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ecpA from Escherichia coli S88

Victor ID 3576
Gene Name ecpA from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7130299
NCBI Protein GI 218557210
Locus Tag ECS88_0290
Protein Accession YP_002390123.1
Other Database IDs UniProtKB-ID: B7MCA4_ECO45
UniRef100: UniRef100_B7MCA4
UniRef90: UniRef90_P0C8Z9
UniRef50: UniRef50_P0C8Z9
UniParc: UPI000188644D
EMBL: CU928161
EMBL-CDS: CAR01644.1
RefSeq_NT: NC_011742.1
EnsemblGenome: EBESCG00000135649.
EnsemblGenome_TRS: EBESCT00000137871
EnsemblGenome_PRO: EBESCP00000129726
GenomeReviews: CU928161_GR
HOGENOM: HBG298879
OMA: ATWKATA
ProtClustDB: CLSK879619
BioCyc: ECOL585035:ECS88_0290-MONOMER
Taxonomy ID 585035
Gene Starting Position 310043
Gene Ending Position 310630
Gene Strand (Orientation) -
Protein Name E. coli common pilus (ECP)
DNA Sequence 
>gi|218556939:310043-310630 Escherichia coli S88, complete genome
ATTAACTGGTCCAGGTAGCGTCGAACTGTACGCTAACGTCGCCGCTCCAGATGCCTTCCGGTAGAGTGCT
GTAATCGGTTACTGCGGTGGTAGCATTGGTGGTGCCGCTGATGATGGAGAAAGTGAAACCATCCTGTGCG
GTGGTACGATTGCTGGCATTGTAACCGTTAGCCAGTGGGCTAAGGTTGCCGCCCAGTACGCCGTTGGCGG
TATCGATCATCACGGTATCGCCAGTTTTTTCGACTGCCGCGCCGTTATAATCCACGCCCACATTCAGTGT
GGAACCTGAGGTATCCAACTGGGTTAAGGTGTTGGTGATAAGGCGTGAGGTCAGTTTAAAGGCGGTAGCC
GTTGAGTCACCCTCGATAGCCACGTCAAATAGACCTTTTTGTGAGTTAAAACCTTTAATGCCTTCGGCAT
ACTGGAACGCCAGGCTACCGAGTGGCGTCACAACCAGCTTACTGGTGGTGTCTTTTTTGGCTGTTGCTGA
CCAGGTCGCTACAGCCTGAGCTGTTACGTCAGCAGCCTGCGCTACACCTGTACCGGTAAACACCGTTACC
AGAGCTATTGCCAGAACCTTTTTTTTCA
Protein Sequence 
>gi|218557210|ref|YP_002390123.1| common pilus ECP [Escherichia coli S88] MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSIISGTTNATTAVTDYSTLPEGIWSGDVSVQFDATWTS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ecpA mutant had attenuated adherence to HEp-2 cells compared to the parental EHEC strain (Rendón et al., 2007).
References
Rendón et al., 2007: Rendón MA, Saldaña Z, Erdem AL, Monteiro-Neto V, Vázquez A, Kaper JB, Puente JL, Girón JA. Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(25); 10637-10642. [PubMed: 17563352].