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luxS from Streptococcus pneumoniae ATCC 700669

Victor ID 3628
Gene Name luxS from Streptococcus pneumoniae ATCC 700669
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7329460
NCBI Protein GI 221231219
Locus Tag SPN23F_03130
Protein Accession YP_002510371.1
Other Database IDs UniProtKB-ID: LUXS_STRPJ
UniRef100: UniRef100_B8ZL57
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI000172AFBC
EMBL: FM211187
EMBL-CDS: CAR68170.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000071526
EnsemblGenome_TRS: EBSTRT00000072743
EnsemblGenome_PRO: EBSTRP00000067146
GenomeReviews: FM211187_GR
HOGENOM: HBG347473
OMA: VRIAKTM
ProtClustDB: PRK02260
Taxonomy ID 561276
Gene Starting Position 298668
Gene Ending Position 299150
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase
DNA Sequence 
>gi|221230948:298668-299150 Streptococcus pneumoniae ATCC 700669, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTCTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGACAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|221231219|ref|YP_002510371.1| S-ribosylhomocysteinase [Streptococcus pneumoniae ATCC 700669] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWARLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].