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ompA from Escherichia coli IAI1

Victor ID 3585
Gene Name ompA from Escherichia coli IAI1
Sequence Strain (Species/Organism) Escherichia coli IAI1
NCBI Gene ID 7124740
NCBI Protein GI 218553544
Locus Tag ECIAI1_0998
Protein Accession YP_002386457.1
Other Database IDs UniProtKB-ID: B7M886_ECO8A
UniRef100: UniRef100_A8VTC9
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0001886114
EMBL: CU928160
EMBL-CDS: CAQ97862.1
RefSeq_NT: NC_011741.1
EnsemblGenome: EBESCG00000131714.
EnsemblGenome_TRS: EBESCT00000131994
EnsemblGenome_PRO: EBESCP00000127165
GenomeReviews: CU928160_GR
HOGENOM: HBG741096
ProtClustDB: PRK10808
BioCyc: ECOL585034:ECIAI1_0998-MONOMER
Taxonomy ID 585034
Gene Starting Position 1071441
Gene Ending Position 1072565
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|218552585:1071441-1072565 Escherichia coli IAI1, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATGCCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCAGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACCGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCAGACCGTTGTCCGGACGAGTACCGATGGTGTTTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCACCTGCGAAAACCGGAGAAACGCCAG
TGTCGTGGTCTTTAAAGGATGCGCCACCAGGTACGTTAGCCTTGGTGTCTGCACGCCATACCATACCACC
CAGACGAGTGTATACGTCCAGATCGTCAGTGATTGGGTAACCCAGTTTAGCAGTCAGTTGAACGCCCTGA
GCTTTGTATGCACCGTTGATGTTGTCGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAA
AACCAACATACGGGTTAACCTGGTAACCACCAAAAGCACCTGCACCCAGTTGGTTTTCGTGGGTCGGACC
ATTGTTAGGAATAAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTA
TCTTTCGGAGCGGCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTT
TCATTTTTTGCGCCTCGTTATCATCCAAAATACGCCATGAATATCTCCAACGAGATAACACGGTTAAATC
CTTCA
Protein Sequence 
>gi|218553544|ref|YP_002386457.1| outer membrane protein A [Escherichia coli IAI1] MKDLTVLSRWRYSWRILDDNEAQKMKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].