11988.1
RefSeq_NT: NC_012577.1
EnsemblGenome: EBBACG00000119929.
EnsemblGenome_TRS: EBBACT00000123578
EnsemblGenome_PRO: EBBACP00000119578
GenomeReviews: CP001214_GR
KEGG: bah:BAMEG_B0065
ProtClustDB: CLSK862250
Taxonomy ID 568206
Plasmid No pX02
Gene Starting Position 47347
Gene Ending Position 48795
Gene Strand (Orientation) -
Protein Name capsule synthesis trans-acting positive regulator AcpB
DNA Sequence 
>gi|227811309:47347-48795 Bacillus anthracis str. CDC 684 plasmid pX02, complete sequence
ACTAACCATCTTGTAAATCTAGATAATACTGTATATTGGTGTAATCGCGTTCTGTAGGGATAGAATTAAC
ACATATAATAGGGGTTGAACCTAAGTCAAGAGGTATTGTTGAAATAATAAAGTCAGCATTAACATCGTGA
TCACTCTTTTTAGCAAAAAAAACAGTTGAAATTTGTATTTTATCACCAAACCTTTTTGCCAAAGTAGCAG
CTAGATACTCTGCCCAACTTTCACTTTCTCCTGTGACAAGTAATACCTTTTTATAATTACTAGTATAACG
AAGCCTACTTGCCTCTATATACATTGTAACTTTTGCAATTTCTTCAACAGATACATAGTCTGCTATCTCA
TTTTTTTTGACAAATTCTGTGTATACTTCCTTTACTGCTGAGAAGGTTTCCGAATGTTCAGTTTGCATAT
ACTGTATAGTTTGTTTTTGCGGCCTTTCAAACATACATAGGTATTGTAAATGATATATCGTTCTTTTAAA
ATAGTCGACTAATGCAAAAATAAATTCTTCATCACTTATTAGATCTACTTTTAATTTTTCTTCTAATGAA
TTGATAAAGTCTTTAACTAACTCATAAATCGATAAATTTCCTTCCTTAAAATATTGAACACTCTCCTCTT
TCTCTTTATTTATATCTTTGTAAACATATTTAGAACTCTTAATACTAATTGTTAACAAAATCTTATCTTG
TACTGTTAAGCTAACACCAAATTCACGTTCTAGCTTTTCGAATATTCTTCCTATTTTCACATAATCGGGA
GTTTCTGTATTAAAGTATAAAAACTTTCTATTTAATTGAACTTTGTATCCCTGTTGCTTTCGTTTTAATA
AAATTGCTATAAAAAAAGATAAATGCCTTTTAGAAACCACATGTAATGAGATTCCTAATGATTCTTCAAG
AGTTCCAAGGTATTGAAAAATAACTTCTTTTTTCAATTTTTCAAATGGCCACTCTGTATCATTATAAGAT
TTTAAATACAGATCCAAATACATTATCATGATTCGAACTTCATCCCCCTCAAGTCTAAGAGGTTTCTTAC
GAAGCTTCAAACCAAATTTTTTAAGATAATTCTCTACTCTTTTTAATGCAGGTAGAATAGATGGGACTTG
TATATATAATCTCTCTGCTAAGGTAGCAATTGTTTTTGTTTCTCTCTCAAATAAATGTTGTAATATCCGG
AAAGTTAAAGATTCCCGAAAAAGTAAGAAAGTAATTTCATTTCTATGTTTATTATAGGGTAGATAAATTC
TAACTCCCTTTCCCTTTTTTATTTTTATATGCCAGTCTTCAGGTAAAAAATCTTTGATAAATGAAATATC
TTTCATAATCGTTTTGTTACAACATCTTAAAATTTTAGAAATTTCAATAGTTGTAAACCATTTTTCTTCG
CTTGTAATTATTTCTAAGATTTGGATTTGTCTTTTTATATCTTTTTCCA
Protein Sequence 
>gi|227811374|ref|YP_002808736.1| capsule synthesis trans-acting positive regulator AcpB [Bacillus anthracis str. CDC 684] MEKDIKRQIQILEIITSEEKWFTTIEISKILRCCNKTIMKDISFIKDFLPEDWHIKIKKGKGVRIYLPYNKHRNEITFLLFRESLTFRILQHLFERETKTIATLAERLYIQVPSILPALKRVENYLKKFGLKLRKKPLRLEGDEVRIMIMYLDLYLKSYNDTEWPFEKLKKEVIFQYLGTLEESLGISLHVVSKRHLSFFIAILLKRKQQGYKVQLNRKFLYFNTETPDYVKIGRIFEKLEREFGVSLTVQDKILLTISIKSSKYVYKDINKEKEESVQYFKEGNLSIYELVKDFINSLEEKLKVDLISDEEFIFALVDYFKRTIYHLQYLCMFERPQKQTIQYMQTEHSETFSAVKEVYTEFVKKNEIADYVSVEEIAKVTMYIEASRLRYTSNYKKVLLVTGESESWAEYLAATLAKRFGDKIQISTVFFAKKSDHDVNADFIISTIPLDLGSTPIICVNSIPTERDYTNIQYYLDLQDG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: acpB mutant is attenuated in mice (Drysdale et al., 2005).
COG COG3711K, under K: Transcription
References
Drysdale et al., 2005: Drysdale M, Heninger S, Hutt J, Chen Y, Lyons CR, Koehler TM. Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax. The EMBO journal. 2005; 24(1); 221-227. [PubMed: 15616593].