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tia from Escherichia coli S88

Victor ID 3583
Gene Name tia from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7133342
NCBI Protein GI 218559962
Locus Tag ECS88_3256
Protein Accession YP_002392875.1
Other Database IDs UniProtKB-ID: B7MN20_ECO45
UniRef100: UniRef100_Q4FBH2
UniRef90: UniRef90_Q4FBH2
UniRef50: UniRef50_Q46678
UniParc: UPI0000553297
EMBL: CU928161
EMBL-CDS: CAR04490.1
RefSeq_NT: NC_011742.1
EnsemblGenome: EBESCG00000140118.
EnsemblGenome_TRS: EBESCT00000136236
EnsemblGenome_PRO: EBESCP00000129167
GenomeReviews: CU928161_GR
OMA: DNYSASK
ProtClustDB: CLSK2467286
BioCyc: ECOL585035:ECS88_3256-MONOMER
Taxonomy ID 585035
Gene Starting Position 3229671
Gene Ending Position 3230426
Gene Strand (Orientation) -
Protein Name Tia invasion determinant
DNA Sequence 
>gi|218556939:3229671-3230426 Escherichia coli S88, complete genome
GTCAGAAGTTATAAGTCACACCAAACATGATGTCGTGACTTTTAACGTCAGCCTCTGATTTATATTTATC
CCCTTCTGCATCCTTGTAAGACAGGGAGGATTTACCAGCATCCAGATAGCGATAGCTGAGGTCAAGAGCG
ATATCCGGGGTTATGTCATAGCGAACACCGGCCCCAATGCTCCATGCGAAATTGTTATCATATCCCGAGT
AATGCAACGCAGAAATATCGCTCACCTCACCAGATTTATTCCAGGAGGTATCAGTATATGTTGCCTTATG
ATGTATCCGTGCATAACCCAGTCCAACAGACACCCATGGAGTGAATGCACTGCTGTTTCTGAAGTCATAA
TACGTATTCACCATCAGGGTATTCACACTGAGCCTGTTCTGTGTGTCTTCCCGACCACCATCCCCCATCG
GAGAATGCCATGTATCCAGTGTATAATGGGAGTCTGCAGCTCCGCGGCCATAGAATTCCACTTCCGTGCG
CACAGGAACATTGTAATGTTGATAAAAATCATAGCCCACCGCAAGGCCTGCACCAAATACAGTATCGTTT
TTATCACCGCCCTTATACTTATAAACATCATCCCCAAAGTCCTGACGGAAGCGCTGGTCAGTCTGAGTCA
CAACCGAAGCACCAGCTTTACCGGTCACATAAAAGCCTGTTTTACCCCTATCAGCCAGAGCCTGGGCTGA
AAATACGCCCGCCATAGCAAGCGCTGAAACAACAATAACCTTTTTCATTTCAATCA
Protein Sequence 
>gi|218559962|ref|YP_002392875.1| Tia invasion determinant [Escherichia coli S88] MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDIMFGVTYNF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tia deletion strains were noninvasive and lacked the ability to adhere to human ileocecal cells (Fleckenstein et al., 1996).
COG COG3637M, under M: Cell wall/membrane/envelope biogenesis
References
Fleckenstein et al., 1996: Fleckenstein JM, Kopecko DJ, Warren RL, Elsinghorst EA. Molecular characterization of the tia invasion locus from enterotoxigenic Escherichia coli. Infection and immunity. 1996; 64(6); 2256-2265. [PubMed: 8675335].