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iucA from Escherichia coli S88

Victor ID 3566
Gene Name iucA from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7119436
NCBI Protein GI 218534490
Locus Tag pECS88_0013
Protein Accession YP_002401020.1
Other Database IDs UniProtKB-ID: B7LI18_ECO45
UniRef100: UniRef100_B7JCC1
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI0001885462
EMBL: CU928146
EMBL-CDS: CAQ87086.1
RefSeq_NT: NC_011747.1
EnsemblGenome: EBESCG00000138345.
EnsemblGenome_TRS: EBESCT00000140401
EnsemblGenome_PRO: EBESCP00000130415
GenomeReviews: CU928146_GR
OMA: SFLNCYL
ProtClustDB: CLSK908239
Taxonomy ID 585035
Plasmid No pECOS88
Gene Starting Position 11531
Gene Ending Position 13318
Gene Strand (Orientation) -
Protein Name Aerobactin siderophore biosynthesis protein IucA
DNA Sequence 
>gi|218534477:11531-13318 Escherichia coli S88 plasmid pECOS88, complete sequence
TTCAGACCTCCTGAGCCTGCAGCGGGTTAGCGAAATCAAAATAGATCACCGAAGGGTCAACGATGGTGTT
CTCGTTATGATCGTTCAGATAACAGAAAAAGTTACCTTTTACGTTCCAGTACGGACTTTCCAGAACATAG
TTGAGACAGGTTTTATGAGTCACCTGGTCACGCACTTCAGCCAGCAATGTTCGTACACGAGCCATCAGAT
TCGCTTCGCTGTCCAGCCCGGCAGCACCCAGCGCAGCAGTTACGGCAAAAGTGGAGTTAACCAGCAGGTA
ATAAGGGAAATAGCGCAGCAACTGCTCACGGGTGAAAATATTTTCCGCCTGCGCCTCGTCAATGGTATCG
AGCCACTCTGTCGCGTGAGGCATAAACGCGCTGCCCTGGCAGTCACGGTAAATAAATCCGACCGGCAGAT
CCCCAAGCATCTGCACAAGAATATTTTGCTGATGCGCCAGCAGCACCAGGCCGTAATCCGCTTCAGCCGT
AAACAGAGGCTTCAGCACCTGCTGACAGTAAGCATCGACCCATGCGTGGGCGGCCTGTTGCACAGTGATA
CCGAGGCGATCGCTCAGGCGTTTTACCGCCGAAACCAGCAGCGAATCACCGCCATCCGGTGCGGCCTGAG
TCAGGGAAACCAGAACGTTGGTCTGGCTTTGCGGCTGCTCCAGCAGCAGGTTTTCACGCAGGGAAAACAA
ACTTTCCTGCATGATGTTGCCGTTAAGATCGCGCAGCCCGGCCCAGCCGTCCTCCTGCATTACCCGGAAA
GTAGGGAAGCGGGCCTGTAGCATCTGCCAGCCGTCGGTTTGCGCCAGACGTGCCAGGCGCATTCCTCGCT
CCACCTCTTTCACAGACAGAGTACGGACGGAGTTGGTCAGCCGAACGCTCAGGGAGAACTTGATCATATC
GCGGCTGGTAGCACAGTAGAGGGAGCGGGAAGAGGTGGTCGGCAGCCACGACGTGCCGGCCTCGCCTAAG
TCTCTGATAAGTCCTTTAGCAAAAAGTGCCTGGCACCACACTTGCTGCAAAAGATATTCTCCCTGCCACG
GGTGCAGCGGGAACAGCCATTGATTGTCACTTAATTCGTTGAGTAACTGGGGCGCATTTTCTGCGGCAAA
TCGCGTCAACCGCTGTTGAAGGTTAAGATGCAGACTTTCACCAGCGATTTGCGTTTTATCCACCGAAAAC
CACCGCAGCGGGAAGTGAGGTGCCATGTCAGGCAGGTATCGTTCAGCTTCCTGGCGGTTAAACGGTTCAT
GAGACTTAGGTGCAGGGTGGAAAGCGTGTCCTGTCAGCAGTGCCTGCTCAGCCTCGCCAAAATTCAACGC
TTTTTCACGCAGGATGGCCCAGTCATGGCGGGCATCAATTGTCTGTTGCGTATGGGCGTAGCTTTCCAGC
ACGCGTTGGTGGAAAGTTTCGCAGAGGGGAACTGGCAGAAAAAGTTGATGCCGGAGCTTATCAATAATAA
GCCGGGAGAGAGTGGTAAAGTCGACAGGATAACTGCCTGATGCCGTGACCAGATGAGCAGGAAATGCAAA
GCGGTGATGCTGGGTTGGGGAGAAATAAGCCACTCTGAAATGGAGCGACTTCTGTTCGTCCAGCGGGATA
ATCAATTCGTCTGGCGGGTATTCCGCCAGTTGCCAGTCTTTGGTTTCACGAATCAAGGCATTCAGGAAGC
ACTGCGCAGCCACATCTGTGGCGGATTTTTCAGAGGGCAGGATCATAATCAAACAGCTCCTACACAGTAA
AATAATAACAATTATGTCAATAATGATTCTCATTATCA
Protein Sequence 
>gi|218534490|ref|YP_002401020.1| Aerobactin siderophore biosynthesis protein IucA [Escherichia coli S88] MIMRIIIDIIVIILLCRSCLIMILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDLNGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (de and Martinez, 1988).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
de and Martinez, 1988: de Lorenzo V, Martinez JL. Aerobactin production as a virulence factor: a reevaluation. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988; 7(5); 621-629. [PubMed: 2973985].