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lytB from Streptococcus pneumoniae ATCC 700669

Victor ID 3609
Gene Name lytB from Streptococcus pneumoniae ATCC 700669
Sequence Strain (Species/Organism) Streptococcus pneumoniae ATCC 700669
NCBI Gene ID 7327431
NCBI Protein GI 221231728
Locus Tag SPN23F_08900
Protein Accession YP_002510880.1
Other Database IDs UniProtKB-ID: B8ZP62_STRPJ
UniRef100: UniRef100_B2E180
UniRef90: UniRef90_P59205
UniRef50: UniRef50_P59205
UniParc: UPI000050D499
EMBL: FM211187
EMBL-CDS: CAR68716.1
RefSeq_NT: NC_011900.1
EnsemblGenome: EBSTRG00000071178.
EnsemblGenome_TRS: EBSTRT00000070801
EnsemblGenome_PRO: EBSTRP00000066495
GenomeReviews: FM211187_GR
HOGENOM: HBG702253
ProtClustDB: CLSK559969
Taxonomy ID 561276
Gene Starting Position 862889
Gene Ending Position 864865
Gene Strand (Orientation) +
Protein Name putative endo-beta-N-acetylglucosaminidase
DNA Sequence 
>gi|221230948:862889-864865 Streptococcus pneumoniae ATCC 700669, complete genome
AATGAAGAAAGTAAGATTTATTTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCT
AGTGATGGTACTTGGCAAGGAAAACAGTATCTGAAAGAAGATGGCAGTCAAGCAGCGAATGAGTGGGTTT
TTGATACTCATTATCAATCTTGGTTCTATATAAAAGCAGATGCTAACTATGCTGAAAATGAATGGCTAAA
GCAAGGTGACGACTATTTTTACCTCAAATCTGGTGGCTATATGGCCAAATCAGAATGGGTAGAAGACAAG
GGAGCCTTTTATTATCTTGACCAAGATGGAAAGATGAAACGAAATGCTTGGGTAGGAACTTCCTATGTTG
GTGCAACAGGTGCCAAAGTAATAGAAGACTGGGTCTATGATTCTCAATACGATGCTTGGTTTTATATCAA
AGCAGATGGACAGCACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTATTATTTCAAATCCGGT
GGTTATCTACTGACAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTACAGCAAG
GTTGGCTTTTTGACAAACAATACCAATCTTGGTTTTACATAAAAGAAAATGGAAACTATGCTGATAAAGA
ATGGATTTTCGAGAATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATT
TGGGATAAGGAATCTTGGTTTTACCTCAAGTTTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATT
CTCATAGTCAAGCCTGGTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAA
GGAATCTTGGTTTTATCTCAAATCTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGT
CAAGCTTGGTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTT
GGTTTTACCTCAAGTCTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCCTG
GTACTACTTCAAATCTGGTGGCTACATGGCGAAAAATGAGACAGTAGATGGTTATCAGCTTGGAAGCGAT
GGTAAATGGCTTGGAGGAAAAGCTACAAATAAAAATGCTGCTTACTATCAAGTAGTGCCTGTCACAGCCA
ATGTTTATGATTCAGATGGTGAAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAGATAAGGA
TAGAAAAAGTGATGACAAGCGCTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGAT
TTACAAGCGCTAGATGCTAGTAAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACT
ATGTGGCTCAGAATGCTAGTATCCCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTA
TTCGGCAGATGGCCTGCATTTTGATGGTTTTAAGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAG
GCTACAAACTACAGTGCTGAAGAATTGGATAAGGTATTTAGTTTGCTAAACATTAATAATAGCCTTTTGG
AGAACAAGGGCGCTACTTTTAAGGAAGCCGAAGAACATTATCATATCAATGCCCTTTATCTCCTTGCCCA
TAGTGCCCTAGAAAGTAACTGGGGAAGAAGTAAAATTGCCAAAGATAAGAATAATTTCTTTGGCATTACA
GCCTATGATACGACCCCTTACCTTTCTGCCAAGACATTTGATGATGTGGATAAGGGAATTTTAGGTGCAA
CCAAGTGGATTAAGGAAAATTATATCGATAGGGGAAGAACTTTCCTTGGAAACAAGGCTTCTGGTATGAA
TGTGGAATATGCTTCAGACCCTTATTGGGGCGAAAAAATTGCTAGTGTGATGATGAAAATCAATGAGAAG
CTAGGTGGCAAAGATTA
Protein Sequence 
>gi|221231728|ref|YP_002510880.1| endo-beta-N-acetylglucosaminidase [Streptococcus pneumoniae ATCC 700669] MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytB has reduced colonization of nasopharynx of rats compared to the wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].