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ipgB from Shigella flexneri 5a

Victor ID 36
Gene Name ipgB from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876493
NCBI Protein GI 13449076
Locus Tag pWR501_p137
Protein Accession NP_085292.1
Other Database IDs UniProtKB-ID: IPGB_SHIFL
UniRef100: UniRef100_P33548
UniRef90: UniRef90_P33548
UniRef50: UniRef50_P33548
UniParc: UPI000012D7DE
EMBL: M86530
EMBL: AL391753
EMBL: AF348706
EMBL: X15319
EMBL: AF386526
EMBL: M34849
EMBL-CDS: AAD15223.1
EMBL-CDS: CAC05805.1
EMBL-CDS: AAK18448.1
EMBL-CDS: CAA33379.1
EMBL-CDS: AAL72342.1
EMBL-CDS: AAA98422.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093003
EnsemblGenome_TRS: EBESCT00000093959
EnsemblGenome_PRO: EBESCP00000090166
GenomeRev
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 106544
Gene Ending Position 107170
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|13448939:106544-107170 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TTTAATTTGTATTGCTTTGACGGTATACAGCCTTTAGAACCTCTGCGCTTATTTCTATTTGTAAAACTTT
TGTTGATTCATTAAATATTTTATCGTAGACGGAACTGGATACTAGATTTGTAAGATCCTTCATTTGTGTG
TTAAACAAATCCATGTCACTGCTATAGCGTTTTAAAATCTTTGCTCTGAGGCCAGATGAGGCAATCTCGT
TTAGTGCTGTATGACTGATAGATGTTTGTGCTGATTTTTCATCAAGTTTTATATCCGGGAATTTTTTTTC
AATAGCTGCAAATATGTTTTTTTTGTTATCTGAGGTCAAAACAACTCCATTGTGTATGGCCATTTCATCT
ATACTTCTGTTTATCATTGAAGAGACATAAGTGGTTCGCTCTTGGCTCATCCAACAAAATAGTTGATTCC
CCGAATTACTATCTTTTATTTTGTCTATGACGCTGTCCCTGATTTTATTTATATTCACCGGGCATCCAAA
ATTCTTCTGAGGAAAGCGTTGTTTTAAGTTAAAAACAGATAATATTTTCTTTACAAGCTTATTGCGACTT
AACGAATCAAATGATGGGCGAGGAATCGCGAATTCAACCTGTGGAAGTATTTTGTTTAGAATTTGCA
Protein Sequence 
>gi|13449076|ref|NP_085292.1| invasion protein [Shigella flexneri 5a str. M90T] MQILNKILPQVEFAIPRPSFDSLSRNKLVKKILSVFNLKQRFPQKNFGCPVNINKIRDSVIDKIKDSNSGNQLFCWMSQERTTYVSSMINRSIDEMAIHNGVVLTSDNKKNIFAAIEKKFPDIKLDEKSAQTSISHTALNEIASSGLRAKILKRYSSDMDLFNTQMKDLTNLVSSSVYDKIFNESTKVLQIEISAEVLKAVYRQSNTN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: transposon mutants of ipgB cannot invade epithelial cells and cannot induce keratoconjunctivitis in mice (Ménard et al., 1993).
References
Ménard et al., 1993: Ménard R, Sansonetti PJ, Parsot C. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. Journal of bacteriology. 1993; 175(18); 5899-5906. [PubMed: 8376337].