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cbpE from Streptococcus pneumoniae ATCC 700669

Victor ID 3624
Gene Name cbpE from Streptococcus pneumoniae ATCC 700669
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7328890
NCBI Protein GI 221231701
Locus Tag SPN23F_08530
Protein Accession YP_002510853.1
Other Database IDs UniProtKB-ID: B8ZP33_STRPJ
UniRef100: UniRef100_B8ZP33
UniRef90: UniRef90_B8ZP33
UniRef50: UniRef50_D3H8I6
UniParc: UPI000152B846
EMBL: FM211187
EMBL-CDS: CAR68684.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000071113.
EnsemblGenome_TRS: EBSTRT00000071451
EnsemblGenome_PRO: EBSTRP00000067826
GenomeReviews: FM211187_GR
HOGENOM: HBG702245
ProtClustDB: CLSK559958
Taxonomy ID 561276
Gene Starting Position 834685
Gene Ending Position 836568
Gene Strand (Orientation) +
Protein Name choline binding protein E
DNA Sequence 
>gi|221230948:834685-836568 Streptococcus pneumoniae ATCC 700669, complete genome
AATGAAAAAGAAATTAACTAGTTTAGCACTTGTAGGCGCTTTTTTAGGTTTGTCATGGTATGGGAATGTT
CAGGCTCAAGAAAGTTCAGGAAATAAAATCCACTTTATCAATGTTCAAGAAGGTGGCAGTGATGCGATTA
TTCTTGAAAGCAATGGACATTTTGCCATGGTGGATACAGGAGAAGATTATGATTTCCCAGATGGAAGTGA
TTCTCGCTATCCATGGAGAGAAGGAATTGAAACGTCTTATAAGCATGTTCTAACAGACCGTGTCTTTCGT
CGTTTGAAGGAATTGGGTGTCCAAAAACTTGATTTTATTTTGGTGACCCATACCCACAGTGATCATATTG
GAAATGTTGATGAATTACTGTCTACCTATCCAGTTGACCGAGTCTATCTTAAGAAATATAGTGATAGTCG
TATTACTAATTCTGAACGTCTATGGGATAATCTGTATGGCTATGATAAGGTTTTACAGACTGCTGCAGAA
AAAGGTGTTTCAGTTATTCAAAATATCACACAAGGGGATGCTCATTTTCAGTTTGGGGACATGGATATTC
AGCTCTATAATTATGAAAATGAAACTGATTCATCGGGTGAATTAAAGAAAATTTGGGATGACAATTCCAA
TTCCTTGATTAGCGTGGTGAAAGTCAATGGCAAGAAAATTTACCTTGGGGGCGATTTAGATAATGTTCAT
GGAGCAGAAGACAAGTATGGTCCTCTCATTGGAAAAGTTGATTTGATGAAGTTTAATCATCACCATGATA
CCAACAAATCAAATACCAAGGATTTCATTAAAAATTTGAGTCCGAGTTTGATTGTTCAAACTTCGGATAG
TCTACCTTGGAAAAATGGTGTTGATAGTGAGTATGTTAATTGGCTCAAAGAACGAGGAATTGAGAGAATC
AATGCAGCCAGCAAAGACTATGATGCAACAGTTTTTGATATTCGACAAGACGGTTTAGTAAACATTTCAA
CTTCCTACAAGCCGATTCCAAGTTTTCAAGCTGGTTGGCATAAGAGTTCATATGGAAACTGGTGGTATCA
AGCGCCTGATTCTACAGGAGAATATGCTGTCGGTTGGAATGAAATTAAGGGTGAATGGTATTACTTTAAC
CAAACGGGTATCTTATTACAGAATCAATGGAAAAAATGGAACAATCGTTGGTTCTATTTGACAGACTCTG
GTGTTGCTGCTAAAAATTGGAAGAAAATCGCTGGAATCTGGTATTATTTTAACAAAGAAAACCAGATGGA
AATTGGTTGGATTCAAGATAAAGAGCAGTGGTATTATTTGGATGTTGATGGCTCTATGAAGACAGGTTGG
CTTCAATATAAGGGGCAATGGTATTACTTTGCTCCATCAGGGGAAATGAAAACGGGCTGGGTAAAAGATA
AAGAAGCCTGGTACTATATGGATTCTACTGGTATCATGAAGACAGGTGAGATAGAAGTTGCTGGACATCA
TTACTATCTAGAAGAATCAGGAGCTATGAAGCAAGGCTGGCTTAAAAAGGCAAATGATTGGTATTTCTAC
AAGACAGATGGTTCACGAGCTATAGGTTGGATTAAAGACAAGGATAAATGGTACTTCTTGAAAGAAAATG
GTCAATTACTTGTGAATGGTAAGACACCAGAAGGCTATACTGTGGATTCAAGTGGTGCCTGGTTAGTGGA
TGTTCCGATCGAGAAATCTGCTACAATTAAAACTACAAGTCATTCAGAAATAAAAGAATCCAAAGAAGTA
GTGAAAAAGGATCTTGAAAATAAAGAAACGAGTCAACATGAAAGTGTTACAAATTCTTCAACTAGTCAAG
ATTTGACATCCTCAACTTCACAAAGCTCTGAAACGAGTGTAAACAAATCGGAATCAGAACAGTA
Protein Sequence 
>gi|221231701|ref|YP_002510853.1| choline binding protein E [Streptococcus pneumoniae ATCC 700669] MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSDAIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQKLDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQTAAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKVNGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKANDWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESEQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpE has reduced colonization of nasopharynx of rats and reduced adherence to human epithelial cells (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].