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alo from Bacillus anthracis str. A0248

Victor ID 3640
Gene Name alo from Bacillus anthracis str. A0248
Sequence Strain (Species/Organism) Bacillus anthracis str. A0248
NCBI Gene ID 7851421
NCBI Protein GI 229604714
Locus Tag BAA_3389
Protein Accession YP_002867524.1
Other Database IDs UniProtKB-ID: C3P241_BACAA
UniRef100: UniRef100_C3P241
UniRef90: UniRef90_C3LCD8
UniRef50: UniRef50_Q0TUS0
UniParc: UPI00001915CC
EMBL: CP001598
EMBL-CDS: ACQ50759.1
RefSeq_NT: NC_012659.1
EnsemblGenome: EBBACG00000125279.
EnsemblGenome_TRS: EBBACT00000127054
EnsemblGenome_PRO: EBBACP00000122840
GenomeReviews: CP001598_GR
KEGG: bai:BAA_3389
ProtClustDB: CLSK877006
Taxonomy ID 592021
Gene Starting Position 3086325
Gene Ending Position 3087863
Gene Strand (Orientation) -
Protein Name anthrolysin O
DNA Sequence 
>gi|229599883:3086325-3087863 Bacillus anthracis str. A0248, complete genome
CCTAATGACTAATAGTAGCAGTTGGATATAATGTTGTTCCTCCAATTGAAACCTTTATTTCATTTGTTAA
TGGAACATTTTGTTCATTAATGATAGTTCTCCACCATTCCCATGCAAGACCTGTACATTCTCTTGCAACG
ATTTTTATATTTTTTGAATTTGGTGGAAGAGGGATAACTGTAGAGTAATGGGCTGTTTTGTCTTTGCCAC
TACCTTCCCATGTTTTATGTGTTAGTACTTCTTTCCCATTTTGATCAAATGTAAATTCATCCCAAGATAC
ATCAAATTGAGCAACGTAAGCACCGTAATGATCGAGTGTCATTTTAGCACTTGAATATTCTGTAGTTGTC
GTCTCGATATAATCTGTATTGTTATGAACAGCAGCAGTTGCATTATCTTTTAAGAACGTGCTTGTATATG
AAATTGGGTATGCTGGATTTTTAAAGCTTAATTCAGCATTATCTTTAATAATATTTCGGATTTCATTGAA
ATCTTTTGTAACAACCTTGTTATGCTCTTTCGCATCTCCGCCTAATACTACAGCAGTAAAGGTACTTTCT
TCAAAAATATCTTTGTACTGTCCACTCGTTTCGACGCTGTTATTCTTAAGTAGAGCTTTAAATGCAGCTT
GTACATCTTTACTCTTAGATGTTGTTTCTAATTTTACATAAACCGTTCTACCATAAGCTACATTTGAAAC
CATAACAGGTGGAGCCGAATTACTTACTCCTTTACGAGTTAACTCATCAAAAGTAACACTATTATCAAAG
AGATCAGATGGATTATTAGGTAGTTCAGCACTTACAGTATAAAATATTTGTTTATATGCCGCCACCATCA
CTTTCTTTTCTCCATTTGCAACTGCATTAAAGTCAATATTTAGACTGTTATCAAGATATTTAGCATTAAC
ATTAAGAGCACTTGCGATTTGTGATTTACTATAAACCATAGATTCTGTATACTGCATTCTTGCAGGTAAC
GTATGTGTTGTGGAATACTTTTCATTCCAAGTAGATACTAAATCATCTACTGCTCCAGCCACATTACCAT
ATGTCGGATTTTGGACAGTGATTGTATTTTCTTTTCTCATGCCAGGTAAGTCTATACTAATATTCAAAGG
CTTTCTCTTAGCTACTAATAAACTCGGTTGATTGTCTGCAAATGCTTTATTGGCAAGTTGTACAGCTCCT
GGATACGTACGATTCACTACAGAATCAATAATCAAAATATCGACTGGTGACGTTGTAAGTGATTTTTTCT
CGCGTTCCACTACTACAAATTTACCGTTTGAATTGATACTCTCTTTCGGAATAAAACTCTCTACTTTATC
ACCATTTACTGCTAAAATATCTCTACTATCATACTTTAGATTTGCTATACCAGTATTAATATCACTAGCA
TTTTTTATTGCACCAGTTGCATTACCGGCTTGTGTTTCTGCAAAAGAAATAGACGAATAATGAATGGTAC
ATAGACTAACTAATAAACATGCAAGGAACTTTCTTCTTTTAGTGTTTTTCTTAATATTCAGAAAAATCA
Protein Sequence 
>gi|229604714|ref|YP_002867524.1| anthrolysin O [Bacillus anthracis str. A0248] MIFLNIKKNTKRRKFLACLLVSLCTIHYSSISFAETQAGNATGAIKNASDINTGIANLKYDSRDILAVNGDKVESFIPKESINSNGKFVVVEREKKSLTTSPVDILIIDSVVNRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQNPTYGNVAGAVDDLVSTWNEKYSTTHTLPARMQYTESMVYSKSQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYKQIFYTVSAELPNNPSDLFDNSVTFDELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSGQYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSFKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTTEYSSAKMTLDHYGAYVAQFDVSWDEFTFDQNGKEVLTHKTWEGSGKDKTAHYSTVIPLPPNSKNIKIVARECTGLAWEWWRTIINEQNVPLTNEIKVSIGGTTLYPTATISH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: alo mutant had diminished ability to grow in association with macrophages (Heffernan et al., 2007).
References
Heffernan et al., 2007: Heffernan BJ, Thomason B, Herring-Palmer A, Hanna P. Bacillus anthracis anthrolysin O and three phospholipases C are functionally redundant in a murine model of inhalation anthrax. FEMS microbiology letters. 2007; 271(1); 98-9105. [PubMed: 17419764].