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clpP from Listeria monocytogenes HCC23

Victor ID 3600
Gene Name clpP from Listeria monocytogenes HCC23
Sequence Strain (Species/Organism) Listeria monocytogenes HCC23
NCBI Gene ID 7078568
NCBI Protein GI 217964793
Locus Tag LMHCC_1513
Protein Accession YP_002350471.1
Other Database IDs UniProtKB-ID: B8DC94_LISMH
UniRef100: UniRef100_B8DC94
UniRef90: UniRef90_Q720U2
UniRef50: UniRef50_Q2K5Q0
UniParc: UPI0001697E25
EMBL: CP001175
EMBL-CDS: ACK39857.1
RefSeq_NT: NC_011660.1
GenomeReviews: CP001175_GR
KEGG: lmh:LMHCC_1513
HOGENOM: HBG558421
OMA: IHDMIKF
ProtClustDB: PRK12553
Taxonomy ID 552536
Gene Starting Position 1522763
Gene Ending Position 1523335
Gene Strand (Orientation) +
Protein Name ATP-dependent Clp protease proteolytic subunit
DNA Sequence 
>gi|217963303:1522763-1523335 Listeria monocytogenes HCC23, complete genome
CATGGCAGAGAATAAAAATAATGAAAATATCACAAATATCCTTACCCAAAAATTGATTGATACACGAACG
GTGTTAATTTACGGGGAAATCAATCAGGAGTTAGCCGAAGACGTTTCTAAGCAGCTTTTACTTTTGGAAT
CTATTAGCAATGATCCAATTACGATTTTTATTAATAGCCAAGGCGGACACGTTGAAGCAGGCGACACCAT
TCATGATATGATTAAATTCATTAAGCCTACAGTGAAAGTCGTTGGAACTGGCTGGGTTGCAAGCGCTGGT
ATTACAATTTACTTAGCTGCTGAAAAAGAAAATCGCTTTAGCCTTCCAAATACGCGCTACATGATTCACC
AACCTGCTGGCGGCGTTCAAGGTCAAAGTACCGAAATCGAAATCGAAGCAAAAGAAATTATCCGGATGCG
CGAAAGAATTAATCGCTTAATCGCCGAAGCAACCGGTCAATCATACGAGCAAATTTCTAAAGACACAGAT
CGTAACTTCTGGCTTTCAGTTAATGAAGCGAAAGATTATGGCATCGTAAGTGAAATCATTGAAAACCGCG
ATGGCTTAAAATA
Protein Sequence 
>gi|217964793|ref|YP_002350471.1| ATP-dependent Clp protease proteolytic subunit [Listeria monocytogenes HCC23] MAENKNNENITNILTQKLIDTRTVLIYGEINQELAEDVSKQLLLLESISNDPITIFINSQGGHVEAGDTIHDMIKFIKPTVKVVGTGWVASAGITIYLAAEKENRFSLPNTRYMIHQPAGGVQGQSTEIEIEAKEIIRMRERINRLIAEATGQSYEQISKDTDRNFWLSVNEAKDYGIVSEIIENRDGLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Gaillot et al., 2000: Gaillot O, Pellegrini E, Bregenholt S, Nair S, Berche P. The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes. Molecular microbiology. 2000; 35(6); 1286-1294. [PubMed: 10760131].