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ciaR from Streptococcus pneumoniae ATCC 700669

Victor ID 3613
Gene Name ciaR from Streptococcus pneumoniae ATCC 700669
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7327765
NCBI Protein GI 221231598
Locus Tag SPN23F_07270
Protein Accession YP_002510750.1
Other Database IDs UniProtKB-ID: B8ZNF8_STRPJ
UniRef100: UniRef100_B8ZNF8
UniRef90: UniRef90_P0A4H8
UniRef50: UniRef50_P0A4H8
UniParc: UPI00019235DD
EMBL: FM211187
EMBL-CDS: CAR68571.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000072196.
EnsemblGenome_TRS: EBSTRT00000071870
EnsemblGenome_PRO: EBSTRP00000067860
GenomeReviews: FM211187_GR
HOGENOM: HBG753323
ProtClustDB: CLSK876907
Taxonomy ID 561276
Gene Starting Position 709853
Gene Ending Position 710527
Gene Strand (Orientation) +
Protein Name response regulator protein
DNA Sequence 
>gi|221230948:709853-710527 Streptococcus pneumoniae ATCC 700669, complete genome
CATGATAAAAATCTTATTGATTGAGGATGACCTAGGTCTGTCAAATTCAGTATTTGACTTTTTAGACGAT
TTTGCGGATGTTATGCAGGTATTTGATGGAGAAGAAGGTCTCTACGAAGCTGAGAGTGGTGTCTATGACT
TGATTTTGCTGGATTTGATGTTGCCAGAAAAAAATGGTTTCCAAGTCTTAAAAGAATTGCGTGAAAAGGG
AATTACGACACCAGTTCTGATTATGACTGCCAAGGAAAGTTTGGATGACAAGGGACATGGATTTGAACTG
GGAGCGGATGATTATCTGACCAAACCTTTCTACCTAGAAGAACTTAAAATGCGAATTCAGGCCCTTCTCA
AACGTTCAGGGAAGTTTAATGAAAACACCTTGACTTATGGGAATATCGTGGTTAATTTATCAACCAATAC
CGTTAAAGTTGAAGATACTCCTGTCGAATTGCTGGGGAAAGAGTTCGATTTACTAGTTTATTTCCTTCAA
AATCAAAATGTGATTTTGCCTAAGACGCAGATTTTTGACCGTCTATGGGGATTTGATAGTGATACAACGA
TTTCGGTTGTCGAAGTCTATGTTTCAAAAGTCCGTAAGAAATTAAAGGGAACCACTTTTGCAGAGAATTT
GCAAACCTTGCGTAGTGTTGGGTATCTTTTAAAAGATGTTCAGTA
Protein Sequence 
>gi|221231598|ref|YP_002510750.1| response regulator protein [Streptococcus pneumoniae ATCC 700669] MIKILLIEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVYFLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYLLKDVQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ciaR mutant is attenuated in mice (Ibrahim et al., 2004).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Ibrahim et al., 2004: Ibrahim YM, Kerr AR, McCluskey J, Mitchell TJ. Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae. Journal of bacteriology. 2004; 186(16); 5258-5266. [PubMed: 15292127].