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clpP from Listeria monocytogenes HCC23

Victor ID 3603
Gene Name clpP from Listeria monocytogenes HCC23
Sequence Strain (Species/Organism) Listeria monocytogenes HCC23
NCBI Gene ID 7079328
NCBI Protein GI 217963429
Locus Tag LMHCC_0131
Protein Accession YP_002349107.1
Other Database IDs UniProtKB-ID: B8DBP2_LISMH
UniRef100: UniRef100_B8DBP2
UniRef90: UniRef90_Q71WV9
UniRef50: UniRef50_Q8YQX8
UniParc: UPI0001697455
EMBL: CP001175
EMBL-CDS: ACK38493.1
RefSeq_NT: NC_011660.1
GenomeReviews: CP001175_GR
KEGG: lmh:LMHCC_0131
HOGENOM: HBG558421
OMA: SPMEAQD
ProtClustDB: PRK00277
Taxonomy ID 552536
Gene Starting Position 127095
Gene Ending Position 127691
Gene Strand (Orientation) -
Protein Name ATP-dependent Clp protease proteolytic subunit
DNA Sequence 
>gi|217963303:127095-127691 Listeria monocytogenes HCC23, complete genome
ATTAGCCTTTTAAGCCAGATTTATTAATGATGATATCATCAATTAAGCCATAATCTTTTGCTTCTTGTGC
AGTCATGAAATTATCACGATCTGTATCACGAGCAATGACTTCATACGGTTGGCCTGTTTTTTCAGCCATA
ATTGTATTCATACGTTCTTTGATTTTTAAAATGTGACGAGCAGCGATTTCGATTTCAGTCGCTTGACCTT
GAGCACCGCCAAGTGGTTGGTGAATCATAATTTCTGCATTTGGTAAGGCAAAACGTTTACCACTTGCGCC
AGCTGTTAGTAGGAATGAGCCCATTGAAGCAGCCATACCCATGCCGATTGTTTGCACGTCCGCTTTAACG
AAATTCATTGTATCGTAAATGGCCATACCAGCTGAAATACTTCCGCCTGGTGAATTGATATATAAGAAAA
TATCTTTTTCAGGATCTTGTGCATCTAGGAATAATAATTGAGATACGATCGAATTTGCCACGTTATCATC
AATTGCAGATCCTAACATAATAATTCTGTCTTTTAATAAACGGGAATAAATGTCGTATGCACGTTCACCG
CGGCTAGTTTGTTCGATTACTGTTGGAATTAAGTTCA
Protein Sequence 
>gi|217963429|ref|YP_002349107.1| ATP-dependent Clp protease proteolytic subunit [Listeria monocytogenes HCC23] MNLIPTVIEQTSRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLDAQDPEKDIFLYINSPGGSISAGMAIYDTMNFVKADVQTIGMGMAASMGSFLLTAGASGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILKIKERMNTIMAEKTGQPYEVIARDTDRDNFMTAQEAKDYGLIDDIIINKSGLKG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Gaillot et al., 2000: Gaillot O, Pellegrini E, Bregenholt S, Nair S, Berche P. The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes. Molecular microbiology. 2000; 35(6); 1286-1294. [PubMed: 10760131].