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ureC

Victor ID 356
Gene Name ureC
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899104
NCBI Protein GI 15644702
Locus Tag HP0072
Protein Accession NP_206872.1
Other Database IDs UniProtKB-ID: URE1_HELPY
UniRef100: UniRef100_P69997
UniRef90: UniRef90_B6JPH5
UniRef50: UniRef50_Q03284
UniParc: UPI000002C20A
EMBL: M60398
EMBL: X17079
EMBL: AE000511
EMBL: M84338
EMBL-CDS: AAA25021.1
EMBL-CDS: CAA34933.1
EMBL-CDS: AAD07143.1
EMBL-CDS: -
RefSeq_NT: NC_000915.1
PDB: 1E9Y
PDB: 1E9Z
MINT: MINT-1567059
MEROPS: M38.982
GenomeReviews: AE000511_GR
KEGG: hpy:HP0072
TIGR: HP_0072
HOGENOM: HBG357507
OMA: MPYTINT
ProtClustDB: PRK13985
Taxonomy ID 85962
Gene Starting Position 75526
Gene Ending Position 77235
Gene Strand (Orientation) -
Protein Name urease subunit alpha
DNA Sequence 
>gi|15644634:75526-77235 Helicobacter pylori 26695, complete genome
CCTAGAAAATGCTAAAGAGTTGCGCCAAGCTCACTTTATTGGCTGGTTTAGAAGTTACTTCTTTGCCATC
CACGAACACATGGTAAGTTTCAGGATTGACTTCAATGTGAGCGGTAGTGTCGTTGAATTGCATGTCTTTT
TTAGTGATGTTTCTGCAATTTTTTACCGGCAACACTTGTCTTTCAAGCCCTAATTCTTCTTTAATGCCTT
TGTCATAAGCCGCTTGAGACACAAAAGTGATGTTTGCATCGTATTTGGCTTTACCATGATGAGCGAACAT
TTCTCTGTAATAAACTGGTTGTGGGGTAGGGATAGAAGCGTTCGCGTCACCCATTTGACTCAACGCAATG
AACCCGCCTTTGATGATCATGTTGGGTTTTACGCCAAAGAATGCGGGACTCCACAATACCAAGTCAGCCA
CTTTGCCCACTTCTACAGAACCTACATACTCGCTAATCCCATGAGCGATCGCTGGGTTAATGGTGTATTT
AGACAAGTAGCGTTTGATCCTGAAGTTGTCGTTATCGCCTTTTTCTTCTTTCAAGCGGCCAAATTCTTTT
TTGTTTTTGTCAGCTGTTTGCCAAGTTCTAGTGATAACTTCACCCACACGACCCATAGCTTGAGAGTCAG
AGCTGGTGATTGAGAAAATCCCCATGTCATGCAAAGTGTCTTCAGCCGCAATGGTTTGAGGGCGGATCCT
TGAATCAGCGAACTGAACATCTTCTTTAATGCTTTTATCCAAGTGGTGGCACACCATAAGCATGTCCATG
TGTTCTGCTTCTGTATTCACAGTGAAAGGGATAGTGGGGTTAGTGGAAGCGGGAAGAATGTTGTGTTCAC
CAGCTACTTTAATAATATCAGGAGCGTGTCCGCCGCCAGCACCTTCAGTGTGGAAAGTGTGCATAGTGCG
TCCGGCAATAGCTGCCATAGTGTCTTCCACGCAACCGGCTTCATTCAAAGTGTCTGTGTGGATAGCGACT
TGCACATCGTATTTGTCTGCAACATCTAACGCATGATTGATTGCAGAAGGAGTGGTGCCCCAGTCTTCGT
GGATTTTAAAGCCAATCGCACCAGCTTCAATTTGATCGGCTAAGCTCGCGTCGTTAGAAGCGTTACCTTT
AGCCAAGAAACCTAAGTTCATAGAATATTCTTCAGCCGCTCTGAGCATCCATTTTAAATTTCTTCTGCCT
GGAGTGATAGTAGTCGCATTAGTGCCATCAGCAGGACCAGTTCCGCCACCAATCATGGTTGTTACACCGC
TTGCAAAAGCTGTAGGGATTTGTTGGGGTGAAATGAAGTGGATGTGTGTGTCAATACCACCAGCAGTTAC
GATCAAACCTTCACCGGCTAAGGCTTCAGTAGCAGGACCTACGCTAAGATTGTTTTTAACGCCATCTTGC
ATGTCTTTGTTACCGCCTTTACCAATGCCAGCGATTTTGCCATCTTTAATACCAATATCCGCTTTATAAA
TACCGGTGTAATCCACGATTAAAGCGTTAGTGATGATTAGATCCAATTCTTCTTTGCTAGGGTTGTTGGA
TTGGCTCATGCCTTCTCTCAGGGTTTTACCGCCACCGAATTTAAGCTCTTCGCCATAAATGGTGTAGTCA
TGTTCTACTTCAGCGATCAAGTCTGTATCGCCCAATCTCACTTTATCGCCTGTAGTAGGGCCATACATAG
AAACATATTCTTTTCTGCTAATCTTTTTCA
Protein Sequence 
>gi|15644702|ref|NP_206872.1| urease subunit beta [Helicobacter pylori 26695] MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKVSLAQLFSIF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a ureC mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG0804E, under E: Amino acid transport and metabolism
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].