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iroN from Escherichia coli S88

Victor ID 3562
Gene Name iroN from Escherichia coli S88
Sequence Strain (Species/Organism) Escherichia coli S88
NCBI Gene ID 7119392
NCBI Protein GI 218534588
Locus Tag pECS88_0124
Protein Accession YP_002401118.1
Other Database IDs UniProtKB-ID: B7LIB9_ECO45
UniRef100: UniRef100_B7LIB9
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00018851D0
EMBL: CU928146
EMBL-CDS: CAQ87187.1
RefSeq_NT: NC_011747.1
EnsemblGenome: EBESCG00000140092.
EnsemblGenome_TRS: EBESCT00000138802
EnsemblGenome_PRO: EBESCP00000130066
GenomeReviews: CU928146_GR
OMA: TMVVEST
ProtClustDB: PRK13528
Taxonomy ID 585035
Plasmid No pECOS88
Gene Starting Position 99850
Gene Ending Position 102012
Gene Strand (Orientation) +
Protein Name outer membrane receptor FepA
DNA Sequence 
>gi|218534477:99850-102012 Escherichia coli S88 plasmid pECOS88, complete sequence
TATGAGAATTAACAAAATCCTCTGGTCGCTAACTGTGCTCCTGGTTGGGTTGAATAGCCAGATATCAGTA
GCCAAATCCTCCGACGATGATAATGACGAGACTCTGGTGGTGGAAGCCACCGCTGAGCAGGTATTAAAAC
AGCAGCCGGGCGTGTCGGTTATTACCAGCGAGGATATTAAAAAGACCCCTCCGGTAAACGACCTTTCAGA
TATTATTCGTAAAATGCCTGGTGTCAATCTTACCGGCAATAGCGCCTCGGGCACACGCGGTAATAACCGC
CAGATCGATATTCGAGGTATGGGGCCGGAAAACACCTTAATTTTAATTGATGGTGTACCGGTGACGTCAC
GTAACTCCGTGCGTTATAGCTGGCGTGGAGAGCGTGATACCCGCGGTGACACCAACTGGGTGCCACCGGA
ACAGGTTGAGCGTATTGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGGGCAGCCGGGGGG
GTGGTGAACATCATTACCAAACGTCCCACCAACGACTGGCACGGTTCGCTGTCGTTATACACCAATCAGC
CGGAAAGTAGCGATGAGGGCGCTACGCGTCGCGCCAATTTCAGCCTTAGTGGGCCTCTGGCTGGTAATGC
TCTTACCACGCGTTTGTATGGTAACCTGAATAAAACGGATGCTGACAGTTGGGATATTAATTCTCCGGTC
GGTACGAAAAACGCAGCCGGGCATGAAGGGGTACGTAACAAAGATATTAACGGCGTTGTCTCGTGGAAAT
TAAATCCGCAGCAGATTCTCGATTTCGAAGCCGGATATAGCCGCCAGGGGAATATCTATGCGGGCGATAC
GCAAAACAGTTCTTCCAGTGCAGTTACCGAAAGCCTGGCAAAATCCGGCAAAGAGACGAACCGCCTGTAC
CGACAGAATTATGGCATTACGCATAATGGTATCTGGGACTGGGGACAAAGTCGCTTTGGTGTTTATTACG
AGAAAACCAATAATACCCGCATGAATGAAGGATTATCCGGCGGTGGTGAAGGGCGTATTTTAGCGGGTGA
AAAGTTTACGACCAATCGCCTGAGTTCCTGGCGAACCAGCGGCGAGCTTAATATTCCTTTGAATGTGATG
GTTGATCAAACGCTGACCGTTGGTGCAGAGTGGAACCGCGATAAGCTCGATGATCCTTCCTCTACCAGCC
TGACGGTGAATGACAGTGATATCAGCGGTATTTCTGGCTCTGCTGCGGATCGCAGCAGTAAAAATCATTC
TCAAATCAGTGCGCTGTATATTGAAGATAACATTGAGCCGGTTCCTGGCACGAATATCATTCCCGGCCTG
CGCTTTGATTATCTCAGCGACTCCGGCGGGAACTTCAGCCCCAGTCTGAATCTTTCGCAGGAATTGGGCG
ATTATTTCAAAGTCAAAGCAGGGGTTGCCCGAACCTTTAAAGCCCCAAACCTGTATCAATCCAGTGAAGG
CTATCTGCTCTACTCGAAAGGCAATGGCTGTCCAGGCGGGTGCTACCTGATCGGTAATAAAGATCTCGAT
CCGGAAATCAGCGTCAATAAAGAAATTGGGCTGGAGTTCACCTGGGAAGATTACCACGCAAGTGTGACCT
ACTTCCGCAATGATTACCAGAATAAGATCGTGGCCGGGGATAACGTTATCGGGCAAACCGCTTCAGGCGC
ATATATCCTCAAGTGGCAGAATGGCGGGAAAGCTCTGGTGGACGGTATCGAAGCCAGTATGTCTTTCCCA
CTGGTGAAAGATCGTCTGAACTGGAATACCAATGCCACATGGATGATCACTTCGGAGCAAAAAGACACCG
GTAATCCTCTGTCGGTCATCCCGAAATATACTATCAATAACTCGCTTAACTGGACCATCACCCAGGCGTT
TTCTGCCAGCGTCAACTGGACGTTATATGGCAGACAAAAACCGCGTACTCATGCGGAAACCCGCAGTGAA
GATACTGGCGGTCTGTCAGGTAAAGAGCTGGGCGCTTATTCACTGGTGGGGACGAACTTCAATTACGATA
TTAATAAAAATCTGCGTCTTAATGTCGGCGTCAGTAATATCCTCAATAAACAGATCTTCCGATCTTCTGA
AGGGGCGAATACCTATAACGAGCCAGGCCGGGCTTACTATGCCGGAGTTACCGCATCATTCTG
Protein Sequence 
>gi|218534588|ref|YP_002401118.1| outer membrane receptor FepA [Escherichia coli S88] MRINKILWSLTVLLVGLNSQISVAKSSDDDNDETLVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGNALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDSDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASVNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroA gene cluster mutants were unable to resist Lcn2 in mouse serum (Fischbach et al., 2006).
COG COG4771P, under P: Inorganic ion transport and metabolism
References
Fischbach et al., 2006: Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(44); 16502-16507. [PubMed: 17060628].