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ompA from Escherichia coli S88

Victor ID 3574
Gene Name ompA from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7130155
NCBI Protein GI 218557855
Locus Tag ECS88_0978
Protein Accession YP_002390768.1
Other Database IDs UniProtKB-ID: B7MIB0_ECO45
UniRef100: UniRef100_Q9L6J0
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI00000BC823
EMBL: CU928161
EMBL-CDS: CAR02310.1
RefSeq_NT: NC_011742.1
EnsemblGenome: EBESCG00000138947.
EnsemblGenome_TRS: EBESCT00000136326
EnsemblGenome_PRO: EBESCP00000130918
GenomeReviews: CU928161_GR
OMA: DDNEAQK
ProtClustDB: PRK10808
BioCyc: ECOL585035:ECS88_0978-MONOMER
Taxonomy ID 585035
Gene Starting Position 1018890
Gene Ending Position 1019930
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|218556939:1018890-1019930 Escherichia coli S88, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATGCCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAATCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATTTTGTCTGCCGGGATACCTTTAGAGATCAGGTAATCAACAACGGACTGAG
CACGACGCTCGGACAGAGCCTGGTTATAAGCGTCAGAACCGATGCGGTCAGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGGTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCATACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
TACGTCCAGATCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGCTGAACGCCCTGAGCTTTATATGCA
CCGTTTTCAACGCTGCCTTTGTATGGCATACGACCTAACCAGTCATAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGACCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|218557855|ref|YP_002390768.1| outer membrane protein A [Escherichia coli S88] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQALSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].