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traT from Escherichia coli O127:H6 str. E2348/69

Victor ID 3598
Gene Name traT from Escherichia coli O127:H6 str. E2348/69
Sequence Strain (Species/Organism) Escherichia coli O127:H6 str. E2348/69
NCBI Gene ID 7056350
NCBI Protein GI 215276226
Locus Tag E2348_P1_046
Protein Accession YP_002332189.1
Other Database IDs UniProtKB-ID: B7UTJ2_ECO27
UniRef100: UniRef100_Q0H0A2
UniRef90: UniRef90_P15177
UniRef50: UniRef50_P15177
UniParc: UPI0000DD4F23
EMBL: FM180569
EMBL-CDS: CAS07482.1
RefSeq_NT: NC_011603.1
EnsemblGenome: EBESCG00000113294.
EnsemblGenome_TRS: EBESCT00000114169
EnsemblGenome_PRO: EBESCP00000107199
GenomeReviews: FM180569_GR
KEGG: ecg:E2348_P1_046
HOGENOM: HBG320895
OMA: GITAYNS
ProtClustDB: PRK13731
Taxonomy ID 574521
Plasmid No pMAR2
Gene Starting Position 45291
Gene Ending Position 46022
Gene Strand (Orientation) -
Protein Name conjugal transfer surface exclusion protein TraT
DNA Sequence 
>gi|215276192:45291-46022 Escherichia coli O127:H6 str. E2348/69 plasmid pMAR2, complete sequence
ATCAGAGAATATTTGCGATTGATTTGGCCAGCTGGTCTTCGAGAACAGGCTTCGCCTCTTCAAATTTCAG
GTTAACCTTGTTCGCACTGGAGACCACACGGGTCTGATATTTATGCTGGTTACCTGTTTCAGTACTGGTC
TGAATTTTCGCACCTGAAGTGCCCTGACGCAGGGCGGCAACATTATCTGTTGTCACCGTTGTCTTAGTAC
GCTCTGCAATCTGCACATCCGTGATCATGGTATAGTTCACATCTTCCACCATCGCATCTGCAGCCATACC
CACCAGACCAGCAGCAAGGCCCACACCGAGTGTGGCACCGGCAGAATTGGAATTATATCCGGTAATACCG
GCACCTAACGCTGCACCAACAGCTGCGCCTTCATAACCACGGTTCAGCCATCCCTGAGACTCCCGCAGAT
CCATCTTATCGGCCTTCAGCACATTCGCCTGAATCCAGTAGTAGGCTTTATCCGGAGAAGTCACCACCTG
ATACCCTTTTGCTTTCACAGCATCAGCAATTTTGCCCTGCAGCCCACTCATGTCTTTATCAGAGGTGTTT
TTGATCTGCAGAAATACCGTGCGTTCGCTGGCGGGTTCAAGCCAGATGGTCTCACTCATCTGGGTCTTCA
CCTCAAGGTTACGCTTCTTGATTGCTGTGCTCATCGCACCACACCCTGAAAGGGCCAGAGTGGAACTGAC
CAGTGCAACCATCATCAATTTTTTTGTTTTCA
Protein Sequence 
>gi|215276226|ref|YP_002332189.1| conjugal transfer surface exclusion protein TraT [Escherichia coli O127:H6 str. E2348/69] MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIWLEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVNYTMITDVQIAERTKTTVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSSANKVNLKFEEAKPVLEDQLAKSIANIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: traT mutants have altered membrane permeability and are sensitive to hydrophobic antibiotics (Sukupolvi and O'Connor, 1987).
References
Sukupolvi and O'Connor, 1987: Sukupolvi S, O'Connor D. Amino acid alterations in a hydrophobic region of the TraT protein of R6-5 increase the outer membrane permeability of enteric bacteria. Molecular & general genetics : MGG. 1987; 210(1); 178-180. [PubMed: 3323837].