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aslA from Escherichia coli S88

Victor ID 3573
Gene Name aslA from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7129944
NCBI Protein GI 218560864
Locus Tag ECS88_4222
Protein Accession YP_002393777.1
Other Database IDs UniProtKB-ID: B7MH62_ECO45
UniRef100: UniRef100_E2QHX4
UniRef90: UniRef90_P25549
UniRef50: UniRef50_P25549
UniParc: UPI00000DF2CE
EMBL: CU928161
EMBL-CDS: CAR05416.1
RefSeq_NT: NC_011742.1
EnsemblGenome: EBESCG00000136320.
EnsemblGenome_TRS: EBESCT00000136714
EnsemblGenome_PRO: EBESCP00000129030
GenomeReviews: CU928161_GR
HOGENOM: HBG374065
OMA: PTRATIM
ProtClustDB: CLSK880785
BioCyc: ECOL585035:ECS88_4222-MONOMER
Taxonomy ID 585035
Gene Starting Position 4191849
Gene Ending Position 4193504
Gene Strand (Orientation) -
Protein Name arylsulfatase-like enzyme
DNA Sequence 
>gi|218556939:4191849-4193504 Escherichia coli S88, complete genome
CTTAGTCAGATTTAATCTGCGCGCGTGGTGGATATTTTTTCAGGATCTCCATATACGCGTGCATTTCGGT
CTGTAGCGGTACACCCATCGGAATATGGCGCACGCCGATAGAGTCGCTTTCCTGCGGATCGGTGTACAGG
TTAAACACCGACGATCCCGCCGTTTGCATTACTGTGCCGGTGAATCCACCCTGATATCCGCTCTGGGTAT
AAGCGTAAGGTTGCTGAATCAGGACGTGATACTTGAACTCATCCATACGCACAGCAGAAAGTTTACCGTT
GAGGAAGTAGTGCTCGGCCTTACGGTTAGACTGACCATTTGTTCCCAGGAAGAAAGATGTCTGGTCCACA
CCATCGATAAAGGTGGTTTTCGGTACTAAATTCGCTACTTTCGCCCCAGGATGCCCCGCCAGATCCAGCG
CCGTAGGGAAGAGATCCGCCAGATCGACAATGCCGTCAGATTTACGCGGTTGGATCATGCCTTTCCAGTA
AACGAAGGTTGGCACACGAACGCCGCCTTCCCATGTAGAACCTTTCGCACCGCGGAACGGCGTGCGACCG
TGCGGCGGAACTTCGGCTTCCGGACCGTTATCAGAGGTGAACACAATCAGCGTGTTATCAAGCTGACCGT
TTTTCTCCAGTGCTTTATACAGATTGGCGAAGATATCGTTCATCTCCACCATGCAGTCGCCGTAAGAGGT
GCGCGCCGGAGAGCTACCCGCATATTTGGCGTTCGGGTAGTTATCGAAGTGACAGCCGCGAGTGCCGTAA
TAGAGGAAGAAAGGCTTATCACTCTTCGCCATCTTGTCGAGGAACTTAACGCCATATTCCATCCAGCGTT
GATCCAGGTCTTCCATATATTTCGGCGTAATGTCGGCAATGGCTTCCTGTTCACCGCCGCGCACGGCATG
AACGTCATCTTTGCTGAACGGCAGTTTTTGGATGTATTCAGAACGAGCCGGGCTCAGGGCGACTTCCGGG
TTGACATGAACATCACGCCATTCGGTATACATATCGGACACCGAGTTAAAGCCGCGGAAATCATCAAAGC
CAACGTTCTGCGGCTGCGACTCTTTGTTTTCCCCCATATGCCATTTCCCGATAGCCTGGGTGACGTAGCC
CTGATCGTGCAGCAACTGCGGCAGCGTGGTTAACCCTTGCAGACCGCCCGGTTGCCCGTACATTGGCGGC
ATCAGAATGCCGTGGTGGATGGAGTATTGTCCGGTGAGAATCGTGGCGCGGGTTGGGGAAGAACTCGGTT
GAGAATACGCCGAAGTTAAAATCAGCCCCTGGCTGGCAACGGCGTCGATATCTGGTGTAGGGTTACCCAC
CGCCACGCCGCCGCCGTTAAAGCCAACGTCCATCCAGCCCACATCATCCAGCAAGAAAACAACCACGTTC
GGTTTCTTACCGGTTTTTTTCTCAAGTTCCGCCAGTTTCTGCTGGGTTTCTTTGTCTTGTGCAGGATGCT
GCATCACCGGCATCATGTTGTCGGCAATAGTGGTCGCCGGTTTAACCAGATACTGGTTTGGGTGATCGTA
TCCGGCAAAGCCTTTGCGTGCGGTGGCGGTTGACGGGGTATCTGCTGCGCTGGCTATGAGAGGAAGAGCT
GCGGCGACAGCAACAACAAGAAGTTTGGGTGAAAACGAAAATTCCA
Protein Sequence 
>gi|218560864|ref|YP_002393777.1| arylsulfatase-like enzyme [Escherichia coli S88] MEFSFSPKLLVVAVAAALPLIASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPARSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWMEYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFANLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: disruption mutant was less invasive in an in vitro HBMEC invasion assay than the wild-type E. coli K1 (Hoffman et al., 2000).
COG COG3119P, under P: Inorganic ion transport and metabolism
References
Hoffman et al., 2000: Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS. Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infection and immunity. 2000; 68(9); 5062-5067. [PubMed: 10948126].