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bfpE from Escherichia coli O127:H6 str. E2348/69

Victor ID 3593
Gene Name bfpE from Escherichia coli O127:H6 str. E2348/69
Sequence Strain (Species/Organism) Escherichia coli O127:H6 str. E2348/69
NCBI Gene ID 7056322
NCBI Protein GI 215276200
Locus Tag E2348_P1_009
Protein Accession YP_002332163.1
Other Database IDs UniProtKB-ID: B7UTD7_ECO27
UniRef100: UniRef100_Q47071
UniRef90: UniRef90_Q47071
UniRef50: UniRef50_Q47071
UniParc: UPI00000B0425
EMBL: FM180569
EMBL-CDS: CAS07445.1
RefSeq_NT: NC_011603.1
EnsemblGenome: EBESCG00000111465.
EnsemblGenome_TRS: EBESCT00000115116
EnsemblGenome_PRO: EBESCP00000108538
GenomeReviews: FM180569_GR
KEGG: ecg:E2348_P1_009
HOGENOM: HBG368588
OMA: WHPFAEL
ProtClustDB: CLSK2298659
Taxonomy ID 574521
Plasmid No pMAR2
Gene Starting Position 8637
Gene Ending Position 9695
Gene Strand (Orientation) +
Protein Name transmembrane protein
DNA Sequence 
>gi|215276192:8637-9695 Escherichia coli O127:H6 str. E2348/69 plasmid pMAR2, complete sequence
TATGAAAGAGAAATTAAACAGACTGCTATTCACGTCGAAAACGAGAATGCGTGTTTTTAGCAAATTATCC
AGGTATCTAAGTAATGGTGTTCCAGTAACGTTTGCCCTAGCTGAGCTTTATAAGTTTACGTCTGATGAGG
GAAGAAAAAAAGATAATCCGGATGCATTTGCCCTGCAAAGATGGTTAATTGCTGTAAGAAACGGGAAAAC
ATTGGCTGAAGCGATGAGGGGGTGGGTACCTTTTGACGAACTGTCAATAATTTCCGCCGGGGAAATCTCA
GGTAATGTTCACCAGGCGTTGGATGATATCATTTATATGAATGATACAAAAAAGAAAGTAAAAGGCGCAC
TGGCAGGGATTATTTATCCTGTAGTCCTGCTTCTGACGACATGTCTGTATTTGCATATATTTGGAACTCA
GGTTGTTCCGGCATTTTCAGGCATCCTGCCTGTAGAGAAATGGCAGGGCGCAGGCAGGACTATGTATTAT
CTTGCTGTATTCGTTCAGGATTATCTTGTCATTACACTGCTGTCTTTTATGATGGTGATATTATTAATAC
TGGCAACTCTGTCAAGATGGACCGGAAGGTTGCGTCTCTTCTTTGACAGATTTATTCCCTGGTCGATATA
CAAAACCATTATAGGATGTGGTTTCTTGTTATCACTGGCATCGCTTATTAATGCAGGTATCCCTGTACCG
GAAGCCTTACGAATAATAATGAAAACGGCAAGTCCGTGGTATAAGGAAAGATTAGTTGCTATAAGATACA
GATTATTAAATGGAGAGAGAAATCTTGGGGAGGCCCTTAATTCATCTGGTTACATTTTCCCATCCAAACA
GATGATAATGGATCTCCGTTCTTATGCTGCACTTGGAGGCTTTGATGAAATGCTTAATAAACTTTCAGTT
CAATGGCAGGATGACAGTGTTGCTTATATAACGAAACAAATGACTGTTCTGAAAAATGTTGCTATCATTA
TTATGGGGCTTGTATTTATGTGGATAGTATCAGGAATGTTTTCATTACAACAACAAATTAGTGATGCAGC
AAGATTCTG
Protein Sequence 
>gi|215276200|ref|YP_002332163.1| transmembrane protein [Escherichia coli O127:H6 str. E2348/69] MKEKLNRLLFTSKTRMRVFSKLSRYLSNGVPVTFALAELYKFTSDEGRKKDNPDAFALQRWLIAVRNGKTLAEAMRGWVPFDELSIISAGEISGNVHQALDDIIYMNDTKKKVKGALAGIIYPVVLLLTTCLYLHIFGTQVVPAFSGILPVEKWQGAGRTMYYLAVFVQDYLVITLLSFMMVILLILATLSRWTGRLRLFFDRFIPWSIYKTIIGCGFLLSLASLINAGIPVPEALRIIMKTASPWYKERLVAIRYRLLNGERNLGEALNSSGYIFPSKQMIMDLRSYAALGGFDEMLNKLSVQWQDDSVAYITKQMTVLKNVAIIIMGLVFMWIVSGMFSLQQQISDAARF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bfpE mutant strain of EPEC fails to form detectable BFP and fails to carry out autoaggregation and localized adherence to HEp-2 epithelial cells in tissue culture (Blank and Donnenberg, 2001).
COG COG1459NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Blank and Donnenberg, 2001: Blank TE, Donnenberg MS. Novel topology of BfpE, a cytoplasmic membrane protein required for type IV fimbrial biogenesis in enteropathogenic Escherichia coli. Journal of bacteriology. 2001; 183(15); 4435-4450. [PubMed: 11443077].