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dppA from Escherichia coli ED1a

Victor ID 3549
Gene Name dppA from Escherichia coli ED1a
Sequence Strain (Species/Organism) Escherichia coli ED1a
NCBI Gene ID 7140515
NCBI Protein GI 218691829
Locus Tag ECED1_4223
Protein Accession YP_002400041.1
Other Database IDs UniProtKB-ID: B7N1J2_ECO81
UniRef100: UniRef100_E2QGQ2
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI00000E4A94
EMBL: CU928162
EMBL-CDS: CAR10212.1
RefSeq_NT: NC_011745.1
EnsemblGenome: EBESCG00000141514.
EnsemblGenome_TRS: EBESCT00000142451
EnsemblGenome_PRO: EBESCP00000134466
GenomeReviews: CU928162_GR
OMA: TVELWAM
ProtClustDB: CLSK880713
BioCyc: ECOL585397:ECED1_4223-MONOMER
Taxonomy ID 585397
Gene Starting Position 4142422
Gene Ending Position 4144029
Gene Strand (Orientation) -
Protein Name dipeptide transporter ; periplasmic-binding component of ABC superfamily
DNA Sequence 
>gi|218687878:4142422-4144029 Escherichia coli ED1a, complete genome
ATTATTCGATAGAGACATTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACGACCTGT
GCTTGTTTGTACAGTTCAACACGTTTATTGTGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGATGCTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACGATTTTGGCCTGCACGCCCACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCATTCGGGTTATACGGACGTTGTACCGGCATTGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAAGTGTAGTCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACGCCCGCGCCCTGAT
AAACCGCTTTGATGATGGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCCAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGGTTGATGGAT
TTATCCTGCTTCATGCGGGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCGTTCTTCTGCA
ATTTCGCGTAACGCACGGAAGCGTCAGGAGTAATAGAGAAGACCAGCGTATCGATCTTCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTATAGCGAATACGGGAATCTTTCTGGTACTGCTGTAACTGGAACGGGCCG
GTACCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCGTCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG
AACGGTGTTATCGTCCACCTTTTTCACTTCGCTGATCAGCTCTGGTAAGCCCATGCCTTCGAAGTATTCG
TAGCTGCCGCCAGAGACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACTACGT
CATCGGCATTCAGTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCAGTGGTG
CCGATTTTAAATTCAACCAGACGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTGCCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|218691829|ref|YP_002400041.1| dipeptide ABC transporter periplasmic-binding [Escherichia coli ED1a] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].