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pclA

Victor ID 3622
Gene Name pclA
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7328731
NCBI Protein GI 221232257
Locus Tag SPN23F_15100
Protein Accession YP_002511410.1
Other Database IDs UniProtKB-ID: B8ZLE6_STRPJ
UniRef100: UniRef100_B2DYU4
UniRef90: UniRef90_E0SVM6
UniRef50: UniRef50_E0SVM6
UniParc: UPI000152F4E2
EMBL: FM211187
EMBL-CDS: CAR69291.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000071770.
EnsemblGenome_TRS: EBSTRT00000071029
EnsemblGenome_PRO: EBSTRP00000066506
GenomeReviews: FM211187_GR
HOGENOM: HBG697130
ProtClustDB: CLSK884115
Taxonomy ID 561276
Gene Starting Position 1461838
Gene Ending Position 1462386
Gene Strand (Orientation) +
Protein Name putative NADPH-dependent FMN reductase
DNA Sequence 
>gi|221230948:1461838-1462386 Streptococcus pneumoniae ATCC 700669, complete genome
CATGTCTAAAAAAGTATTATTTATCGTCGGATCACTACGTCAAGGTTCTTTCAACCACCAAATGGCGCTC
GAAGCTGAGAAAGCACTTGCTGGTAAAGCGGAAGTTAGCTACCTTGATTATTCAGCCCTTCCTCTCTTCA
GCCAAGATTTGGAAGTTCCAACACATCCAGCTGTAGCTGCTGCTCGTGAAGCAGTTCTCGTTGCGGATGC
TATCTGGATTTTCTCTCCAGTCTACAACTTCTCTATCCCTGGTACAGTGAAAAACTTGCTTGACTGGCTA
TCTCGTGCCCTTGACTTGTCTGATACACGTGGCGTTTCTGCCCTTCAAGACAAGTTTGTCACAGTATCAT
CTGTAGCCAATGCAGGGCACGATCAACTTTTCGCTATCTACAAAGACCTCTTGCCATTTATCCGTACACA
AGGCGTTGGTGATTTCACTGCTGCACGTGTTAATGACTCTGCCTGGGCAGACGGAAAATTGGTTCTTGAA
GAAACAGTCCTAAACTCACTTGAAAAACAAGCTCAAGACTTGGTCGAAGCGATTCAGTA
Protein Sequence 
>gi|221232257|ref|YP_002511410.1| NADPH-dependent FMN reductase [Streptococcus pneumoniae ATCC 700669] MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALPLFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDTRGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKLVLEETVLNSLEKQAQDLVEAIQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pclA mutant was defective in adherence and invasion of host cells in vitro (Paterson et al., 2008).
COG COG0431R, under R: General function prediction only
References
Paterson et al., 2008: Paterson GK, Nieminen L, Jefferies JM, Mitchell TJ. PclA, a pneumococcal collagen-like protein with selected strain distribution, contributes to adherence and invasion of host cells. FEMS microbiology letters. 2008; 285(2); 170-176. [PubMed: 18557785].