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dppA from Escherichia coli IAI1

Victor ID 3586
Gene Name dppA from Escherichia coli IAI1
Sequence Strain (Species/Organism) Escherichia coli IAI1
NCBI Gene ID 7125629
NCBI Protein GI 218556099
Locus Tag ECIAI1_3703
Protein Accession YP_002389012.1
Other Database IDs UniProtKB-ID: B7M3G2_ECO8A
UniRef100: UniRef100_P23847
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI0000129845
EMBL: CU928160
EMBL-CDS: CAR00501.1
RefSeq_NT: NC_011741.1
EnsemblGenome: EBESCG00000131153.
EnsemblGenome_TRS: EBESCT00000135622
EnsemblGenome_PRO: EBESCP00000126713
GenomeReviews: CU928160_GR
ProtClustDB: CLSK880713
BioCyc: ECOL585034:ECIAI1_3703-MONOMER
Taxonomy ID 585034
Gene Starting Position 3771427
Gene Ending Position 3773034
Gene Strand (Orientation) -
Protein Name dipeptide transporter ; periplasmic-binding component of ABC superfamily
DNA Sequence 
>gi|218552585:3771427-3773034 Escherichia coli IAI1, complete genome
ATTATTCGATAGAGACGTTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACCACCTGT
GCTTGTTTGTACAGTTCAACACGCTTGTTGTGGTCGTCGGTGGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGGTGCTCGCCATCTTTCGCA
CGCTTGAGATACTCACCCCATTCGTAGGTGACGATTTTGGCCTGCACGCCCACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATCGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAGGTGTAGTCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACACCCGCGCCCTGAT
AAACCGCTTTGATGATCGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCGAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGATTGATGGAT
TTATCCTGCTTCATGCGAGCGATGTCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCATTCTTCTGCA
ATTTCGCGTAACGCACGGAAGCATCAGGGGTAATAGAGAAAACCAGCGTATCGATCTGCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTGTAGCGGATACGGGAGTCTTTTTGGTACTGCTGTAACTGGAACGGACCG
GTTCCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCGTCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGTCGAGTCAGCACAAACTG
AACGGTGTTATCGTCCACCTTTTTCACTTCGCTGATCAGCTCTGGCAAGCCCATACCTTCAAAGTATTCG
TAGCTGCCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACGT
CATCGGCGTTCAGTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCGGTGGTG
CCGATTTTAAATTCAACCAGGCGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTAGTACCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|218556099|ref|YP_002389012.1| dipeptide ABC transporter periplasmic-binding protein [Escherichia coli IAI1] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].