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nanA from Streptococcus pneumoniae ATCC 700669

Victor ID 3612
Gene Name nanA from Streptococcus pneumoniae ATCC 700669
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7327738
NCBI Protein GI 221232004
Locus Tag SPN23F_12210
Protein Accession YP_002511156.1
Other Database IDs UniProtKB-ID: B8ZK43_STRPJ
UniRef100: UniRef100_B2IP31
UniRef90: UniRef90_E0SUD2
UniRef50: UniRef50_A3CK37
UniParc: UPI000172BB63
EMBL: FM211187
EMBL-CDS: CAR69024.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000072014.
EnsemblGenome_TRS: EBSTRT00000071199
EnsemblGenome_PRO: EBSTRP00000067408
GenomeReviews: FM211187_GR
HOGENOM: HBG358848
ProtClustDB: CLSK877014
Taxonomy ID 561276
Gene Starting Position 1189319
Gene Ending Position 1190236
Gene Strand (Orientation) -
Protein Name probable N-acetylneuraminate lyase
DNA Sequence 
>gi|221230948:1189319-1190236 Streptococcus pneumoniae ATCC 700669, complete genome
ATTATAAAAATTCTTTTCGTGCTTGTTGAATAAGTTCTGCTGCTTGTTTTGCAACTTCCAAGTCACCTTC
TGCCAATGCTTCTAAGGGTTGACGAACAGAACCTAAATCAAGTTTTTCATTTAGACGCAAAACCTCTTTT
GCTACAGCATACATATTTGCCTTACCTGATATCATCTTATAGATAACTTCATTGATAGCATATTGAAGTT
TTTTAGCAGTATCTAAATCTCGTTCTTGAATCAAACTTTCCAATTTCAAGAACAAATCTGGCATAACGCC
ATAAGTACCACCAATACCAGCTTCTGCTCCCATCAAGCGACCACCAAGATATTGTTCATCTGGACCATTG
AATACAATGTAATCTTCTCCACCTGCAGCTACAAACATTTGAATATCTTGTACAGGCATAGAAGAATTTT
TAACTCCAATCACACGAGGATTTTGACGCATTGTTGCATACAAACTACCAGTCAACGCAACCCCTGCCAA
TTGTGGAATATTATAAATGATAAAATCTGTATTTGGCGCAGCTTCACTCATTGCATTCCAATATGCTGCA
ATTGAATATTCTGGCAATTTGAAGTAAATAGGTGGGATAGCAGCAATAGCATCGACTCCAACACTTTCTG
AATGTTTTGCCAATTCAATACTATCTTTCGTGTTATTACATGCAACATGGTTGATAACTGTTAATTTACC
TTTAGCAACTTCCATAACAGCTTCAATAATTTGTTTACGATCTTCTACACTTTGGTAAATACATTCACCT
GAAGAACCATTTACATAGATACCTTTTACACCTTTGTCAATGAAATATTGCACCAGAGATTTTACACGTT
CTTGGCTAATTTCACCATTTTCATCATAGCAAGCATAAAATGCAGGAATAACGCCTTTGTATTTAGTTAA
ATCTTTCA
Protein Sequence 
>gi|221232004|ref|YP_002511156.1| N-acetylneuraminate lyase [Streptococcus pneumoniae ATCC 700669] MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGIYVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGVDAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQNPRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPDLFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVRQPLEALAEGDLEVAKQAAELIQQARKEFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nanA mutant is attenuated in mice (Polissi et al., 1998).
COG COG0329EM, under E: Amino acid transport and metabolism; M: Cell wall/membrane/envelope biogenesis
References
Polissi et al., 1998: Polissi A, Pontiggia A, Feger G, Altieri M, Mottl H, Ferrari L, Simon D. Large-scale identification of virulence genes from Streptococcus pneumoniae. Infection and immunity. 1998; 66(12); 5620-5629. [PubMed: 9826334].