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atxA from Bacillus anthracis str. A0248

Victor ID 3645
Gene Name atxA from Bacillus anthracis str. A0248
Sequence Strain (Species/Organism) Bacillus anthracis str. A0248
NCBI Gene ID 7847839
NCBI Protein GI 229599851
Locus Tag BAA_A0151
Protein Accession YP_002860817.1
Other Database IDs UniProtKB-ID: C3PE22_BACAA
UniRef100: UniRef100_Q44636
UniRef90: UniRef90_Q44636
UniRef50: UniRef50_Q44636
UniParc: UPI0000001330
EMBL: CP001599
EMBL-CDS: ACQ51106.1
RefSeq_NT: NC_012656.1
EnsemblGenome: EBBACG00000127200.
EnsemblGenome_TRS: EBBACT00000127765
EnsemblGenome_PRO: EBBACP00000123378
GenomeReviews: CP001599_GR
KEGG: bai:BAA_A0151
ProtClustDB: CLSK862250
Taxonomy ID 592021
Plasmid No pXO1
Gene Starting Position 128028
Gene Ending Position 129455
Gene Strand (Orientation) -
Protein Name anthrax toxin expression trans-acting positive regulator
DNA Sequence 
>gi|229599713:128028-129455 Bacillus anthracis str. A0248 plasmid pXO1, complete sequence
TTTATATTATCTTTTTGATTTCATGAAAATCTCTTTCTGTAGGAAATTCCGAAATTTGTACAATAGGTAT
ATTTTTTATAGGTAAGTTAACATTAGAAATAATAATATCTATCTCCATGTCTTGGAGTGATTCGTTAGTT
AAATTTATAATAGTGTTTCTTACAATTTTAATAAGTCCATTATAACGTTTTTCAAGCAGTGCAGATATAT
ACTCTCGATGTATACATCCTTGTGAGGTGTATACATATATTTTTTTCGGGTTATTTTTAAATAGCATACG
TTGAGTTTCAAAATGCATTGTTAATAATGAAATTTCATAGCAGTCGAAATGGGAGTATACTGTATAGTTT
AAATTACTAATGCATTCTTGAATTGTATTAAATGTATTTGGATGACGCTGTTTTATATGCCTTATAAATT
TTATATTATAATTATAATATTGAATAAAGTTTTTATCTAATGCTTTTTTTATGATTAGAACAACATATGT
TAAAAAAGATTCATCATAATTTATCCCAAGTTGTAATTTATGTTCAATTCCTTTGGTAATTTCTTTAGCC
AAAGGCATAATTGTTTTTTTGTAGGAAGTTAATGTTTTATTGCTGTCTGTGGTAATAGAATTTCCAAGAG
ATAAAAGTAGTGCAAGGGCTAAAAATGAAATCTCAGTTTCATGTAATGTAACGCCGAAAGAGTTTTGTAG
CTCTGAGGTTATAGACGCTACTGTTTTATAATGATCATCATTTTTATTTACTAAAATAAGTCCACTTACA
TTATCTATTGTATTTCCTGATAGTAATCTGGAGATTGTTATAGCGAACAACACACACAATTTGTGTTTTG
AATAGGTGTACATTTGTACATTTAAAATTTTTTCCATTTTATTAATTAAATCAGTGATATTTTGTTTATT
AATATAGGGAAACGGCCAATAATCATTTGGAATATTGCAATATAACCTTAACATAAATACGCGGACATCT
TGTTCTCTTCCCGATATTTCTAGAGGTTTTTTTTTGATATTTAAATGACTGGATTGTATATCATAATTTA
TTTGATTAATAATTGGGTATAAAGCTCCTACTTGTAAGTGGAGTTTTTGAGCTAAGGATTGCATACTGTT
TTTTTTGAATACAAGTTCTTCGCAAATTTGAAGATTTAGTGATTTTCTTAAAATTTTTGATTCAACAAAG
GAAAGGGATTCATTTAATGGTTTTTTTAGATAAATTCCTTTTCCTTTTTGAACAAGTAAATTCCAAGATG
GAGGAATTTCGTCTTCTAATAATTTTAAATATTTTCGGACTGTTTTATCTGCGACCTGTAGATAATCAGA
TAATTCTTTAATTGTAAACCATCTATTTTGTTCATTGATAAAGTGTAGTAAATTAATTAATCTTATATGT
TCCTTTTCGATGGATATCGGTGTTAGCA
Protein Sequence 
>gi|229599851|ref|YP_002860817.1| anthrax toxin expression trans-acting positive regulator [Bacillus anthracis str. A0248] MLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFKKNSMQSLAQKLHLQVGALYPIINQINYDIQSSHLNIKKKPLEISGREQDVRVFMLRLYCNIPNDYWPFPYINKQNITDLINKMEKILNVQMYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYKTVASITSELQNSFGVTLHETEISFLALALLLSLGNSITTDSNKTLTSYKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIKKALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYSHFDCYEISLLTMHFETQRMLFKNNPKKIYVYTSQGCIHREYISALLEKRYNGLIKIVRNTIINLTNESLQDMEIDIIISNVNLPIKNIPIVQISEFPTERDFHEIKKII
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: atxA mutant is avirulent in mice (Koehler, 2002).
COG COG3711K, under K: Transcription
References
Koehler, 2002: Koehler TM. Bacillus anthracis genetics and virulence gene regulation. Current topics in microbiology and immunology. 2002; 271; 143-164. [PubMed: 12224521].