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hemC

Victor ID 357
Gene Name hemC
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899174
NCBI Protein GI 15644865
Locus Tag HP0237
Protein Accession NP_207035.1
Other Database IDs UniProtKB-ID: HEM3_HELPY
UniRef100: UniRef100_P56140
UniRef90: UniRef90_Q17W61
UniRef50: UniRef50_A7GYU4
UniParc: UPI000012C479
EMBL: AE000511
EMBL-CDS: AAD07304.1
RefSeq_NT: NC_000915.1
GenomeReviews: AE000511_GR
KEGG: hpy:HP0237
NMPDR: fig|85962.1.peg.233
TIGR: HP_0237
HOGENOM: HBG624842
OMA: SLHAVGQ
ProtClustDB: PRK00072
Taxonomy ID 85962
Gene Starting Position 246628
Gene Ending Position 247548
Gene Strand (Orientation) -
Protein Name porphobilinogen deaminase
DNA Sequence 
>gi|15644634:246628-247548 Helicobacter pylori 26695, complete genome
ATTAAAACAACTGCGCCTTTTCTAAAATCTCTTTAGCCCCGCTTTGCAAAAATTCTTCTAAAAGCTCTTG
AACTAAATCAAACGCTTTAGTTTTATCCCCTTGTTTTTCTTTAGTAATGACTTCTTTCCCGTTAGGCAAG
CCTAAAACCGCCTGGATTTTAACCCTATCGCCCATTAAACTCGCATGCACGCCTATAGGGATCTGACACC
CTCCATTAAGCCCCTTGATAAACTCCCTTTCTAAACGGCAGCAAAACGCGCTTTTCTCGTCGTTGAGTTT
TTGAAGCGTGGCAAAATGCTTGTGGTTTTTGAGCATTTCTACCCCTAAAGCCCCCTGACCCATGCTAGGA
ATCATTTCTTCTACGCTAAAAGCCTTGCGGTATTTCGCTCCTTGAATTTCTAGGCGGCACAACCCGGCTT
CAGCTAAAATGATAGCGTCAAATTCTCCGCATTCAAGCTTTTTCAAACGGGTTTGGACATTCCCTCTCAA
GCTTTCTGTGTCCAAATCCTGGCGCTTTAATTTGATCTGCATAGAGCGCCTTAAAGAAGTCGTGCCAACC
TTTGCCCCTTTAGGCAAACTCATCAAATCAGGGAATTTCACGCTTAAAAAAGTGTCCCTCACATCAGCCC
TTTTGGTGATGCATGCCAAGTCTAACCCCTTTTCAAACACGACCGGCACGTCTTTTAAAGAATGCACCGC
CAAATCAATTGCGCCCTTTAAAAGCAATTCTTCTAATTCCTTAGTGAATAGCCCCTTACCGCCGATCTTA
TTTAAAGGGGTGTCTAAGATTTTATCGCCCTTAGTCTTAACGATTTGAATTTCGCTTTCTATCAAGCATT
CTTTTTTCAGGCGTTCTTTAATGTGATTCGCTTGCCATAAGGCTAATTCGCTCCCCCTAGAGCCAATCAC
TAAATTTCCCA
Protein Sequence 
>gi|15644865|ref|NP_207035.1| porphobilinogen deaminase [Helicobacter pylori 26695] MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAKYRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQIPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEILEKAQLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a hemC mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG0181H, under H: Coenzyme transport and metabolism
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].