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cya from Bacillus anthracis str. A0248

Victor ID 3643
Gene Name cya from Bacillus anthracis str. A0248
Sequence Strain (Species/Organism) Bacillus anthracis str. A0248
NCBI Gene ID 7847735
NCBI Protein GI 229599815
Locus Tag BAA_A0144
Protein Accession YP_002860815.1
Other Database IDs UniProtKB-ID: C3PE20_BACAA
UniRef100: UniRef100_P40136
UniRef90: UniRef90_P40136
UniRef50: UniRef50_P40136
UniParc: UPI000000132F
EMBL: CP001599
EMBL-CDS: ACQ51070.1
RefSeq_NT: NC_012656.1
EnsemblGenome: EBBACG00000129663.
EnsemblGenome_TRS: EBBACT00000126820
EnsemblGenome_PRO: EBBACP00000123180
GenomeReviews: CP001599_GR
KEGG: bai:BAA_A0144
ProtClustDB: CLSK687645
Taxonomy ID 592021
Plasmid No pXO1
Gene Starting Position 122871
Gene Ending Position 125273
Gene Strand (Orientation) +
Protein Name calmodulin-sensitive adenylate cyclase
DNA Sequence 
>gi|229599713:122871-125273 Bacillus anthracis str. A0248 plasmid pXO1, complete sequence
AATGACTAGAAATAAATTTATACCTAATAAGTTTAGTATTATATCCTTTTCAGTATTACTATTTGCTATA
TCCTCCTCACAGGCTATAGAAGTAAATGCTATGAATGAACATTACACTGAGAGTGATATTAAAAGAAACC
ATAAAACTGAAAAAAATAAAACTGAAAAAGAAAAATTTAAAGACAGTATTAATAACTTAGTTAAAACAGA
ATTTACCAATGAAACTTTAGATAAAATACAGCAGACACAAGACTTATTAAAAAAGATACCTAAGGATGTA
CTTGAAATTTATAGTGAATTAGGAGGAGAAATCTATTTTACAGATATAGATTTAGTAGAACATAAGGAGT
TACAAGATTTAAGTGAAGAAGAGAAAAATAGTATGAATAGTAGAGGTGAAAAAGTTCCGTTTGCATCCCG
TTTTGTATTTGAAAAGAAAAGGGAAACACCTAAATTAATTATAAATATCAAAGATTATGCAATTAATAGT
GAACAAAGTAAAGAAGTATATTATGAAATTGGAAAGGGGATTTCTCTTGATATTATAAGTAAGGATAAAT
CTCTAGATCCAGAGTTTTTAAATTTAATTAAGAGTTTAAGCGATGATAGTGATAGTAGCGACCTTTTATT
TAGTCAAAAATTTAAAGAGAAGCTAGAATTGAATAATAAAAGTATAGATATAAATTTTATAAAAGAAAAT
TTAACTGAATTTCAGCATGCGTTTTCTTTAGCGTTTTCTTATTATTTTGCACCTGACCATAGAACGGTAT
TAGAGTTATATGCCCCCGACATGTTTGAGTATATGAATAAGTTAGAAAAAGGGGGATTTGAGAAAATAAG
TGAAAGTTTGAAGAAAGAAGGTGTGGAAAAAGATAGGATTGATGTGCTGAAAGGAGAAAAAGCACTTAAA
GCTTCAGGTTTAGTACCAGAACATGCAGATGCTTTTAAAAAAATTGCTAGAGAATTAAATACATATATTC
TTTTTAGGCCTGTTAATAAGTTAGCTACAAACCTTATTAAAAGTGGTGTGGCTACAAAGGGATTGAATGT
TCATGGAAAGAGTTCGGATTGGGGCCCTGTAGCTGGATACATACCATTTGATCAAGATTTATCTAAGAAG
CATGGTCAACAATTAGCTGTCGAGAAAGGAAATTTAGAAAATAAAAAATCAATTACAGAGCATGAAGGTG
AAATAGGTAAAATACCATTAAAGTTAGACCATTTAAGAATAGAAGAGTTAAAGGAAAATGGGATAATTTT
GAAGGGTAAAAAAGAAATTGATAATGGTAAAAAATATTATTTGTTAGAATCGAATAATCAGGTATATGAA
TTTAGAATTAGCGATGAAAACAACGAAGTACAATACAAGACAAAAGAAGGTAAAATTACTGTTTTAGGGG
AAAAATTCAATTGGAGAAATATAGAAGTGATGGCTAAAAATGTAGAAGGGGTCTTGAAGCCGTTAACAGC
TGACTATGATTTATTTGCACTTGCCCCAAGTTTAACAGAAATAAAAAAACAAATACCACAAAAAGAATGG
GATAAAGTAGTTAACACCCCAAATTCATTAGAAAAGCAAAAAGGTGTTACTAATTTATTGATTAAATATG
GAATTGAGAGGAAACCGGATTCAACTAAGGGAACTTTATCAAATTGGCAAAAACAAATGCTTGATCGTTT
GAATGAAGCAGTCAAATATACAGGATATACAGGGGGGGATGTGGTTAACCATGGCACAGAGCAAGATAAT
GAAGAGTTTCCTGAAAAAGATAACGAAATTTTTATAATTAATCCAGAAGGTGAATTTATATTAACTAAAA
ATTGGGAGATGACAGGTAGATTTATAGAAAAAAACATTACGGGAAAAGATTATTTATATTATTTTAACCG
TTCTTATAATAAAATAGCTCCTGGTAATAAAGCTTATATTGAGTGGACTGATCCGATTACAAAAGCCAAA
ATAAATACCATCCCTACGTCAGCAGAGTTTATAAAAAACTTATCCAGTATCAGAAGATCTTCAAATGTAG
GAGTTTATAAAGATAGTGGCGACAAAGACGAATTTGCAAAAAAAGAAAGCGTGAAAAAAATTGCAGGATA
TTTGTCAGACTATTACAATTCAGCAAATCATATTTTTTCTCAGGAAAAAAAGCGTAAAATATCAATATTT
CGTGGAATCCAAGCCTATAATGAAATTGAAAATGTTCTAAAATCTAAACAAATAGCACCAGAATACAAAA
ATTATTTTCAATATTTAAAGGAAAGGATTACCAATCAAGTTCAATTGCTTCTAACACATCAAAAATCTAA
TATTGAATTTAAATTATTGTATAAACAATTAAACTTTACAGAAAATGAAACGGATAATTTTGAGGTCTTC
CAAAAAATTATTGATGAAAAATA
Protein Sequence 
>gi|229599815|ref|YP_002860815.1| calmodulin-sensitive adenylate cyclase [Bacillus anthracis str. A0248] MTRNKFIPNKFSIISFSVLLFAISSSQAIEVNAMNEHYTESDIKRNHKTEKNKTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKIPKDVLEIYSELGGEIYFTDIDLVEHKELQDLSEEEKNSMNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFEKISESLKKEGVEKDRIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLSKKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKINTIPTSAEFIKNLSSIRRSSNVGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKSNIEFKLLYKQLNFTENETDNFEVFQKIIDEK
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: cya encodes EF protein, which with PA induces edema (Pezard et al., 1991).
References
Pezard et al., 1991: Pezard C, Berche P, Mock M. Contribution of individual toxin components to virulence of Bacillus anthracis. Infection and immunity. 1991; 59(10); 3472-3477. [PubMed: 1910002].