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atxA from Bacillus anthracis str. CDC 684

Victor ID 3662
Gene Name atxA from Bacillus anthracis str. CDC 684
Sequence Strain (Species/Organism) Bacillus anthracis str. CDC 684
NCBI Gene ID 7780750
NCBI Protein GI 227811569
Locus Tag BAMEG_A0144
Protein Accession YP_002811580.1
Other Database IDs UniProtKB-ID: C3LLB8_BACAC
UniRef100: UniRef100_Q44636
UniRef90: UniRef90_Q44636
UniRef50: UniRef50_Q44636
UniParc: UPI0000001330
EMBL: CP001216
EMBL-CDS: ACP17829.1
RefSeq_NT: NC_012579.1
EnsemblGenome: EBBACG00000119650.
EnsemblGenome_TRS: EBBACT00000118696
EnsemblGenome_PRO: EBBACP00000117317
GenomeReviews: CP001216_GR
KEGG: bah:BAMEG_A0144
ProtClustDB: CLSK862250
Taxonomy ID 568206
Plasmid No pX01
Gene Starting Position 128087
Gene Ending Position 129514
Gene Strand (Orientation) -
Protein Name anthrax toxin expression trans-acting positive regulator
DNA Sequence 
>gi|227811427:128087-129514 Bacillus anthracis str. CDC 684 plasmid pX01, complete sequence
TTTATATTATCTTTTTGATTTCATGAAAATCTCTTTCTGTAGGAAATTCCGAAATTTGTACAATAGGTAT
ATTTTTTATAGGTAAGTTAACATTAGAAATAATAATATCTATCTCCATGTCTTGGAGTGATTCGTTAGTT
AAATTTATAATAGTGTTTCTTACAATTTTAATAAGTCCATTATAACGTTTTTCAAGCAGTGCAGATATAT
ACTCTCGATGTATACATCCTTGTGAGGTGTATACATATATTTTTTTCGGGTTATTTTTAAATAGCATACG
TTGAGTTTCAAAATGCATTGTTAATAATGAAATTTCATAGCAGTCGAAATGGGAGTATACTGTATAGTTT
AAATTACTAATGCATTCTTGAATTGTATTAAATGTATTTGGATGACGCTGTTTTATATGCCTTATAAATT
TTATATTATAATTATAATATTGAATAAAGTTTTTATCTAATGCTTTTTTTATGATTAGAACAACATATGT
TAAAAAAGATTCATCATAATTTATCCCAAGTTGTAATTTATGTTCAATTCCTTTGGTAATTTCTTTAGCC
AAAGGCATAATTGTTTTTTTGTAGGAAGTTAATGTTTTATTGCTGTCTGTGGTAATAGAATTTCCAAGAG
ATAAAAGTAGTGCAAGGGCTAAAAATGAAATCTCAGTTTCATGTAATGTAACGCCGAAAGAGTTTTGTAG
CTCTGAGGTTATAGACGCTACTGTTTTATAATGATCATCATTTTTATTTACTAAAATAAGTCCACTTACA
TTATCTATTGTATTTCCTGATAGTAATCTGGAGATTGTTATAGCGAACAACACACACAATTTGTGTTTTG
AATAGGTGTACATTTGTACATTTAAAATTTTTTCCATTTTATTAATTAAATCAGTGATATTTTGTTTATT
AATATAGGGAAACGGCCAATAATCATTTGGAATATTGCAATATAACCTTAACATAAATACGCGGACATCT
TGTTCTCTTCCCGATATTTCTAGAGGTTTTTTTTTGATATTTAAATGACTGGATTGTATATCATAATTTA
TTTGATTAATAATTGGGTATAAAGCTCCTACTTGTAAGTGGAGTTTTTGAGCTAAGGATTGCATACTGTT
TTTTTTGAATACAAGTTCTTCGCAAATTTGAAGATTTAGTGATTTTCTTAAAATTTTTGATTCAACAAAG
GAAAGGGATTCATTTAATGGTTTTTTTAGATAAATTCCTTTTCCTTTTTGAACAAGTAAATTCCAAGATG
GAGGAATTTCGTCTTCTAATAATTTTAAATATTTTCGGACTGTTTTATCTGCGACCTGTAGATAATCAGA
TAATTCTTTAATTGTAAACCATCTATTTTGTTCATTGATAAAGTGTAGTAAATTAATTAATCTTATATGT
TCCTTTTCGATGGATATCGGTGTTAGCA
Protein Sequence 
>gi|227811569|ref|YP_002811580.1| anthrax toxin expression trans-acting positive regulator [Bacillus anthracis str. CDC 684] MLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFKKNSMQSLAQKLHLQVGALYPIINQINYDIQSSHLNIKKKPLEISGREQDVRVFMLRLYCNIPNDYWPFPYINKQNITDLINKMEKILNVQMYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYKTVASITSELQNSFGVTLHETEISFLALALLLSLGNSITTDSNKTLTSYKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIKKALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYSHFDCYEISLLTMHFETQRMLFKNNPKKIYVYTSQGCIHREYISALLEKRYNGLIKIVRNTIINLTNESLQDMEIDIIISNVNLPIKNIPIVQISEFPTERDFHEIKKII
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: atxA mutant is avirulent in mice (Koehler, 2002).
COG COG3711K, under K: Transcription
References
Koehler, 2002: Koehler TM. Bacillus anthracis genetics and virulence gene regulation. Current topics in microbiology and immunology. 2002; 271; 143-164. [PubMed: 12224521].