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clpX from Bacillus anthracis str. CDC 684

Victor ID 3656
Gene Name clpX from Bacillus anthracis str. CDC 684
Sequence Strain (Species/Organism) Bacillus anthracis str. CDC 684
NCBI Gene ID 7784922
NCBI Protein GI 227817253
Locus Tag BAMEG_4740
Protein Accession YP_002817262.1
Other Database IDs UniProtKB-ID: CLPX_BACAC
UniRef100: UniRef100_C3P9F7
UniRef90: UniRef90_C3P9F7
UniRef50: UniRef50_Q833M7
UniParc: UPI0000167644
EMBL: CP001215
EMBL-CDS: ACP12283.1
RefSeq_NT: NC_012581.1
EnsemblGenome: EBBACG00000123859
EnsemblGenome_TRS: EBBACT00000120216
EnsemblGenome_PRO: EBBACP00000117248
GenomeReviews: CP001215_GR
KEGG: bah:BAMEG_4740
ProtClustDB: PRK05342
Taxonomy ID 568206
Gene Starting Position 4282452
Gene Ending Position 4283711
Gene Strand (Orientation) -
Protein Name ATP-dependent Clp protease, ATP-binding subunit ClpX
DNA Sequence 
>gi|227812678:4282452-4283711 Bacillus anthracis str. CDC 684, complete genome
ATTATGCAGATGTTTTTGTATCAAGTACAGTACCGTCTTGTAACACCAATTTTGGTGCTGCATTATCAGC
TACTGTTTCTTTTGTAAGAATACACTTCTCGATATCTTTGCGAGATGGTAGCTCGAACATTACCTCAAGC
ATTAAGCCTTCAATAATAGAACGAAGTCCACGAGCACCTGTTTTACGTTCAATTGCTTTTTTCGCAATTT
CAATTAGTGCACCTTCTTCAAACTCTAACTCAACATCGTCAAGCTCCAATAGTTTTTGGAATTGCTTAAC
AAGTGCATTTTTCGGTTTCGTTAAAATATCAACAAGAGCATCTTCATCAAGTGGCTCTAGGTTCGCAATA
ACTGGAAGACGACCGATAAACTCTGGAATTAAACCAAATCTTAAAAGGTCTTCTGGTAATACGTGAGATA
AAACATGCTTCTCATTTACATCAGCATTTTTCTTCTCAGAACCAAATCCAATTACCTTTTCACCAAGACG
GCGTTTAATAATTGGCTCGATGCCATCAAACGCTCCACCACAGATGAATAAGATATTCGTTGTATCAATT
TGAATAAACTCTTGGTGCGGATGCTTACGACCACCTTGAGGTGGAACGCTTGCTACAGTACCTTCTAAAA
TTTTCAGAAGTGCCTGCTGCACACCTTCACCAGATACATCACGTGTAATTGATGGATTTTCGGACTTACG
TGCCACTTTATCAATCTCATCAATATAAATGATTCCTTTTTCCGCTTTTTCTACATCATAATCCGCTGCT
TGGATTAATTTAAGTAAGATGTTTTCTACATCTTCCCCAACGTATCCAGCTTCAGTTAAAGATGTTGCGT
CCGCGATTGCAAATGGAACATTTAAAATACGCGCTAACGTTTGTGCCAGTAATGTTTTACCACTACCTGT
TGGCCCGATAAGTGCGATATTACTCTTCGCTAATTCTACATCATCAATTTTGCTGTTAGAATTAATGCGT
TTGTAATGGTTATATACCGCTACCGCTAGTGCTTTTTTCGCGTTATCTTGTCCGATGACATACTCATCTA
AAATTTCACGAATTTCTACCGGTTTCGGTACATCTTTGAATTCTACTTCTTCGTCTTTCGCAAGCTCCTC
TTGTACAATTTCAGTACAAAGTTCGATACACTCGTCACAAATGTAAACACCTGGACCTGCAACTAACTTT
CGGACTTGTGTTTGTGTTTTACCACAGAAAGAACATTTTAATTGCCCTTTTTCATCATTAAATTTAAACA
Protein Sequence 
>gi|227817253|ref|YP_002817262.1| ATP-dependent protease ATP-binding subunit ClpX [Bacillus anthracis str. CDC 684] MFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: clpX deletion mutant is attenuated in mice (McGillivray et al., 2009).
COG COG1219O, under O: Posttranslational modification, protein turnover, chaperones
References
McGillivray et al., 2009: McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. Journal of innate immunity. 2009; 1(5); 494-506. [PubMed: 20375606].