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clpX from Bacillus anthracis str. A0248

Victor ID 3639
Gene Name clpX from Bacillus anthracis str. A0248
Sequence Strain (Species/Organism) Bacillus anthracis str. A0248
NCBI Gene ID 7851138
NCBI Protein GI 229600744
Locus Tag BAA_4722
Protein Accession YP_002868756.1
Other Database IDs UniProtKB-ID: CLPX_BACAA
UniRef100: UniRef100_C3P9F7
UniRef90: UniRef90_C3P9F7
UniRef50: UniRef50_Q833M7
UniParc: UPI0000167644
EMBL: CP001598
EMBL-CDS: ACQ46789.1
RefSeq_NT: NC_012659.1
EnsemblGenome: EBBACG00000127322
EnsemblGenome_TRS: EBBACT00000129234
EnsemblGenome_PRO: EBBACP00000122202
GenomeReviews: CP001598_GR
KEGG: bai:BAA_4722
ProtClustDB: PRK05342
Taxonomy ID 592021
Gene Starting Position 4281143
Gene Ending Position 4282402
Gene Strand (Orientation) -
Protein Name ATP-dependent Clp protease, ATP-binding subunit ClpX
DNA Sequence 
>gi|229599883:4281143-4282402 Bacillus anthracis str. A0248, complete genome
ATTATGCAGATGTTTTTGTATCAAGTACAGTACCGTCTTGTAACACCAATTTTGGTGCTGCATTATCAGC
TACTGTTTCTTTTGTAAGAATACACTTCTCGATATCTTTGCGAGATGGTAGCTCGAACATTACCTCAAGC
ATTAAGCCTTCAATAATAGAACGAAGTCCACGAGCACCTGTTTTACGTTCAATTGCTTTTTTCGCAATTT
CAATTAGTGCACCTTCTTCAAACTCTAACTCAACATCGTCAAGCTCCAATAGTTTTTGGAATTGCTTAAC
AAGTGCATTTTTCGGTTTCGTTAAAATATCAACAAGAGCATCTTCATCAAGTGGCTCTAGGTTCGCAATA
ACTGGAAGACGACCGATAAACTCTGGAATTAAACCAAATCTTAAAAGGTCTTCTGGTAATACGTGAGATA
AAACATGCTTCTCATTTACATCAGCATTTTTCTTCTCAGAACCAAATCCAATTACCTTTTCACCAAGACG
GCGTTTAATAATTGGCTCGATGCCATCAAACGCTCCACCACAGATGAATAAGATATTCGTTGTATCAATT
TGAATAAACTCTTGGTGCGGATGCTTACGACCACCTTGAGGTGGAACGCTTGCTACAGTACCTTCTAAAA
TTTTCAGAAGTGCCTGCTGCACACCTTCACCAGATACATCACGTGTAATTGATGGATTTTCGGACTTACG
TGCCACTTTATCAATCTCATCAATATAAATGATTCCTTTTTCCGCTTTTTCTACATCATAATCCGCTGCT
TGGATTAATTTAAGTAAGATGTTTTCTACATCTTCCCCAACGTATCCAGCTTCAGTTAAAGATGTTGCGT
CCGCGATTGCAAATGGAACATTTAAAATACGCGCTAACGTTTGTGCCAGTAATGTTTTACCACTACCTGT
TGGCCCGATAAGTGCGATATTACTCTTCGCTAATTCTACATCATCAATTTTGCTGTTAGAATTAATGCGT
TTGTAATGGTTATATACCGCTACCGCTAGTGCTTTTTTCGCGTTATCTTGTCCGATGACATACTCATCTA
AAATTTCACGAATTTCTACCGGTTTCGGTACATCTTTGAATTCTACTTCTTCGTCTTTCGCAAGCTCCTC
TTGTACAATTTCAGTACAAAGTTCGATACACTCGTCACAAATGTAAACACCTGGACCTGCAACTAACTTT
CGGACTTGTGTTTGTGTTTTACCACAGAAAGAACATTTTAATTGCCCTTTTTCATCATTAAATTTAAACA
Protein Sequence 
>gi|229600744|ref|YP_002868756.1| ATP-dependent protease ATP-binding subunit ClpX [Bacillus anthracis str. A0248] MFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: clpX deletion mutant is attenuated in mice (McGillivray et al., 2009).
COG COG1219O, under O: Posttranslational modification, protein turnover, chaperones
References
McGillivray et al., 2009: McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. Journal of innate immunity. 2009; 1(5); 494-506. [PubMed: 20375606].