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acpB from Bacillus anthracis str. A0248

Victor ID 3646
Gene Name acpB from Bacillus anthracis str. A0248
Sequence Strain (Species/Organism) Bacillus anthracis str. A0248
NCBI Gene ID 7847529
NCBI Protein GI 229599687
Locus Tag BAA_B0065
Protein Accession YP_002860667.1
Other Database IDs UniProtKB-ID: C3NZ82_BACAA
UniRef100: UniRef100_Q9RMX9
UniRef90: UniRef90_Q9RMX9
UniRef50: UniRef50_Q9RMX9
UniParc: UPI0000001346
EMBL: CP001597
EMBL-CDS: ACQ45903.1
RefSeq_NT: NC_012655.1
EnsemblGenome: EBBACG00000126067.
EnsemblGenome_TRS: EBBACT00000130148
EnsemblGenome_PRO: EBBACP00000123806
GenomeReviews: CP001597_GR
KEGG: bai:BAA_B0065
ProtClustDB: CLSK862250
Taxonomy ID 592021
Plasmid No pXO2
Gene Starting Position 49970
Gene Ending Position 51418
Gene Strand (Orientation) -
Protein Name capsule synthesis trans-acting positive regulator AcpB
DNA Sequence 
>gi|229599623:49970-51418 Bacillus anthracis str. A0248 plasmid pXO2, complete sequence
ACTAACCATCTTGTAAATCTAGATAATACTGTATATTGGTGTAATCGCGTTCTGTAGGGATAGAATTAAT
ACATATAATAGGGGTTGAACCTAAGTCAAGAGGTATTGTTGAAATAATAAAGTCAGCATTAACATCGTGA
TCACTCTTTTTAGCAAAAAAAACAGTTGAAATTTGTATTTTATCACCAAACCTTTTTGCCAAAGTAGCAG
CTAGATACTCTGCCCAACTTTCACTTTCTCCTGTGACAAGTAATACCTTTTTATAATTACTAGTATAACG
AAGCCTACTTGCCTCTATATACATTGTAACTTTTGCAATTTCTTCAACAGATACATAGTCTGCTATCTCA
TTTTTTTTGACAAATTCTGTGTATACTTCCTTTACTGCTGAGAAGGTTTCCGAATGTTCAGTTTGCATAT
ACTGTATAGTTTGTTTTTGCGGCCTTTCAAACATACATAGGTATTGTAAATGATATATCGTTCTTTTAAA
ATAGTCGACTAATGCAAAAATAAATTCTTCATCACTTATTAGATCTACTTTTAATTTTTCTTCTAATGAA
TTGATAAAGTCTTTAACTAACTCATAAATCGATAAATTTCCTTCCTTAAAATATTGAACACTCTCCTCTT
TCTCTTTATTTATATCTTTGTAAACATATTTAGAACTCTTAATACTAATTGTTAACAAAATCTTATCTTG
TACTGTTAAGCTAACACCAAATTCACGTTCTAGCTTTTCGAATATTCTTCCTATTTTCACATAATCGGGA
GTTTCTGTATTAAAGTATAAAAACTTTCTATTTAATTGAACTTTGTATCCCTGTTGCTTTCGTTTTAATA
AAATTGCTATAAAAAAAGATAAATGCCTTTTAGAAACCACATGTAATGAGATTCCTAATGATTCTTCAAG
AGTTCCAAGGTATTGAAAAATAACTTCTTTTTTCAATTTTTCAAATGGCCACTCTGTATCATTATAAGAT
TTTAAATACAGATCCAAATACATTATCATGATTCGAACTTCATCCCCCTCAAGTCTAAGAGGTTTCTTAC
GAAGCTTCAAACCAAATTTTTTAAGATAATTCTCTACTCTTTTTAATGCAGGTAGAATAGATGGGACTTG
TATATATAATCTCTCTGCTAAGGTAGCAATTGTTTTTGTTTCTCTCTCAAATAAATGTTGTAATATCCGG
AAAGTTAAAGATTCCCGAAAAAGTAAGAAAGTAATTTCATTTCTATGTTTATTATAGGGTAGATAAATTC
TAACTCCCTTTCCCTTTTTTATTTTTATATGCCAGTCTTCAGGTAAAAAATCTTTGATAAATGAAATATC
TTTCATAATCGTTTTGTTACAACATCTTAAAATTTTAGAAATTTCAATAGTTGTAAACCATTTTTCTTCG
CTTGTAATTATTTCTAAGATTTGGATTTGTCTTTTTATATCTTTTTCCA
Protein Sequence 
>gi|229599687|ref|YP_002860667.1| capsule synthesis trans-acting positive regulator AcpB [Bacillus anthracis str. A0248] MEKDIKRQIQILEIITSEEKWFTTIEISKILRCCNKTIMKDISFIKDFLPEDWHIKIKKGKGVRIYLPYNKHRNEITFLLFRESLTFRILQHLFERETKTIATLAERLYIQVPSILPALKRVENYLKKFGLKLRKKPLRLEGDEVRIMIMYLDLYLKSYNDTEWPFEKLKKEVIFQYLGTLEESLGISLHVVSKRHLSFFIAILLKRKQQGYKVQLNRKFLYFNTETPDYVKIGRIFEKLEREFGVSLTVQDKILLTISIKSSKYVYKDINKEKEESVQYFKEGNLSIYELVKDFINSLEEKLKVDLISDEEFIFALVDYFKRTIYHLQYLCMFERPQKQTIQYMQTEHSETFSAVKEVYTEFVKKNEIADYVSVEEIAKVTMYIEASRLRYTSNYKKVLLVTGESESWAEYLAATLAKRFGDKIQISTVFFAKKSDHDVNADFIISTIPLDLGSTPIICINSIPTERDYTNIQYYLDLQDG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: acpB mutant is attenuated in mice (Drysdale et al., 2005).
COG COG3711K, under K: Transcription
References
Drysdale et al., 2005: Drysdale M, Heninger S, Hutt J, Chen Y, Lyons CR, Koehler TM. Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax. The EMBO journal. 2005; 24(1); 221-227. [PubMed: 15616593].